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VOXVO 20 Tablet 10's

Depression
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    Introduction About VOXVO 20 TABLET

    VOXVO 20 Tablet is used to manage depression (major depressive episodes) in adults. It contains Vortioxetine, which is an Antidepressant medicine that acts by increasing the levels of certain chemical messengers (such as serotonin) in the brain that can stabilize mood and mental health.

    Depression is a mood disorder characterized by a persistent feeling of sadness, loss of interest, feeling guilty or worthless, attention impairment, lack of energy, suicidal thoughts, and slow or abnormal physical movements.

    Before taking VOXVO 20 Tablet, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you currently have or have a previous history of fits (epilepsy), glaucoma, suicidal thoughts, mania, or bleeding problems as a precaution.

    VOXVO 20 Tablet is not recommended for use in pregnant or breastfeeding women unless considered necessary by the physician. It is also not suitable for use with children under the age of 18.

    The most common side effects of taking VOXVO 20 Tablet are nausea, vomiting, diarrhea, constipation, dizziness, itching of the whole body, abnormal dreams (nightmares), and increased sweating. These side effects are usually temporary and will resolve on their own within 2 weeks of therapy. However, consult your doctor if they worsen.

    You must also inform your doctor if you experience worsening of depression or suicidal thoughts or behaviour after taking VOXVO 20 Tablet.

    Uses Of VOXVO 20 TABLET

    • To manage depression in adults

    How VOXVO 20 TABLET Works

    VOXVO 20 Tablet is an antidepressant medication. It acts by increasing the levels of certain chemical messengers (such as serotonin) in the brain that can stabilize mood and mental health. As a result, it improves your mood and energy and reduces the signs of depression.

    How to use VOXVO 20 TABLET

    Take VOXVO 20 Tablet as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It can be taken with or without food.

    Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.

    Do not stop taking VOXVO 20 Tablet without consulting your doctor, as it may make your symptoms reappear once again.

    Side Effects Of VOXVO 20 TABLET

    Common

    • Nausea, vomiting
    • Diarrhoea, constipation
    • Dizziness
    • Itching of the whole body
    • Abnormal dreams (nightmares)
    • Increased sweating

    Uncommon

    • Flushing
    • Night sweats

    Rare

    • Enlarged pupils

    Stop taking VOXVO 20 Tablet and consult your doctor immediately if you experience any of the following side effects:

    • Signs of serotonin syndrome (such as feeling agitated, hallucinations, confusion, loss of consciousness, a fast heartbeat, feeling dizzy, increased sweating, flushing, tremors, stiff muscles or muscle twitching, loss of coordination, nausea, vomiting, diarrhea, or seizures)
    • Signs of allergic reactions (such as skin rash, swelling of the hands, face, tongue, neck, or throat, increased fluid in tissues, a fast heart rate, or difficulty breathing)
    • Unexplained bleeding
    • Feeling anxious, aggressive, irritated, or angry
    • Worsening of depression, suicidal thoughts, or behaviour
    • Fits (seizures)

    How To Manage Side Effects

    Constipation

    Eat plenty of fiber-rich foods, such as fresh fruits, vegetables, and cereals, and drink plenty of water. Exercise regularly. Contact your doctor if constipation persists.

    Diarrhea

    Drink fluids, such as water or fruit juice, in enough quantity to keep yourself hydrated. Don’t take any medicine on your own to manage diarrhea without talking to your doctor. Contact your doctor if diarrhea worsens.

    Dizziness Or Drowsiness

    Try to rest and relax. Get enough sleep. Avoid driving or operating machinery if you feel dizzy. Avoid consuming alcohol, as it could aggravate your dizziness. Contact your doctor if the dizziness worsens.

    Nausea And Vomiting

    Take this medicine with or just after meals. Stick to simple meals. Avoid eating rich or spicy food. Contact your doctor if nausea worsens.

    Warning & Precautions

    Pregnancy

    Contraindicated

    VOXVO 20 Tablet is not recommended for use by pregnant women. Therefore, consult your doctor before taking VOXVO 20 Tablet.

    Breastfeeding

    Contraindicated

    VOXVO 20 Tablet may pass through breast milk, so it is generally not recommended for use in breast-feeding women. Therefore, consult your doctor before taking VOXVO 20 Tablet.

    Driving and Using Machines

    Use with Caution

    The VOXVO 20 Tablet does not impair your ability to drive or handle heavy tools. However, it may cause dizziness in some individuals. Therefore, do not drive or operate any heavy tools or machines if you experience dizziness after taking VOXVO 20 Tablet as a precaution.

    Alcohol

    Consult your doctor

    Avoid consuming alcohol while taking VOXVO 20 Tablet, as it may increase the risk of side effects.

    Kidney

    Use with Caution

    VOXVO 20 Tablet should be used with caution in patients with severe kidney diseases. Therefore, consult your doctor before taking VOXVO 20 Tablet.

    Liver

    Use with Caution

    VOXVO 20 Tablet should be used with caution in patients with severe liver diseases (such as liver cirrhosis). Therefore, consult your doctor before taking VOXVO 20 Tablet.

    Allergy

    Contraindicated

    Do not take VOXVO 20 Tablet if you are allergic to Vortioxetine.

    Use In Pediatrics

    Contraindicated

    VOXVO 20 Tablet is not recommended for use in children and adolescents (aged below 18 years) due to a lack of safety data. Therefore, consult your doctor before taking VOXVO 20 Tablet.

    Use In Geriatrics

    Use with Caution

    VOXVO 20 Tablet should be used with caution in elderly people (aged 65 years or older). Therefore, consult your doctor before taking VOXVO 20 Tablet.

    Others

    Before taking VOXVO 20 Tablet, inform your doctor if you:

    • Currently have or have a previous history of fits (or seizures)
    • Have ever had mania (a mood disorder that causes high levels of excitement)
    • Have an increased tendency to bleed or bruise easily
    • Have low sodium levels in the blood
    • Currently have or have a previous history of glaucoma
    • Are going to have a urine test
    • Have a history of bleeding problems
    • Have a previous history of suicidal thoughts

    Interactions

    A. Drug-drug interactions:

    • Opioid analgesics (Ex. tramadol, fentanyl, nefopam, morphine or morphine, codeine, dihydrocodeine, buprenorphine)
    • Selective serotonin receptor agonists (Ex. sumatriptan)
    • Antidepressants (Ex. phenelzine, iproniazid, isocarboxazid, nialamide, tranylcypromine, moclobemide, fluoxetine, paroxetine, amitriptyline, imipramine, lithium, bupropion, St. John’s wort, etc.)
    • Amino acids (Ex. tryptophan)
    • Antiparkinsonian drugs (Ex. selegiline, rasagiline)
    • Antibiotics (Ex. linezolid)
    • Antitubercular drugs (Ex. rifampicin)
    • Antiepileptic drugs (Ex. carbamazepine, phenytoin)
    • Anticoagulant drugs (Ex. warfarin, dipyridamole, phenprocoumon, aspirin)
    • Antimalarial drugs (Ex. mefloquine)
    • Antiarrhythmic drugs (Ex. quinidine)
    • Antipsychotic drugs (Ex. haloperidol, chlorpromazine, and chlorprothixene)

    Over dosage:

    If you accidentally took more VOXVO 20 Tablet than the prescribed dose, contact your doctor or go to the nearest hospital immediately. Symptoms of overdosage might include nausea, dizziness, diarrhea, stomach discomfort, flushing, feeling sleepy or drowsy, and itching of the whole body.

    Synopsis

    Drug :   Vortioxetine
    Pharmacological Category :   Selective Serotonin Reuptake Inhibitors
    Therapeutic Indication :   Depression       
    Dosage Forms :   Tablet

    More Information

    Storage

    • Keep the VOXVO 20 Tablet out of sight and reach of children
    • Store VOXVO 20 Tablet below 25°C

    FAQs About VOXVO 20 TABLET

    Q: What is the use of the VOXVO 20 Tablet?

    A: VOXVO 20 Tablet is used to manage depression (major depressive episodes) in adults. Consult your doctor before taking it.

    Q: Is VOXVO 20 Tablet a strong antidepressant?

    A: Yes. VOXVO 20 Tablet is a strong antidepressant that effectively controls signs of depression. VOXVO 20 Tablet works by increasing the levels of certain chemicals (serotonin) within the brain that stabilize mental health.

    Q: What is the best time to take the VOXVO 20 Tablet?

    A: Take VOXVO 20 Tablet approximately at the same time each day. You can take VOXVO 20 Tablet either in the morning or in the evening as per the doctor's instructions. Taking it at the same time each day will have the best effect, and it will also help you remember your daily dose.

    Q: Can VOXVO 20 Tablet be used to reduce anxiety?

    A: VOXVO 20 Tablet is a prescription medicine used to manage depression. It has been shown to reduce anxiety. However, there is no proper evidence to prove that. If you wish to control anxiety using VOXVO 20 Tablet, speak with your doctor for advice.

    Q: How does the VOXVO 20 Tablet work?

    A: VOXVO 20 Tablet works by increasing the levels of certain chemicals within the brain (such as serotonin) that control mood and mental health. As a result, it elevates your mood and makes you feel active and energetic.

    Q: Will the use of the VOXVO 20 Tablet make you feel dizzy?

    A: Yes, VOXVO 20 Tablet may make you feel dizzy. Do not drive or handle heavy machines or tools if you feel dizzy. Avoid consuming alcohol, as it can aggravate your dizziness.

    Q: Can VOXVO 20 Tablet be used in children?

    A: VOXVO 20 Tablet is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before administration.

    Q: What should I do if I forget to take a dose of VOXVO 20 Tablet?

    A: If you forget to take a dose of VOXVO 20 Tablet, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of VOXVO 20 Tablet to compensate for a missed dose, as it could lead to toxicity.

    Q: Will taking a higher dose of VOXVO 20 Tablet than the prescribed one be beneficial?

    A: No, taking a higher dose of VOXVO 20 Tablet will not be effective; rather, it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

    Q: Can I stop taking VOXVO 20 Tablet once my symptoms subside?

    A: No. Do not stop taking VOXVO 20 Tablet without consulting your doctor, even if you feel better during the middle of the therapy. You may feel better only after 2 weeks of therapy with VOXVO 20 Tablet, but it might take several weeks for you to experience complete benefits.

    Q: Can VOXVO 20 Tablet be taken daily?

    A: Yes. VOXVO 20 Tablet can be taken daily as per your doctor’s instructions. However, if you are doubtful, consult your doctor.

    Q: Can Voxvo be used by pregnant women?

    A: Voxvo is not recommended for use in pregnant women as it may harm the growing fetus. Therefore, consult your doctor before taking it.

    Q: How do I take Voxvo?

    A: Take Voxvo as advised by your physician. It can be taken with or without food. Swallow the medicine with a glass of water. Do not chew or crush the medicine.

    Q: Can I stop taking Voxvo once I start feeling better?

    A: Do not stop taking Voxvo without consulting your doctor, as it may make your symptoms reappear.

    Q: How long will it take for Voxvo to reduce my symptoms?

    A: Voxvo starts working after 1-2 weeks of therapy. However, you may notice a difference in your condition only after 2-4 weeks of therapy. It may take around 4–6 months for Voxvo to completely reduce the symptoms of depression. Therefore, take Voxvo consistently, as advised by your physician, to achieve better results.

    Q: What are the side effects of Voxvo 20mg Tablet?

    A: The most common side effects of taking Voxvo 20mg Tablet are nausea, vomiting, diarrhea, constipation, dizziness, itching of the whole body, abnormal dreams (nightmares), and increased sweating. These side effects are usually temporary and will resolve on their own within 2 weeks of therapy. However, consult your doctor if they worsen.

    Q: Can Voxvo 20mg Tablet cause constipation?

    A: Yes. Constipation is a common side effect of taking Voxvo 20mg Tablet. Eat plenty of fiber-rich foods, such as fresh fruits, vegetables, and cereals, as well as drink plenty of water and exercise more regularly when taking this medicine. Contact your doctor if this side effect bothers you.

    Q: Where can I purchase Voxvo 20mg Tablet conveniently?

    A: You can buy this medicine online through platforms like Netmeds, an online pharmacy that offers a hassle-free way to get your medications delivered to your doorstep. If you wish to buy Voxvo 20mg Tablet on Netmeds, you need a prescription from a registered medical practitioner. Netmeds has made buying online medicines more easy for consumers and is one of India's leading online pharmacies.

    Q: Is Voxvo 20mg Tablet safe?

    A: Voxvo 20mg Tablet is safe at doses prescribed by the doctor. Do not alter the dosage of this medicine without consulting your doctor.

    References

    1. KD. Tripathi. Antidepressant and Antianxiety Drugs. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 460.

    2. Mahableshwarkar AR, Jacobsen PL, Serenko M, Chen Y, Trivedi MH. A randomized, double-blind, placebo-controlled study of the efficacy and safety of 2 doses of vortioxetine in adults with major depressive disorder. NIH National Library of Medicine; National centre for biotechnology information. May 2015. [Accessed on 17th April 2024] https://pubmed.ncbi.nlm.nih.gov/26035186/

    3. Pae, C. U., Wang, S. M., Han, C., Lee, S. J., Patkar, A. A., Masand, P. S., & Serretti, A. Vortioxetine: a meta-analysis of 12 short-term, randomized, placebo-controlled clinical trials for the treatment of major depressive disorder. NIH National Library of Medicine; National centre for biotechnology information. May 2015. [Accessed on 17th April 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409435/

    4. Lundbeck Limited. Electronic Medicines Compendium (EMC). [Revised in September 2023] [Accessed on 17th April 2024] https://www.medicines.org.uk/emc/files/pil.10441.pdf

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    Author Details

    Written By Dr. N. Sai Swaroop - Pharm.D
    Reviewed For Accuracy By Dr. Aravindan Balachandran - MBBS, MD (Psychiatry)
    Last updated on 20 Apr 2024 | 10:41 PM(IST)
    Lab updated