VERMACT 12 Tablet 4's

Parasitic Worms Rx required

Best Price*  ₹ 119.20
MRP ₹149.00
(Inclusive of all taxes) *4 Tablet(s) in a Strip * Mkt: Mankind Pharma Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

VERMACT 12 contains Ivermectin which belongs to the group of medicines called anthelmintics. It is used to treat various parasitic infections such as onchocerciasis, intestinal strongyloidiasis, filarial worm infestations (e.g. lymphatic filariasis or microfilaraemia), hookworm infestations, scabies, pediculosis (head lice) and helminthiasis (such as Ascariasis (roundworms), Trichuriasis (whipworm) and Enterobiasis (Pinworm)).

Onchocerciasis (also known as river blindness) is a parasitic (worm) infection mainly affecting the skin, lymph nodes and eyes. It is characterized by skin rash, itching, bumps under the skin, enlarged glands in the neck, armpits and groin, painful eyes or blindness. Intestinal strongyloidiasis (threadworm infection) is a parasitic infection mainly affecting the skin and the intestines. It is characterized by skin rash, itching, stomach pain, vomiting and diarrhea. Lymphatic filariasis is a worm infection that affects the lymph nodes and lymph vessels, while microfilaraemia is a filarial infection affecting the blood.

Scabies is a communicable skin infection that can spread from person to person via direct skin contact, including sexual contact and contact via exposure to the clothing or furnishings used by the infected person. It is characterized by intense skin itching (mainly at night) with irritating blisters or lumps on the skin mainly affecting the regions between the fingers, underarms, breasts, penis, buttocks, scalp, palms and soles.

VERMACT 12 cannot be used prophylactically against all these infections and it does not work against adult worms. To avoid the spread of infection (e.g. scabies), frequently wash your clothing and bedding in hot water and keep all your non-washable items in a tightly sealed plastic bag for at least 3 days. Trim your nails frequently. People who come in contact with you (e.g. friends, family members and relatives) should also visit the doctor as soon as possible as a safety precaution. This medicine is generally safe and well tolerated. However, it may cause nausea, vomiting, stomach pain and muscle pain in few individuals. Contact your doctor if it bothers you. It is not recommended for use in pregnant or lactating women and in infants (weighing less than 15 kg). Consult your doctor before taking this medicine.

USES OF VERMACT 12

  • Onchocerciasis
  • Intestinal strongyloidiasis
  • Filarial worm infestations (e.g. lymphatic filariasis or microfilaraemia)
  • Hookworm infestations
  • Scabies
  • Pediculosis (head lice)
  • Helminthiasis (Ascariasis, Trichuriasis and Enterobiasis)

HOW VERMACT 12 WORKS

Ivermectin is an antiparasitic agent. It kills the parasite by selectively binding to the glutamate-gated chloride ion channels present in the nerve and muscle cells of the organisms. Binding of ivermectin to glutamate-gated chloride ion channels increase the influx of chloride ion which results in hyperpolarization, leading to paralysis and death of the parasite.

DIRECTIONS FOR USE

Take VERMACT 12 as directed by your physician. It must be taken on an empty stomach either 2 hours before or after meals. Swallow the medicine as whole with a sip of water. In case of dispersible tablet, disperse the tablet in a teaspoonful of boiled and cooled water before administration. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of the infection. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF VERMACT 12

SERIOUS

  • allergic reactions (such as skin rash, itching, sudden fever, difficulty in breathing)

COMMON

  • liver disease
  • unusual weakness, dizziness
  • nausea, vomiting, abdominal pain, diarrhea, constipation
  • sweating or fever, cough
  • headache
  • muscle or joint or body pain
  • confusion
  • redness of eyes
  • swelling of hands, feet, ankles and lymph nodes

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Stick to simple meals. Do not eat rich or spicy food.

Constipation

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Abdominal pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

Headache:  

Rest and drink plenty of fluids. Do not drink too much alcohol. Ask your doctor to recommend a painkiller.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid traveling, driving or operating any tools or machines while you are feeling dizzy. If the symptom still persists, contact your doctor for advice.

WARNING & PRECAUTIONS

PREGNANCY

VERMACT 12 is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

VERMACT 12 is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machines if your ability is affected by this medicine.

LIVER

VERMACT 12 should be used with caution in patients having liver disease. Consult your doctor before taking.

ALLERGY

Do not take this medicine if you are allergic to ivermectin.

OTHERS

Before taking VERMACT 12, inform your doctor if you:

  • have a weak immune system or if you are currently living or have lived in parts of Africa where there are cases of human parasitic infestation

INTERACTIONS

Talk to your doctor, if you are taking:

  • diethylcarbamazine citrate (DEC) (a medicine used to treat a co-infection with Onchocerca volvulus)
  • warfarin (used for blood thinning)

SYNOPSIS

Drug :   Ivermectin
Pharmacological Category :   Anthelminthics
Therapeutic Indication :   Parasitic infections
Dosage Forms :   Tablet, Dispersible tablet, Cream, Lotion, Shampoo

MORE INFORMATION

Store at room temperature and keep out of reach of children.

FAQs ABOUT VERMACT 12

Can VERMACT 12 be used in children?

Yes. It can be used in children to treat various parasitic infection, except onchocerciasis and scabies in children (aged below 5 years) and intestinal strongyloidiasis in children (below 12 years). Also, it is not recommended for use in infants weighing less than 15kg due to lack of safety data. Consult your doctor before taking.

Can [GBNKEWORD] be used during pregnancy?

It is not recommended for use in pregnant women. Consult your doctor before taking.

What are the safety measures to be taken while taking VERMACT 12?

People who come in contact with you (e.g. friends, family members and relatives) should also visit the doctor as soon as possible as a safety precaution. To avoid the spread of infection (e.g. scabies), frequently wash your clothing and bedding in hot water and keep all your non-washable items in a tightly sealed plastic bag for at least 3 days. Trim your nails frequently.

REFERENCES

1. KD. Tripathi. Anthelmintic Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 853-854.

2. James McCarthy, Alex Loukas and Peter J. Hotez. Chemotherapy of Helminth Infections. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1454-1456.

3. Gerald G. Briggs and Roger K. Freeman. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 2119-2121.

4. Zeno Bisoffi, Dora Buonfrate, Andrea Angheben, Marina Boscolo, Mariella Anselmi, Stefania Marocco, Geraldo Monteiro, Maria Gobbo, Giulia Bisoffi and Federico Gobbi. Randomized Clinical Trial on Ivermectin versus Thiabendazole for the Treatment of Strongyloidiasis. PLOS. July 2011. [Accessed 25th January 2021] https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0001254

5. A Datry, I Hilmarsdottir, R Mayorga-Sagastume, M Lyagoubi, P Gaxotte, S Biligui, J Chodakewitz, D Neu, M Danis, M Gentilini. Treatment of Strongyloides stercoralis infection with ivermectin compared with albendazole: results of an open study of 60 cases. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. May-June 1994. [Accessed 25th January 2021] https://pubmed.ncbi.nlm.nih.gov/7974685/

6. C Naquira, G Jimenez, J G Guerra, R Bernal, D R Nalin, D Neu, M Aziz. Ivermectin for human strongyloidiasis and other intestinal helminths. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. March 1989. [Accessed 25th January 2021] https://pubmed.ncbi.nlm.nih.gov/2929853/

7. Tadesse Hailu, Endalkachew Nibret, Arancha Amor, Abaineh Munshea and Melaku Anegagrie. Efficacy of Single Dose Ivermectin Against Strongyloides stercoralis Infection Among Primary School Children in Amhara National Regional State. NCBI; PMC US National Library of Medicine, National Institute of Health. June 2020. [Accessed 25th January 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297470/

8. Merck Sharp & Dohme. STROMECTOL® Ivermectin Consumer Medicine Information. [Revised on August 2020]. [Accessed 25th January 2021] https://secure.healthlinks.net.au/content/msd/cmi.cfm?product=mkcstrob

9. EUROPEENNE DE PHARMACOTECHNIE – EUROPHARTECH. Heads of Medicines Agencies (HMA). MRI Index. [Accessed 25th January 2021] https://mri.cts-mrp.eu/Human/Downloads/NL_H_3952_001_FinalPL.pdf

10. NuLife Pharmaceuticals. Iverscab Tablets (Ivermectin Tablets U.S.P. 6 Mg/ 12 Mg). [Accessed 25th January 2021] http://www.nulifepharma.com/p-products/iverscab-tablets

11. MSD BV. U.S. Food & Drug Administration. 2009. [Accessed 25th January 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050742s026lbl.pdf

PRODUCT DETAILS

    Net Qty
    1
    Item Weight
    10
    Ingredient
    IVERMECTIN 12 mg
    Hsn Code
    30049099
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VERMACT 12 Tablet 4's

VERMACT 12 Tablet 4's Mkt: Mankind Pharma Pvt Ltd

M.R.P.: Rs.149.00
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