TRIOLMESAR 20mg Tablet 10's

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Amlodipine Besylate 5mg+Hydrochlorothiazide 12.5mg+Olmesartan 20mg
By Macleods Pharmaceuticals Pvt Ltd
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Drug Information for TRIOLMESAR 20mg Tablet 10's

What is TRIOLMESAR 20mg Tablet used for?

TRIOLMESAR 20mg Tablet is used in the treatment of hypertension (high blood pressure) in patients who are already taking either

  • a fixed dose combination of Amlodipine + Olmesartan Medoxomil;
  • a fixed dose combination of Olmesartan Medoxomil + Hydrochlorothiazide with Amlodipine as a single tablet;
  • a fixed dose combination of Amlodipine Besylate + Olmesartan Medoxomil with Hydrochlorothiazide as a single tablet

TRIOLMESAR 20mg Tablet may also be prescribed for other conditions as determined by your doctor.

How does TRIOLMESAR 20mg Tablet work?

  • Amlodipine Besylate belongs to a group of medicines known as calcium channel blockers. Amlodipine Besylate prevents the calcium from moving into the blood vessel wall thereby preventing tightening of blood vessel walls. This reduces the blood pressure and improves symptoms of chest pain.
  • Olmesartan Medoxomil belongs to a group of medicines known as angiotensin II receptor antagonist. Olmesartan relaxes the blood vessel walls, thus reducing the blood pressure.
  • Hydrochlorothiazide belongs to group of medicines called thiazide diuretics also known as “water tablets”. It removes excess fluid by making the kidney produce more urine, thereby reducing the blood pressure.

TRIOLMESAR 20mg Tablet act additively to reduce the blood pressure.

How to take TRIOLMESAR 20mg Tablet?

  • The dosage of oral tablets of TRIOLMESAR 20mg Tablet depends on the age, weight and medical condition of an individual. Take TRIOLMESAR 20mg Tablet as prescribed by your doctor.
  • You must swallow the tablet with a glass of water. Do not chew the tablet.
  • Take your daily dose at same time (preferably at breakfast).
  • Do not take the tablet with grapefruit juice (it can lead to increase in amlodipine concentration which would increase the lowering of the blood pressure).
  • If you are taking other cholesterol lowering drugs, take TRIOLMESAR 20mg Tablet, 4 hours before taking these medications
  • TRIOLMESAR 20mg Tablet is not recommended for children and adolescent under 18 years of age.
  • Do not discontinue the medication without consulting a doctor.
  • If you miss a dose of TRIOLMESAR 20mg Tablet, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

If you have taken an overdose of TRIOLMESAR 20mg Tablet, please contact your doctor immediately.

Symptoms of overdose may include the following:

  • Dizziness
  • Fast or slow heart rate
  • Hypotension

What are the drugs that interact with TRIOLMESAR 20mg Tablet?

Drugs that interact with TRIOLMESAR 20mg Tablet:

  • Aliskiren
  • Amantadine
  • Antidepressants
  • Atropine, Biperiden
  • Baclofen, Tubocurarine
  • Calcium supplements
  • Cyclosporin, Tacrolimus
  • Cisapride
  • Colesevelam
  • Dantrolene
  • Diphemanil
  • Diltiazem, Verapamil
  • Erythromycin, Clarithromycin, Rifampicin
  • Halofantrine
  • Ketoconazole, Itraconazole
  • Lithium
  • Other medicines for treatment of high blood pressure
  • Potassium supplements and salt substitutes containing potassium
  • Simvastatin
  • NSAIDs (non-steroid anti-inflammatory drugs)
  • St John's wort

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of TRIOLMESAR 20mg Tablet?

Most common side effects of TRIOLMESAR 20mg Tablet are:

  • Upper respiratory tract infection
  • Sore throat and nose
  • Urinary tract infection, urge to pass urine
  • Dizziness
  • Headache
  • Awareness of heartbeat, low blood pressure
  • Nausea, diarrhoea, constipation, cramps
  • Joint swelling, ankle swelling
  • Tiredness

Please contact your physician immediately if you have

  • allergic reactions (swelling of the face, mouth, larynx (voice box), itching and rash);
  • severe light-headedness or fainting;
  • persistent diarrhoea which causes weight loss;
  • decrease in vision;
  • angioneurotic oedema (red, burning, itching areas on skin near eyes, lips, hands, feet and inside of throat, hoarseness of voice, difficulty in breathing);
  • low levels of serum potassium;
  • severe skin allergies such as blisters on skin, mouth, lips, eyes and genitals (commonly called Steven Johnsons syndrome).

This is not a comprehensive list of side effects. Consult your doctor to know more about other possible side effects.

What special precautions TRIOLMESAR 20mg Tablet?

Seek doctor’s advice before taking any other drug or herbal products while on TRIOLMESAR 20mg Tablet.

You are advised not to take TRIOLMESAR 20mg Tablet if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking TRIOLMESAR 20mg Tablet?

Tell your doctor if

  • you are allergic to TRIOLMESAR 20mg Tablet or to any ingredients of this medicine.
  • you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • you have diabetes related kidney problem.
  • you are taking an ACE inhibitor (Enalapril, Lisinopril, Ramipril).
  • you are taking any medicine containing Aliskiren.
  • you have diabetes.
  • you have a previous history of angioedema.
  • you are under dialysis.
  • you have renal artery stenosis (narrowed blood vessel in kidney) or have had a kidney transplant.
  • you have liver disease.
  • you have a heart disease or problem with valves and muscles of your heart.
  • you are on low salt diet.
  • your blood potassium levels are low.
  • you have a poor functioning adrenal gland.
  • you have systemic lupus erythematosus (SLE) (an autoimmune disease).
  • you have asthma.
  • you have skin rash after being in the sun or using a sunbed.
  • you are planning a surgery or any procedure.
  • you are pregnant or trying to conceive or are breastfeeding.

What should you do when you have taken an overdose of TRIOLMESAR 20mg Tablet?

If you have taken an overdose of TRIOLMESAR 20mg Tablet, please contact your doctor immediately.

Symptoms of overdose may include the following:

  • Dizziness
  • Fast or slow heart rate
  • Hypotension

Frequently Asked Questions about TRIOLMESAR 20mg Tablet

  1. How should TRIOLMESAR 20mg Tablet be stored?
  2. TRIOLMESAR 20mg Tablet does not require any special storage conditions. Keep the medicine away from sunlight and do not freeze the medicine. Keep the medicine out of reach from children.

  3. Can I drive while taking TRIOLMESAR 20mg Tablet?

  4. TRIOLMESAR 20mg Tablet causes drowsiness, dizziness and headache and affects the driving ability. Avoid driving if you are taking Amlodipine Besylate + Hydrochlorothiazide + Olmesartan.

  5. Should I follow any special dietary instructions while taking TRIOLMESAR 20mg Tablet?
  6. Do not take grapefruit or grapefruit juice while on TRIOLMESAR 20mg Tablet. Apart from this, there are no dietary restrictions if you are taking Amlodipine besylate + Hydrochlorothiazide + Olmesartan Medoxomil.

  7. Can I drink alcohol while taking Amlodipine Besylate + Olmesartan?

  8. No, it is not advisable to consume alcohol while on TRIOLMESAR 20mg Tablet as it can make you dizzy, sleepy or tired.

  9. Is TRIOLMESAR 20mg Tablet addictive?
  10. No, TRIOLMESAR 20mg Tablet is not addictive. However, do not take it without consulting your doctor.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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