INTRODUCTION

TRIVEDON MR contain Trimetazidine which belongs to a group of medicine called pFOX (Partial fatty acid oxidation) inhibitors. This medicine is used in combination with other medicines to treat angina pectoris (chest pain caused by coronary disease) in adults. Heart receives reduced oxygen supply during an episode of angina and this medicine protects the heart cells during this condition.

Angina pectoris is a condition marked by severe pain in the chest, often also spreading to the shoulders, arms, and neck, owing to an inadequate blood supply to the heart. Angina is a symptom of coronary artery disease. TRIVEDON MR works by shifting its metabolism from fats to glucose, thus decreasing the oxygen requirement of the heart. As a result, the heart works more efficiently. Along with this medication, quitting smoking, cutting down alcohol intake, eating well, taking regular exercise, and managing stress improves the health of your heart.

The common side effects are dizziness, headache, abdominal pain, diarrhoea, indigestion, nausea, vomiting, rash, itching, hives, and feeling of weakness. This medicine strictly not recommended for use in children and adolescents under 18 years. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.

USES OF TRIVEDON MR

• Treats angina pectoris in adult

HOW TRIVEDON MR WORKS

TRIVEDON MR works by decreases the oxygen requirement of the heart by shifting its metabolism from fats to glucose. As a result, the heart works more efficiently.

DIRECTIONS FOR USE

Always take TRIVEDON MR exactly as your doctor has told you. This medicine must be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF TRIVEDON MR

HOW TO MANAGE SIDE EFFECTS

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Abdominal pain:

Try to rest and relax. Eat and drink slowly and smaller and frequent meals. Applying a heat pad or covered hot water bottle on your stomach may also help. If still pain persists, speak to your doctor.

Diarrhoea:

Drink lot of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without consulting to a doctor.

Nausea and vomiting:

Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor about all the medicines you use, including prescription and non-prescription medicines and herbal supplements.

SYNOPSIS

MORE INFORMATION

Store at room temperature and keep out of reach of children.

FAQs ABOUT TRIVEDON MR

Can TRIVEDON MR be used in elderly patients?

It should be used with caution in patients aged more than 75 years of age. Usually, a lower dose is prescribed in elderly patients to reduce the chances of adverse effects. It is important to continuously monitor such patients.

Does TRIVEDON MR cause drowsiness?

Yes, it may make you feel dizzy and drowsy. Therefore, you should avoid driving or using heavy machinery in case it causes these side effects.

REFERENCES

1. KD Tripathi. Antianginal and Other Anti-ischaemic Drugs. Essentials of Medical Pharmacology. Seventh Edition,2013. Page-553-554.

2. K J McClellan 1, G L Plosker. Trimetazidine. A review of its use instable angina pectoris and other coronary conditions. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov.Jul 1999. [Accessed 17 Nov 2020] https://pubmed.ncbi.nlm.nih.gov/10439934/

3. VIANEX S.A; Electronic Medicines Compendium (EMC) [Revised on Apr 2016] [Accessed 17 Nov 2020] https://www.hpra.ie/img/uploaded/swedocuments/2175323.PPA0465_122_001.7fe02c5a-e650-4c76-9bbe-6ed7fb2b4ef6.000001Vastarel%2020mg%20Tabs%20PIL.160425.pdf