VYLDA M 500mg Tablet 10's

Introduction About VYLDA M 500MG TABLET

What is VYLDA M 500mg Tablet?

VYLDA M 500mg Tablet combines Vildagliptin (50mg) and Metformin (500mg) to effectively manage type 2 diabetes mellitus when diet and exercise alone are insufficient.

Vildagliptin (DPP-4 inhibitor) increases insulin production after meals and reduces glucagon levels, while Metformin decreases liver glucose production and improves insulin sensitivity for comprehensive blood sugar control.

Adults with type 2 diabetes not controlled by metformin alone. Patients needing combination therapy for better glycemic control. Overweight diabetics seeking weight-neutral treatment. Take VYLDA M 500mg Tablet with meals (morning and/or evening) as prescribed. Swallow whole with water. Do not crush or chew the tablet.

Before taking VYLDA M 500mg Tablet, inform your doctor if you have liver, kidney, or heart problems. It should be used during pregnancy only if advised by your doctor, and it is not recommended for pregnant women. VYLDA M 500mg Tablet is not suitable for use in children and adolescents under 18 years of age, and it should be used with caution in elderly patients (65 years of age and above).

The common side effects are nausea, stomach upset, headache (usually temporary). Serious side effects are lactic acidosis risk (seek immediate help for severe fatigue, muscle pain). Monitor kidney function regularly during treatment.

Uses Of VYLDA M 500MG TABLET

• Used to manage type 2 diabetes mellitus when diet and exercise alone are insufficient

Benefits of VYLDA M 500MG TABLET

• Controls high blood sugar levels in type 2 diabetes patients
• Reduces risk of diabetes complications (heart disease, kidney damage, neuropathy)
• Weight neutral - suitable for overweight diabetic patients
• Low risk of hypoglycemia compared to sulfonylureas
• Convenient once/twice daily dosing with meals

How VYLDA M 500MG TABLET Works

Vildagliptin (DPP-4 inhibitor) increases insulin production after meals and reduces glucagon levels, while Metformin decreases liver glucose production and improves insulin sensitivity for comprehensive blood sugar control.

How to use VYLDA M 500MG TABLET

Take VYLDA M 500mg Tablet with meals (morning and/or evening) as prescribed. Swallow whole with water. Do not crush or chew the tablet.

Recommended dosage and timing

Take VYLDA M 500mg Tablet once or twice daily as prescribed by your doctor, typically in the morning and/or evening. The exact dose depends on your blood sugar levels, response to treatment, and medical condition. Consistency at the same time each day maximizes effectiveness.

Taking VYLDA M with meals

Take VYLDA M 500mg Tablet with or immediately after meals to minimize gastrointestinal side effects like nausea or stomach upset associated with metformin. Swallow the tablet whole with water, do not crush, chew, or break it.

What if I forgot to take VYLDA M 500MG TABLET

Take the missed dose as soon as you remember. If it is nearly time for your next dose, skip the missed one and resume your regular schedule. Never double the dose to compensate, as this increases side effect risks

Overdose

If you or anyone else accidentally takes too much of VYLDA M 500MG TABLET, consult your doctor immediately. Overdosage symptoms of VYLDA M 500MG TABLET might include low blood sugar levels, lactic acidosis, muscle pain, mild and transient burning or tickling sensations in the body, fever, and oedema.

Side Effects Of VYLDA M 500MG TABLET

Common Side Effects of VYLDA M 500MG TABLET:

• Nausea
• stomach upset
• headache (usually temporary)

When to consult a doctor?

• lactic acidosis risk (severe fatigue, muscle pain)

Warning & Precautions

Other Warnings for VYLDA M 500MG TABLET

Before taking VYLDA M 500MG TABLET, inform your doctor if you have or had:

• pancreatic disease
• Vitamin B12 deficiency
• Malnutrition with adrenal or pituitary insufficiency

Who should not take VYLDA M 500MG TABLET

VYLDA M 500MG TABLET is not recommended for you if you have:

• Type 1 diabetes mellitus
• Uncontrolled diabetes
• Severe infection or seriously dehydrated
• are going to have a contrast x-ray (a specific type of x-ray involving an injectable dye)

Diet and Lifestyle Advice

• Balanced carbohydrate diet: Choose complex carbs (whole grains, vegetables, legumes) over refined sugars and processed foods. Portion control at meals helps maintain steady glucose levels.
• Regular meal timing: Eat at consistent times daily, pairing medication doses with breakfast and/or dinner to optimize absorption and reduce stomach upset.
• Physical activity: Aim for 30 minutes of moderate exercise (walking, yoga, cycling) most days to improve insulin sensitivity and support weight management.
• Hydration: Drink 2-3 liters of water daily to support kidney function and prevent dehydration, especially important with metformin.
• Fiber-rich foods: Include high-fiber fruits, vegetables, and whole grains to slow glucose absorption and reduce gastrointestinal side effects.
• Limit alcohol: Avoid or minimize alcohol consumption to prevent hypoglycemia and lactic acidosis risk.
• Weight monitoring: Track weight regularly; the medication is weight-neutral but lifestyle changes amplify benefits for overweight patients.
• Blood sugar tracking: Use a glucometer regularly and maintain a food/exercise diary to identify patterns and adjust habits.

Drug - Drug interaction

Drug/Class	Interaction Description	Potential Effect	Precaution / Advice
Insulin / Sulfonylureas	Additive blood sugar lowering effect	Hypoglycemia (low blood sugar)	Monitor glucose levels; dose adjustment needed
Diuretics (e.g., furosemide)	May increase dehydration risk and affect kidney function	Electrolyte imbalance, kidney stress	Monitor hydration and kidney function
Beta-blockers	May mask hypoglycemia symptoms	Delayed recognition of low blood sugar	Regular glucose monitoring required
NSAIDs / Painkillers (aspirin, ibuprofen)	Increased risk of kidney impairment	Reduced kidney function	Use cautiously; monitor renal function
Contrast dyes (for imaging)	Risk of lactic acidosis if kidney function impaired	Severe metabolic complication	Stop VYLDA M before procedures; resume after
Anticoagulants (warfarin)	Possible effect on blood clotting control	Altered INR levels	Monitor coagulation parameters
Alcohol	Increases lactic acidosis risk and hypoglycemia	Severe adverse reactions	Avoid excessive alcohol consumption

Synopsis

Drug	:	Metformin, Vildagliptin
Pharmacological Category	:	Biguanides, Dipeptidyl peptidase 4 inhibitors
Therapeutic Indication	:	Type II diabetes mellitus
Dosage Forms	:	Tablet

More Information

• Store in a cool, dry place below 30°C
• Keep out of reach of children

FAQs About VYLDA M 500MG TABLET

Q: What is VYLDA M 500MG TABLET used for?

A: VYLDA M 500MG TABLET is used to manage type 2 diabetes mellitus in adults by improving blood sugar control.

Q: Can VYLDA M cause weight gain?

A: No, it is weight neutral unlike some diabetes medications.

Q: What if I miss a dose?

A: Take as soon as remembered unless near next dose.

Q: Is VYLDA M safe for kidney patients?

A: Dose adjustment needed; consult doctor.

Q: What are the side effects of VYLDA M 500MG TABLET Tablet?

A: The most common side effects of taking VYLDA M 500MG TABLET Tablet are nausea, vomiting, stomach pain, headache, low blood sugar, and diarrhea. Contact your doctor if any of the symptoms worsen.

Q: Which is better, VYLDA M 500MG TABLET or metformin?

A: VYLDA M 500MG TABLET (vildagliptin) and metformin are used for different purposes in diabetes management. Metformin is often the first-line treatment due to its proven efficacy, safety, and cost-effectiveness. VYLDA M 500MG TABLET is added when metformin alone does not provide adequate blood sugar control.  It is more effective when combined with metformin (as in VYLDA M 500MG TABLET), as the dual therapy addresses blood sugar control from multiple pathways. The choice depends on individual needs, tolerability, and doctor recommendations.

Q: Is VYLDA M 500MG TABLET to be taken before or after food?

A: VYLDA M 500MG TABLET should be taken after food to minimize gastrointestinal side effects like nausea or stomach upset. Following your doctor’s instructions regarding timing and dosage is essential for optimal results.

Q: Does VYLDA M 500MG TABLET cause weight loss?

A: VYLDA M 500MG TABLET is generally weight-neutral, meaning it does not significantly cause weight gain or loss. However, metformin in the combination may contribute to mild weight loss in some individuals by improving insulin sensitivity and reducing appetite. Vildagliptin typically has no direct effect on weight.

Q: Does VYLDA M 500MG TABLET cause constipation?

A: Constipation is not a common side effect of VYLDA M 500MG TABLET. On the contrary, metformin (part of VYLDA M 500MG TABLET) is more likely to cause diarrhea or loose stools. However, individual responses vary, and if constipation occurs, it is usually mild and manageable with dietary changes and increased hydration.

Q: Does VYLDA M 500MG TABLET contain metformin?

A: The basic VYLDA M 500MG TABLET contains only vildagliptin. The VYLDA M 500MG TABLET, however, is a combination of vildagliptin (50 mg) and metformin (500 mg or 1000 mg). Ensure you are prescribed the correct formulation based on your treatment plan.

Q: How to use VYLDA M 500MG TABLET?

A: VYLDA M 500MG TABLET should be taken as directed by your doctor. Swallow the tablet whole with water, preferably after a meal to reduce stomach upset. Do not skip doses or stop the medication suddenly without consulting your doctor. Monitor your blood sugar levels regularly to ensure the medication is effective

Q: What are the benefits of VYLDA M 500MG TABLET?

A: The benefits of VYLDA M 500MG TABLET include effective blood sugar control by combining two complementary mechanisms (vildagliptin and metformin) such as Weight neutrality, suitable for overweight patients, Low risk of hypoglycemia, Compared to sulfonylureas or insulin and Convenience: Combining two medications in one tablet simplifies treatment.

Q: Does vildagliptin increase creatinine?

A: Vildagliptin does not directly increase creatinine levels, but it should be used with caution in patients with kidney impairment. Kidney function must be monitored during treatment, as vildagliptin is partially excreted by the kidneys.

Q: Which is better, vildagliptin or metformin?

A: Metformin is the preferred first-line management for type 2 diabetes due to its long-term safety, efficacy, and affordability. Vildagliptin is added for patients who need additional blood sugar control. The combination (as in VYLDA M 500MG TABLET) often provides better results than either drug alone. The choice depends on individual needs and doctor recommendations.

Q: When should I stop taking vildagliptin?

A: Vildagliptin should be stopped if Significant side effects occur, such as severe liver enzyme elevation or allergic reactions. It is ineffective in controlling blood sugar, and an alternative treatment is needed. Your doctor recommends discontinuation due to contraindications like kidney or liver dysfunction. Always consult your doctor before stopping the medication.

Q: Is VYLDA M 500MG TABLET safe?

A: VYLDA M 500MG TABLET is generally safe when used as prescribed. However, patients with kidney, liver, or heart conditions should use it cautiously under medical supervision. Regular monitoring of blood sugar levels, kidney function, and liver enzymes is essential to ensure safety.

Q: When is the best time to take VYLDA M 500MG TABLET?

A: VYLDA M 500MG TABLET is best taken after meals to reduce the risk of gastrointestinal side effects. Follow your doctor’s timing and dosing instructions for optimal results.

Q: When to take VYLDA M 500MG TABLET 50/500?

A: VYLDA M 500MG TABLET 50/500 is typically taken once or twice daily, as prescribed, after meals. Taking it with food helps improve tolerance to metformin and reduces side effects like nausea.

Q: Is Galvus and VYLDA M 500MG TABLET the same?

A: Yes, Galvus and VYLDA M 500MG TABLET are essentially the same as both contain vildagliptin. Galvus is the brand name by Novartis, while VYLDA M 500MG TABLET is marketed by another pharmaceutical company. Both are used for managing type 2 diabetes, and their effectiveness is similar. The choice between them depends on availability, cost, and doctor recommendations.

References

1. KD Tripathi MD. Hormones and related drugs. Essentials of Medical Pharmacology. Seventh edition. New Delhi, May 2013. Page-274.

2. Paresh Ved and Samrat Shah. Evaluation of vildagliptin and fixed dose combination of vildagliptin and metformin on glycemic control and insulin dose over 3 months in patients with type 2 diabetes mellitus. March 2012. [Accessed on 27th November 2025]

3. Serge Halimi, Anja Schweizer, Biljana Minic, James Foley and Sylvie Dejage. Combination treatment in the management of type 2 diabetes: focus on vildagliptin and metformin as a single tablet. March 2008. [Accessed on 27th November 2025]

4. Novartis Pharma AG. Galvus Met (Vildaglliptin + Metformin) [Revised in July 2020] [Accessed on 27th November 2025]

Useful Diagnostic Tests

• Random Blood Sugar (RBS)
• Fasting Blood Sugar (FBS)
• Post Prandial Blood Sugar (PPBS)
• Sugar Risk Package
• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin

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