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Ubiphene 100mg Tablet 5'S
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INTRODUCTION
UBIPHENE 100MG TABLET is a combination of Clomifene and Ubidecarenone which belongs to the group of medicines called Ovulation stimulants and Antioxidants respectively. It is used in the treatment of infertility in women (women are not ovulating properly).
The main symptom of infertility is the inability to get pregnant, a menstrual cycle that's too long (35 days or more), too short (less than 21 days), irregular or absent can mean you're not ovulating.
UBIPHENE 100MG TABLET is not recommended for use if you have or had liver disease, unusual menstrual bleeding with unknown cause, have a type of cancer that is worsened by hormones, a cyst on your ovary.
Before taking UBIPHENE 100MG TABLET inform your doctor if you are having early menopause, are infertile, stopped having periods because of underweight, had fits or seizures in the past, have fibroids in the womb, have polycystic ovaries, ovaries are swollen, have hypertriglyceridemia (an excess of fats in the blood).
UBIPHENE 100MG TABLET is not recommended for use in pregnant women and inform your doctor before taking this medicine if you are breast-feeding a baby. It is not recommended for use in children and adolescents below 18 years of age.
The most common side effects of taking UBIPHENE 100MG TABLET are nausea, vomiting, blurred vision and pelvic pain. Consult your doctor if any of the side effects worsen.
USES OF UBIPHENE 100MG TABLET
- Treats infertility in women
HOW UBIPHENE 100MG TABLET WORKS
UBIPHENE 100MG TABLET contains clomifene which acts by increasing the gonadotrophin hormones secreted by pituitary glands which in turn stimulates the maturation and endocrine activity of the ovarian follicle (stimulates the release of eggs from the ovary). Ubidecarenone protects the body from damage by chemicals that cause infertility.
DIRECTIONS FOR USE
Take UBIPHENE 100MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending upon your age, body weight and disease condition.
SIDE EFFECTS OF UBIPHENE 100MG TABLET
COMMON
- nausea, vomiting
- ovarian enlargement
- blurred vision
- abnormal uterine bleeding
- pelvic pain
RARE
Stop taking UBIPHENE 100MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- allergic reaction (signs include rash, itching, difficulty breathing, shortness of breath, swelling of your face, lips, throat or tongue, cold clammy skin, palpitations, dizziness, weakness or fainting)
- numbness, weakness or paralysis on one side of body, slurred speech, sudden blurred vision, confusion or unsteadiness (can be stroke)
- over-stimulation of the ovary (pain in the pelvis, stomach or calves, feeling bloated, passing less urine, difficulty in breathing or an increase in weight)
- blurring of vision or spots in front of the eyes
- jaundice
- sudden and severe headaches
- mental illness such as psychosis
HOW TO MANAGE SIDE EFFECTS
Nausea and vomiting:
Stick to simple meals. Avoid eating oil rich, fried or spicy food. Consult your doctor if the symptom does not improve.
WARNING & PRECAUTIONS
PREGNANCY
UBIPHENE 100MG TABLET is not recommended for use in pregnant women or women planning to have a baby. Consult your doctor before taking UBIPHENE 100MG TABLET.
BREASTFEEDING
Inform your doctor if you are breastfeeding before taking UBIPHENE 100MG TABLET as it can lower the amount of milk produced. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or use machines while taking UBIPHENE 100MG TABLET as it may cause blurred vision.
LIVER
UBIPHENE 100MG TABLET is not recommended for use in patients with liver disease or history of liver disease. Consult your doctor before taking it.
ALLERGY
Do not take UBIPHENE 100MG TABLET if you are allergic to Clomifene or Ubidecarenone or any other ingredients of this medicine.
OTHERS
UBIPHENE 100MG TABLET is not recommended for use if you:
- have unusual menstrual bleeding with unknown cause
- have a type of cancer that is worsened by hormones
- have a cyst on ovary
Before taking UBIPHENE 100MG TABLET, inform your doctor if you:
- have early menopause or have been told you are infertile
- have stopped having periods because you are under-weight
- have had fits or seizures in the past
- have fibroids in womb
- have polycystic ovaries
- ovaries are swollen
- have hypertriglyceridemia (an excess of fats in the blood) or a family history of hypertriglyceridemia
- intolerant to certain sugars
Use in pediatrics:
UBIPHENE 100MG TABLETis not recommended for use in children and adolescents below 18 years of age. Consult your child’s doctor for advice.
INTERACTIONS
A. Drug - Drug interactions:
Before taking UBIPHENE 100MG TABLET, inform your doctor if you are taking any medicines including prescription, non-prescription and herbal supplements
Overdosage:
If you or anyone else accidentally take too much of UBIPHENE 100MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are over-stimulation of the ovary (pain in the pelvis, stomach or calves, feeling bloated, passing less urine, difficulty in breathing or an increase in weight).
SYNOPSIS
| Drug | : | Clomifene citrate, Ubidecarenone |
| Pharmacological Category | : | Ovulation stimulant, Antioxidant |
| Therapeutic Indication | : | Infertility in women |
| Dosage Forms | : | Tablet, Capsule |
MORE INFORMATION
- Keep UBIPHENE 100MG TABLET out of reach of children
- Store at room temperature
FAQs ABOUT UBIPHENE 100MG TABLET
What is UBIPHENE 100MG TABLET used for?
UBIPHENE 100MG TABLET is used in the treatment of infertility in women (women are not ovulating properly). The main symptom of infertility is the inability to get pregnant, a menstrual cycle that's too long, too short, irregular or absent can mean you're not ovulating.
Can UBIPHENE 100MG TABLET be used in pregnant women?
UBIPHENE 100MG TABLETis not recommended for use in pregnant women or women who are planning to have a baby. Consult your doctor for advice before taking this medicine if you are pregnant or planning to get pregnant.
What if I forget to take a dose of UBIPHENE 100MG TABLET?
You should take UBIPHENE 100MG TABLET immediately when you remember. If it is time for your next dose skip the dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
Can I drive while taking UBIPHENE 100MG TABLET?
Do not drive or use machines while taking UBIPHENE 100MG TABLET as you may have problems with your eyesight causing blurred vision affecting your ability to drive or use machines. Consult your doctor before taking it.
How does UBIPHENE 100MG TABLET work?
UBIPHENE 100MG TABLET contains clomifene which acts by increasing the gonadotrophin hormones secreted by pituitary glands which in turn stimulates the maturation and endocrine activity of the ovarian follicle (stimulates the release of eggs from the ovary). Ubidecarenone protects the body from damage by chemicals that cause infertility.
REFERENCES
1. KD Tripathi. Estrogens, Progestins and Contraceptives. Essentials of medical pharmacology. Eighth Edition. 2019. Page –337
2. Abdelaziz El Refaeey, Amal Selem, Ahmed Badawy. Combined coenzyme Q10 and clomiphene citrate for ovulation induction in clomiphene-citrate-resistant polycystic ovary syndrome. [Revised on March 2014] [Accessed on 30th July 2022] https://www.rbmojournal.com/article/S1472-6483(14)00178-3/fulltext#relatedArticles
3. E Y Kang, J W Choi, H S Gwak, I K Chun. Comparison of bioavailability of two ubidecarenone products in healthy Korean volunteers. [Accessed on 30th July 2022] https://pubmed.ncbi.nlm.nih.gov/19281730/
4. Zentiva k.s. Electronic Medicines Compendium (EMC). [Revised in June 2021] [Accessed on 30th July 2022] https://www.medicines.org.uk/emc/files/pil.961.pdf
5. Magis Pharma S.r.l. Ubidecarenone. [Revised in March 2017] [Accessed on 30th July 2022] https://www.magispharma.it/media/ubicor/download/en/15785752395e172587c8bd2.pdf
AUTHOR DETAILS
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 07 Jan 2023 | 03:41 PM(IST)
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