INTRODUCTION

WYMESONE 0.5MG contains Dexamethasone which belongs to a group of medicines called Corticosteroids which occur naturally in the body. It is used to reduce the inflammation and suppress the immune system in conditions such as allergies, polymyalgia rheumatic, polyarteritis nodosa, blood disorders, leukaemia, myeloma, crohn’s disease, ulcerative colitis, hepatitis, polymyositis, increased pressure in the head not linked to tumours, worsening of multiple sclerosis, inflammation of the eye and kidney, breathing problems, rheumatoid arthritis, chronic and severe diseases of the skin, leukaemia of the lymphatic system, Hodgkin’s and Non-Hodgkin’s lymphoma, Kahler’s disease (cancer of blood cells) and high calcium levels caused by this disease.

Dexamethasone is a synthetic glucocorticoid (adrenocortical hormone), which boosts your body and treats various illnesses involving inflammation in the body. Before taking WYMESONE 0.5MG inform your doctor if you have liver, kidney or heart problems, are pregnant or breastfeeding. Your physician will give the correct dose depends on your child’s age and body weight. The common side effects are increased appetite, irritability, difficulty sleeping, swelling in your ankles, feet and heartburn.

USES OF WYMESONE 0.5MG

Used to reduce the inflammation and suppress the immune system in conditions such as

• allergies
• polymyalgia rheumatic, polyarteritis nodosa
• blood disorders
• leukaemia, myeloma
• crohn’s disease, ulcerative colitis, hepatitis
• polymyositis
• increased pressure in head and worsening of multiple sclerosis
• inflammation of the eye and kidney
• breathing problems
• rheumatoid arthritis
• chronic and severe diseases of the skin
• Hodgkin’s and Non-Hodgkin’s lymphoma, Kahler’s disease
• also used in the treatment of coronavirus disease 2019 (COVID-19)

HOW WYMESONE 0.5MG WORKS

Dexamethasone works by decreasing inflammation (swelling), prevents infection and fights with white blood cells and also alters the body's normal immune system responses.

DIRECTIONS FOR USE

Always take WYMESONE 0.5MG as instructed by your doctor. Swallow whole and do not crush or chew.

SIDE EFFECTS OF WYMESONE 0.5MG

HOW TO MANAGE SIDE EFFECTS

Difficult sleeping:

Wake up at the same time each day, exercise regularly and do not eat and make your sleeping environment comfortable.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking,

• ritonavir, cobicistat, indinavir or saquinavir (used for HIV)
• warfarin (treats blood clots)
• captopril or verapamil (treats high blood pressure)
• colestyramine
• amphotericin B, rifabutin, rifampicin, ketoconazole (treats infections)
• erythromycin, praziquantel and isoniazid
• aspirin, indometacin, hydrocortisone, cortisone (treats pain)
• insulin, metformin and chlorpropamide (treats diabetes)
• antacids, charcoal and carbenoloxone (treats stomach problems)
• aminoglutethimide, methotrexate and thalidomide (used for cancer)
• ephedrine (helps to tighten blood vessels)
• phenytoin, carbamazepine, primidone, phenobarbital and acetazolamide (treats epilepsy)
• oestrogen and progestogen including the contraceptive pill
• tetracosactide (used in the test for adrenocortical function)
• barbiturates or sulpiride (used to calm emotions)
• ciclosporin (used to stop the rejection of organs after transplants)
• MMR, tuberculosis, yellow fever or oral typhoid (live vaccines)
• neostigmine (for myasthenia gravis)
• medicines used to lower potassium levels

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT WYMESONE 0.5MG

Can I stop taking WYMESONE 0.5MG when my symptoms are relieved?

No, do not stop taking and complete the full course of treatment even if you feel better.  

Can the use of WYMESONE 0.5MG cause sleeping problem?

Yes. It may cause sleeping problem in some individuals, consult your doctor for advice.

Is WYMESONE 0.5MG effective?

Yes, it is effective if used in the prescribed dose and frequency as instructed by your physician.

REFERENCES

1. KD Tripathi MD. Corticosteroids. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 289.

2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 377-379.

3. Mukhtar H. Ahmed and Arez Hassan. Dexamethasone for the Treatment of Coronavirus Disease (COVID-19): a Review. Oct, 2020. [Accessed on June 21, 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599121/

4. Glenmark Pharmaceuticals Europe Limited. RAFARM S.A. [Revised on Nov, 2020] [Accessed on June 21, 2021] https://www.medicines.org.uk/emc/files/pil.816.pdf