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Best Price*  ₹ 100.00
MRP ₹125.00
(Inclusive of all taxes) *4 Tablet(s) in a Strip * Mfr: Alkem Laboratories Ltd (Generics) * Country of Origin: India



INTRODUCTION

ZENEGRA 50MG contains Sildenafil which belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. It is used to treat adult men with erectile dysfunction, also known as impotence. It happens when a man cannot get, or keep a hard, erect penis suitable for sexual activity. Erectile dysfunction (ED) is inability of men to attain and maintain an erect penis with sufficient rigidity to allow sexual intercourse. This medicine works by helping to relax the blood vessels in penis, allowing blood to flow into penis when you get sexually excited. 

Sildenafil acts by inhibiting PDE-5 and enhancing NO action in the penis. The mechanism of erection of the penis involves release of nitric oxide (NO) during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), resulting in smooth muscle relaxation and inflow of blood to the penis.

Always take this ZENEGRA 50MG exactly as directed by your doctor. It is not suitable for women or children and adolescents under 18 years of age. Before taking this medicine tell your doctor if you have severe heart or liver problems, if you have recently had a stroke or heart attack or if you have low blood pressure. Tell your doctor know if you suffer from these or any other health problems before taking it.

USES OF ZENEGRA 50MG

  • Treats erectile dysfunction (ED)

HOW ZENEGRA 50MG WORKS

Sildenafil works by helping to relax the blood vessels which allows increased blood flow into the penis when you get sexually excited.

DIRECTIONS FOR USE

Always take this medicine exactly as your doctor has directed you. Swallow medicine whole with a glass of water. Do not take more than once a day.

SIDE EFFECTS OF ZENEGRA 50MG

SERIOUS

  • erection (priapism)
  • sudden vision loss (one or both eyes)
  • sudden hearing decrease or hearing loss

COMMON

  • headache
  • flushing
  • upset stomach
  • abnormal vision andblurred vision
  • stuffy or runny nose
  • back pain
  • muscle pain
  • nausea
  • dizziness
  • rash

RARE

  • fainting or irregular heartbeat
  • decreased blood flow to parts of the brain, feeling of tightening of the throat, numb
  • eye problems
  • seeing halos around lights
  • penile bleeding, presence of blood in semen
  • dry and swelling of the inside of the nose

HOW TO MANAGE SIDE EFFECTS

Feeling sick (nausea) or indigestion:

Stick to simple meals and do not eat rich or spicy foods.

Headache:

Rest and drink plenty of fluids.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

WARNING & PRECAUTIONS

DRIVING AND USING MACHINES

ZENEGRA 50MG may cause dizziness or affect your vision. Do not drive or handle any machines while taking this medicine.

ALCOHOL

Drinking alcohol can impair your ability to get an erection. Do not drink excessive amounts of alcohol while taking this medicine.

KIDNEY

ZENEGRA 50MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.

LIVER

ZENEGRA 50MG is not recommended in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take if you are allergic (hypersensitive) to Sildenafil or any other ingredients in this medicine.

HEART DISEASE

ZENEGRA 50MG is not recommended in patients with severe heart disease. Consult your doctor for advice.

OTHERS

Tell your doctor if you have or had a condition such as,

  • low blood pressure
  • sickle cell anaemia, leukaemia, multiple myeloma (cancer of bone marrow)
  • inherited eye diseases (retinitis pigmentosa)
  • loss of vision
  • deformity of your penis or Peyronie’s disease
  • stomach ulcer or bleeding problem (haemophilia)

INTERACTIONS

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

  • nitroglycerin
  • amyl nitrite
  • riociguat (used to treat pulmonary arterial hypertension)
  • protease inhibitors (used to treat HIV)
  • alpha-blockers (terazosin hydrochloride)
  • other medicines for erectile dysfunction

SYNOPSIS

Drug :   Sildenafil
Pharmacological Category :   Phosphodiesterase-5 Enzyme Inhibitor
Therapeutic Indication :   Erectile dysfunction
Dosage Forms :   Tablet, Capsule, Oral solution, Injection, Jelly, Spray

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ZENEGRA 50MG

Can I take ZENEGRA 50MG for premature ejaculation?

No, it is not known to have any beneficial effects in treating premature ejaculation. It is used for treatingerectile dysfunction.

Does ZENEGRA 50MGaffect fertility?

No, it does not affect fertility, neither negatively nor positively.

Is ZENEGRA 50MG safe to use in patients with diabetes?

Yes, if prescribed by your doctor then this medicine is safe to use in patients with diabetes.

REFERENCES

1. KD Tripathi MD. Hormones and related drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 304.

2. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page 752-53.

3. Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page - 197.

4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page 1261-62.

5. James G McMurray, Robert A Feldman, Stephen M Auerbach, Herb DeRiesthal, Neal Wilson. Long-term safety and effectiveness of sildenafil citrate in men with erectile dysfunction: Therapeutics and clinical risk management. Dec 2007. [Accessed Oct 3, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387281/

6. Upjohn UK Limited,Fareva Amboise, Zone Industrielle. Electronic Medicines Compendium (EMC); [Revised June 2020] [Accessed Dec 31,2020] https://www.medicines.org.uk/emc/files/pil.3172.pdf

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Manufacturer/Marketer Details

    Net Qty
    1
    Shelf Life
    NA
    Item Weight
    NA
    No. of Units in a Kit
    NA
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