INTRODUCTION

ZACLO CN CREAM is a combination of Clobetasol, Clotrimazole and Neomycin which belongs to the group of medicines called Corticosteroids, Antifungals and Antibiotics respectively. It is used to treat bacterial, fungal skin infections with associated inflammation.

This medicine should be used as directed by the physician. It is for external use only. Avoid contact eyes. It should not be used for any disorder other than that for which it was prescribed. The treated skin area should not be bandaged, otherwise covered, or wrapped so as to be occlusive unless directed by the physician.

ZACLO CN CREAM can be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Contact your doctor before applying. ZACLO CN CREAM should be used with caution in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.

Safety and effectiveness of ZACLO CN CREAM in pediatric patients have not been established. Contact your doctor before applying. The most common side effects of this medicine are skin rash, urticaria, itching, redness, swelling, burning, stinging sensation and skin irritation. Contact your physician if any of the symptoms worsen.

USES OF ZACLO CN CREAM

• Used to treat bacterial, fungal skin infections with associated inflammation

HOW ZACLO CN CREAM WORKS

ZACLO CN CREAM helps to treat infection, where Clobetasol belongs to Corticosteroids which blocks the production of certain chemical messengers that make the skin red, swollen, and itchy. Clotrimazole belongs to antifungal agent which stops the growth of fungi while Neomycin is an antibiotic which stops the growth of bacteria in the skin.

DIRECTIONS FOR USE

Apply ZACLO CN CREAM as directed by your physician. It is for external use only. Apply a thin layer of the medicine to the affected area of the skin and rub it gently. Your doctor will prescribe the right dose depends on your age, body weight and severity of infection.

SIDE EFFECTS OF ZACLO CN CREAM

HOW TO MANAGE SIDE EFFECTS

Skin Rash Or Itching

Avoid hot showers because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if itching worsens.

WARNING & PRECAUTIONS

PREGNANCY

Consult your doctor

ZACLO CN CREAM can be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Contact your doctor before applying.

BREASTFEEDING

Use with Caution

ZACLO CN CREAM should be used with caution in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.

ALLERGY

Contraindicated

Do not use ZACLO CN CREAM if you are allergic to Clobetasol, Clotrimazole, Neomycin, or any other ingredients of this medicine.

USE IN PEDIATRICS

Consult your doctor

Safety and effectiveness of ZACLO CN CREAM in pediatric patients have not been established. Contact your doctor before applying.

INTERACTIONS

A. Drug-Drug interactions:

Before taking ZACLO CN CREAM tell your doctor if you are taking any of the following medicines:

• aminoglycosides like amikacin, gentamicin, neomycin (medicines used for bacterial infections)

Overdosage:

If you or anyone else accidentally uses too much of ZACLO CN CREAM, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Store ZACLO CN CREAM below 25°C

FAQs ABOUT ZACLO CN CREAM

Q: What are the possible side effects of using ZACLO CN CREAM?

A: The most common side effects of this medicine are skin rash, urticaria, itching, redness, swelling, burning, and stinging sensation, skin irritation. Contact your physician if any of the symptoms worsen.

Q: Can I use ZACLO CN CREAM in children?

A: Consult your doctor before using ZACLO CN CREAM in children because safety and effectiveness have not been established.

Q: Does ZACLO CN CREAM cause itching on the skin?

A: Yes, ZACLO CN CREAM may cause skin itching at the site of application as a temporary side effect. However, if the itching persists or worsens, consult your doctor for advice.

Q: How to use ZACLO CN CREAM?

A: Apply ZACLO CN CREAM as directed by your physician. It is for external use only. Wash your hands with soap and water and apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with eyes. Do not cover or wrap, bandage the skin unless directed by the doctor.

Q: Can I stop using ZACLO CN CREAM when my symptoms are relieved?

A: No, do not stop using ZACLO CN CREAM and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.

REFERENCES

1. K.D. Tripathi. Corticosteroids & Aminoglycoside Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895,750.

2. Bethesda (MD). Clobetasol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/5311051

3. Bethesda (MD). Clotrimazole. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/2812

4. Bethesda (MD). Neomycin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Neomycin

5. Torrent Pharmaceuticals ltd. Clobetasol + Clotrimazole + Neomycin. [Accessed on 24th June 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2478.pdf