Testoviron Depot 250 Injection 1ml

Introduction About TESTOVIRON DEPOT 250 INJECTION

Testoviron Depot 250 Injection is a testosterone replacement therapy used for managing male hypogonadism and low testosterone levels and associated signs like delayed puberty in boys, impotence, low bone mineral density, fatigue, feeling low or depression and low muscle mass in men who have underlying medical conditions.

It contains an active ingredient called testosterone enanthate, a synthetic form of testosterone (male sex hormone), designed to manage low testosterone levels in men. It helps restore normal hormonal balance, improving symptoms like fatigue, low libido, and loss of muscle mass. Administered via intramuscular injection skin under a doctor's supervision, it provides long-lasting effects.

Your doctor will determine the correct dosage based on your condition. Always inform your doctor about any pre-existing conditions and other medications you are taking. Regular blood tests are recommended to monitor testosterone and PSA levels.

Common side effects of testoviron injection include swelling, rapid weight gain, coughing, and injection site reactions like pain or redness. Serious side effects may require discontinuation of the medication, such as breathing difficulties or persistent erections.

Uses Of TESTOVIRON DEPOT 250 INJECTION

• Low Testosterone levels
• Male hypogonadism

Post marketing experience of FDA suggest that Testosterone products are FDA-approved only for use in men who lack or have low testosterone levels in conjunction with an associated medical condition such as failure of the testicles to produce testosterone due to genetic problems or chemotherapy, or problems with brain structures (pituitary related hormonal imbalance).

Benefits of Testoviron Injection for men:

1. Boosts Testosterone Levels Naturally

Testoviron Depot 250 provides a reliable source of testosterone for men with hypogonadism (low testosterone levels), helping restore hormonal balance effectively. By addressing testosterone deficiency, testosterone helps improve sexual health, including impotence, libido and erectile function.

2. Improves Muscle Strength and Mass

Clinical studies have shown that testosterone injection is known to enhance protein synthesis in the body, promoting muscle growth and improving overall strength, making it beneficial for fitness enthusiasts and athletes with medical needs.

3. Supports Bone Health:

Testosterone plays a key role in maintaining bone density. This injection helps reduce the risk of osteoporosis and strengthens bones over time.

4. Boosts Energy Levels and Mood

Studies have shown that low testosterone levels are often associated with fatigue and depression. Testoviron Depot 250 injection can elevate mood, enhance energy levels, and reduce symptoms of lethargy.

5. Improves Red Blood Cell Production

Testosterone stimulates red blood cell production, which may help combat anemia and improve oxygen supply throughout the body.

How to use TESTOVIRON DEPOT 250 INJECTION

Testoviron Depot Injection will be given to you only by a doctor or a nurse in hospital or clinics.

How to Use Testoviron Injection:

• Testoviron Depot 250 Injection is designed for intramuscular administration (into the muscles) and should only be given by a trained healthcare professional.
• The dosage and frequency are determined by your doctor based on your condition and hormone levels.
• Typically, it is administered every 2-3 weeks. The injections are continued for as long as your doctor considers necessary, depending on your individual health needs.
• Men receiving long term therapy may later be given injections at 3-to-6-week intervals.
• Never attempt to self-administer this injection, as improper administration can lead to complications.

Testoviron Dosage for Low Testosterone:

The dosage for managing low testosterone with Testoviron Depot 250 Injection generally ranges from 250 mg every 2-4 weeks, depending on the severity of testosterone deficiency and your doctor’s recommendation. Regular monitoring of testosterone levels is essential to adjust the dosage for optimal results.

Testoviron Dosage for Bodybuilding:

For bodybuilding purposes, testosterone injections are sometimes misused to enhance muscle growth and strength. However, such usage is off-label and not medically recommended. Misuse of testosterone injections can lead to serious side effects like hormonal imbalance, liver damage, and cardiovascular risks. Therefore, proper health consultation and careful monitoring of testosterone levels are required.

Testoviron Dosage for Testosterone Replacement Therapy (TRT)

In Testosterone Replacement Therapy (TRT), the typical dose of Testoviron Depot 250 is 100-250 mg administered every 2-4 weeks. Your doctor may adjust the dosage based on your blood testosterone levels and symptoms. This therapy helps restore hormonal balance in men with hypogonadism.

Testoviron Depot 250 Injection Cycle Duration:

The typical cycle duration for Testoviron Depot 250 depends on the medical condition being treated. For testosterone replacement therapy, cycles may last several months to years under a doctor's supervision.

What Happens if I Overdose on Testoviron Injection?

Overdosing on Testoviron Depot 250 can lead to serious side effects such as severe hormonal imbalance, liver damage, acne, mood swings, and water retention. Prolonged overdosing may increase the risk of cardiovascular problems or gynecomastia (breast tissue enlargement in men). If you suspect an overdose, seek immediate medical attention to prevent complications.

Side Effects Of TESTOVIRON DEPOT 250 INJECTION

Like all medicines, Testoviron Depot injection may cause certain certain side effects, although not everybody gets them.

Common side effects of Testoviron Injection:

• pain at the injection site
• acne
• mood changes
• changes in libido.
• increased red blood cells and haemoglobin
• weight gain

When to consult your doctor?

Contact your doctor immediately if you experience any of the following symptoms after receiving testosterone injections.

Signs of allergic reaction (such as swelling of face, lips, eyes, nose, skin rashes with hives, itching and difficulty in breathing or swallowing)

• Sudden nausea, vomiting with body itching and yellowing of eyes and body with stomach discomfort and pain – signs of liver problem
• Suspect blood clot formation in blood vessels, which can be cause symptoms like painful swelling of one leg, sudden change in colour (paleness or bluish discoloration) of the skin, sudden breathlessness, sudden cough with or without blood, sudden chest pain, dizziness, severe light headedness, severe stomach pain, or sudden loss of vision

Testoviron and risk of gynecomastia:

• Testoviron Depot 250 can sometimes lead to gynecomastia (enlargement of male breast tissue) due to the conversion of excess testosterone into estrogen, a process called aromatization.
• This risk is higher with improper dosages or prolonged use. Symptoms may include tenderness, swelling, or breast tissue enlargement.
• To prevent gynecomastia, it’s important to follow the prescribed dosage and consult your doctor for regular monitoring. If you notice any symptoms, seek medical advice promptly.

How To Manage Side Effects

Acne:

• Cleanse gently: Wash your face twice daily with a mild, non-comedogenic cleanser to remove excess oil and dirt.
• Topical treatments: Apply benzoyl peroxide or salicylic acid to acne-prone areas to reduce inflammation and prevent new breakouts.
• Avoid touching your face: This prevents bacteria and oils from spreading and exacerbating acne.
• Stay hydrated: Drinking plenty of water helps keep skin healthy and reduces oil production.
• Consult your doctor: If acne persists, discuss possible dosage adjustments or additional treatments.

Mood Swings:

• Stay active: Regular exercise, especially aerobic activities like walking or running, can help stabilize mood.
• Practice mindfulness: Deep breathing, meditation, or yoga can reduce stress and improve emotional well-being.
• Get adequate sleep: A consistent sleep schedule supports emotional balance.
• Eat a balanced diet: Include foods that boost mood, such as whole grains, fruits, and vegetables.
• Track emotional changes: Keeping a journal can help identify triggers, allowing you to adjust lifestyle or discuss them with your doctor.

Warning & Precautions

Pregnancy

Contraindicated

Testosterone injection is intended exclusively for men. It is unsafe for use in pregnant women due to the potential risk of virilization (development of male characteristics) in the female fetus. Please consult your doctor before receiving it.

Breastfeeding

Contraindicated

Testosterone injection is unsafe for use during breastfeeding, as there is evidence indicating it may pose a risk of toxicity to the baby. Additionally, this medication is not intended for use in women. Please consult your doctor before receiving it.

Driving and Using Machines

Safe

 Testoviron injection does not affect your ability to drive or use machinery.

Alcohol

Use with Caution

It is recommended to be cautious when drinking alcohol while receiving Testoviron injection  as it may reduce its effectiveness.

Kidney

Contraindicated

Testoviron injection is not safe for individuals with kidney disease and should be avoided. Therefore, inform your doctor if you have any pre-existing kidney diseases as a precaution. Consult your doctor before use.

Liver

Contraindicated

Testoviron injections are probably unsafe for patients with liver disease and should be avoided. Regular check-ups and blood tests are necessary for these patients. Make sure to inform your doctor if you have any liver conditions as a precaution.

Allergy

Contraindicated

Do not receive Testoviron if you are allergic to Testosterone and/or any other ingredients of this medicine.

Heart Disease

Use with Caution

Testoviron should be used with caution in patients with high blood pressure. Inform your doctor if you have severe heart disease as this medicine may cause water retention in the body accompanied by congestive heart failure. Consult your doctor before use.

Use In Pediatrics

Contraindicated

Testoviron Depot Injection is unsafe for use in children and adolescents (aged below 18 years) as safety and efficacy have not been established. Consult your doctor before receiving it.

Use In Geriatrics

Use with Caution

Testoviron Depot Injection should be used with caution in elderly patients (aged 65 years and above) due to increased risk of prostate cancer or enlargement of prostate gland. Consult your doctor before receiving it.

Safety Advice

Testoviron Depot 250 and Long-Term Health Risks:

Prolonged testosterone therapy may increase the likelihood of cardiovascular problems, such as high blood pressure, heart attack, or stroke, particularly in individuals with pre-existing heart conditions. Additionally, extended use can lead to liver damage, sleep apnea, and infertility. Monitoring by a healthcare professional is essential for early detection of these risks, ensuring safe and effective treatment.

Expert Advice on Using Testoviron for Low Testosterone:

• Consult your doctor regularly: Regular monitoring of testosterone levels is crucial for adjusting the dosage.
• Follow prescribed dosage: Adhere strictly to the recommended dose to minimize risks and side effects.
• Lifestyle support: Complement treatment with a healthy diet, exercise, and adequate sleep.
• Report side effects: Notify your doctor of any unusual symptoms like mood swings or skin issues.
• Long-term commitment: Consistent use is often necessary, and periodic check-ups ensure the therapy is effective.

Testoviron Depot 250 Injection: Reviews & Ratings:

Testosterone therapy has been reported to significantly improve energy, libido, muscle mass, and mental clarity in individuals with low testosterone levels. Many users experience a positive turnaround in strength and vitality, particularly in their sexual health and physical performance. However, results can vary, and finding the correct dosage is crucial for optimal benefits. Some individuals may need adjustments to their dosage to achieve the best outcomes. It's essential to monitor free testosterone levels for maximum effectiveness. For more detailed user experiences, you can explore further on Drugs.com.

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Drug - Drug interaction

Inform your physician if you are taking any of the following medicine before receiving Testoviron Depot Injection:

• Anticoagulants (e.g., Warfarin, Coumadin)
• Insulin and Oral Hypoglycemics
• Corticosteroids (e.g., Prednisone)
• Cytochrome P450 Enzyme Inhibitors (e.g., Ketoconazole, Cimetidine)
• Propranolol and Other Beta-Blockers
• Anticonvulsants (e.g., Phenytoin, Carbamazepine)
• HIV Protease Inhibitors (e.g., Ritonavir, Atazanavir)
• Opiates (e.g., Morphine, Oxycodone)

Drug - Food interaction

Food and Drink Restrictions While Taking Testosterone Replacement Therapy:

• Alcohol: Avoid consuming alcohol, as it can increase the risk of liver damage.
• High-fat foods: A diet high in fat may affect testosterone metabolism, so a balanced diet is recommended.

Synopsis

More Information

Diet, Exercise, and Lifestyle Advice:

• Follow a balanced diet: Include protein-rich foods, healthy fats, and vegetables to support muscle growth.
• Stay hydrated: Drink plenty of water throughout the day.
• Engage in strength training: Focus on weightlifting and resistance exercises to boost muscle mass.
• Incorporate cardio: Add aerobic exercises like walking or cycling for overall health.
• Prioritize sleep and recovery: Ensure 7-9 hours of sleep to support recovery and hormone balance. 
• Avoid processed foods and excessive alcohol: They may hinder the benefits of testosterone therapy.

What to Avoid When on Testosterone Replacement Therapy

• Excessive alcohol: Limit alcohol intake as it can affect liver function and hinder testosterone effectiveness.
• High-stress levels: Chronic stress can interfere with hormone balance and overall well-being. Practice stress management techniques like meditation or deep breathing.
• Poor sleep: Aim for 7-9 hours of quality sleep to optimize testosterone production and recovery.
• Unhealthy eating habits: Avoid processed foods and excessive sugar to prevent weight gain, which can impact hormone therapy results.

Testoviron Depot 250 vs. Sustanon 250 Injection:

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FAQs About TESTOVIRON DEPOT 250 INJECTION

References

1. Testosterone Enantate 250mg/ ml Solution for Injection. EMC. UK. [Revised in November 2022]. [Accessed on 7th January 2025]. Click here
2. Testosterone Information. Post-marketing Drug Safety Information. U.S. Food and Drug Administration. March 2015. [Accessed on 7th January 2025]. Click here
3. Effects of lifelong testosterone exposure on health and disease using Mendelian randomization. PMC. PubMed Central. National Library of Medicine. [Accessed on 7th January 2025]. Click here
4. The benefits and risks of testosterone replacement therapy: a review. PMC. PubMed Central. National Library of Medicine. June 2009 [Accessed on 7th January 2025]. Click here
5. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 299.

Useful Diagnostic Tests

• Testosterone - Total

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. M N Himaja - MBBS

Last updated on 08 Jan 2025 | 10:16 AM(IST)