New Revised MRP, 100% GST benefit passed Tenvir AF 25mg Tablet 30'S
Netmeds First Membership
Quick Links
Introduction About TENVIR AF 25MG TABLET
TENVIR AF 25MG TABLET contains Tenofovir alafenamide which belongs to the group of medicines called Anti-viral drugs. It is used to manage chronic (long-term) hepatitis B infection in adolescents and adults (aged 12 years and older). Hepatitis B is a virus that infects the liver, causes long-term infection, and can result in liver damage. It can show symptoms like easy tiredness, anxiety, lack of appetite, jaundice, fits and vomiting.
Before taking TENVIR AF 25MG TABLET, inform your doctor if you have any liver or kidney disease, hepatitis C or D (viral liver infection), HIV infection, intolerance to some sugars. TENVIR AF 25MG TABLET should be used with caution in pregnant women and it is not recommended for use in breastfeeding women.
Prior to the management, your doctor may want you to take several blood tests to understand your existing condition. During the management take precautions to avoid sexual contact and spreading the infection to others.
TENVIR AF 25MG TABLET is not recommended for use in children who are (younger than 12 years of age or weighing less than 35 kgs) and it should be used with caution in elderly patients (aged 65 years and above). The most common side effects of taking TENVIR AF 25MG TABLET are headache, diarrhoea, vomiting, nausea, dizziness, stomach pain, joint pain, rash, itching and tiredness. Consult your doctor if any of the side effect worsens
Uses Of TENVIR AF 25MG TABLET
- Manage long-term hepatitis B infection
How TENVIR AF 25MG TABLET Works
TENVIR AF 25MG TABLET works by inhibiting an enzyme (viral polymerase), causing chain termination, which in turn, inhibits DNA synthesis and viral replication, thereby managing the virus to produce new viruses and stops the infection from spreading.
How to use TENVIR AF 25MG TABLET
Take TENVIR AF 25MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Your doctor will decide the right dose and duration depending upon your age, body weight and disease condition. Do not stop taking TENVIR AF 25MG TABLET unless your doctor advices to stop.
Side Effects Of TENVIR AF 25MG TABLET
Common
- headache, dizziness
- diarrhoea, vomiting, nausea, stomach pain, feeling bloated, flatulence
- joint pain
- rash, itching
- tiredness
Uncommon
- swelling of the face, lips, throat or tongue (angioedema)
- hives (urticaria)
- increased liver enzyme in the blood
Rare
Stop taking TENVIR AF 25MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- new onset or worsening of kidney impairment
- lactic acidosis (too much acid in the blood) (signs include weakness or tiredness than usual, unusual muscle pain, shortness of breath or fast breathing, stomach pain with nausea and vomiting, fast or abnormal heartbeat, cold or blue hands and feet, feeling dizzy or light-headedness)
- signs of severe liver problems (such as yellowing of skin or white of the eyes, dark tea-colored urine, light-colored stools, loss of appetite, stomach pain or nausea)
How To Manage Side Effects
Diarrhea
Drink lot of water or fruit juice to keep yourself hydrated. Avoid eating high-fat or spicy foods. if symptoms does not show improvement consult your doctor.
Dizziness Or Drowsiness
Lie down until dizziness is gone. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol, and drugs. If symptom does not show improvement, consult your doctor.
Headache
Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not show improvement.
Indigestion
Eat smaller and frequent meals and exercise regularly (walking). Limit the intake of carbonated drinks. Avoid eating foods such as beans, lentils which cause bloating. If the symptom does not show improvement, consult your doctor.
Nausea And Vomiting
Take TENVIR AF 25MG TABLET with meals. Stick to simple meals. Avoid eating oily, fried or spicy foods. Do not lay down or sleep immediately after eating. If symptom does not show improvement, consult your doctor.
Stomach Pain
Try to rest and relax. Have smaller meals more frequently. Keep a heat pad. If the symptom does not show improvement, consult your doctor.
Warning & Precautions
Pregnancy
Monitoring requiredTENVIR AF 25MG TABLET should be used with caution during pregnancy only if considered clearly necessary. Consult your doctor before taking TENVIR AF 25MG TABLET.
Breastfeeding
ContraindicatedTENVIR AF 25MG TABLET is not recommended for use in breastfeeding women as the medicine passes to baby through breast milk. Consult your doctor before taking TENVIR AF 25MG TABLET.
Driving and Using Machines
Use with CautionDo not drive or use any machines if you feel dizzy after taking TENVIR AF 25MG TABLET.
Kidney
Use with CautionTENVIR AF 25MG TABLET should be used with caution in patients with kidney disease or problems. Consult your doctor before taking TENVIR AF 25MG TABLET.
Liver
Use with CautionTENVIR AF 25MG TABLET should be used with caution in patients with history of liver disease, including hepatitis C or D (viral liver infection that leads to serious liver damage). Consult your doctor before taking TENVIR AF 25MG TABLET.
Allergy
ContraindicatedDo not take TENVIR AF 25MG TABLET if you are allergic to Tenofovir alafenamide or any other ingredients of this medicine.
Use In Pediatrics
ContraindicatedTENVIR AF 25MG TABLET is not recommended for use in children who are (younger than 12 years of age or weighing less than 35 kgs). Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionTENVIR AF 25MG TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking TENVIR AF 25MG TABLET.
Others
Before taking TENVIR AF 25MG TABLET, inform your doctor if you have:
- HIV (human immunodeficiency virus) infection
- intolerance to some sugars
Interactions
A. Drug-Drug interactions:
Before taking TENVIR AF 25MG TABLET, inform your doctor if you are taking any of the following medicines:
- other medicines used to manage hepatitis B infection (Ex. tenofovir alafenamide, tenofovir disoproxil, adefovir dipivoxil)
- ritonavir or cobicistat boosted darunavir, lopinavir, atazanavir (used to manage HIV infection)
- medicines used to manage bacterial infections including tuberculosis (Ex. rifabutin, rifampicin, rifapentine)
- medicines used to manage fits (Ex. carbamazepine, oxcarbazepine, phenobarbital or phenytoin)
- St. John’s wort (herbal medicine for depression and anxiety)
- medicines used to manage fungal infections (Ex. ketoconazole or itraconazole)
Overdose:
If you or anyone else accidentally take too much of TENVIR AF 25MG TABLET, consult your doctor immediately or visit the nearby hospital due to increased risk of side effects.
Synopsis
| Drug | : | Tenofovir alafenamide |
| Pharmacological Category | : |
Nucleotide Reverse Transcriptase Inhibitor (NtRTI) |
| Therapeutic Indication | : | Hepatitis B infection |
| Dosage Forms | : | Tablet |
More Information
- Keep TENVIR AF 25MG TABLET away from children
- Store at room temperature
FAQs About TENVIR AF 25MG TABLET
Q: Can I pass hepatitis B infection to others while taking TENVIR AF 25MG TABLET?
A: Yes, you can still pass the infection to others while taking TENVIR AF 25MG TABLET. It does not reduce the risk of infecting others with hepatitis B through sexual contact or blood contamination. Discuss the precautionary measures needed with your doctor to avoid infecting others.
Q: What if I miss a dose of TENVIR AF 25MG TABLET?
A: It is important not to miss a dose of TENVIR AF 25MG TABLET but if you do, take the next dose as soon as possible if you remember within 18 hours of previous dose. Do not take the forgotten dose if you remember after 18 hours or more of previous dose. Wait and take your next dose as per schedule.
Q: What if I vomit a dose of TENVIR AF 25MG TABLET?
A: If you have vomited a dose of TENVIR AF 25MG TABLET in less than 1 hour after taking it, take another medicine. Do not take another dose if you vomit the medicine more than 1 hour after taking it.
Q: Can I stop taking TENVIR AF 25MG TABLET?
A: Do not stop taking TENVIR AF 25MG TABLET without consulting your doctor, as it may worsen your condition. It could be very serious if you already have any liver problems. When you stop taking TENVIR AF 25MG TABLET, your doctor will monitor you for several months to check your infection. If you have any more doubts regarding the use of this medicine, ask your doctor.
Q: Can TENVIR AF 25MG TABLET be used in children?
A: No, TENVIR AF 25MG TABLET is used for adults and not recommended for use in children who are (younger than 12 years of age or weighing less than 35 kgs). Child’s doctor will decide the correct dose or select a suitable alternative therapy for your child.
References
1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Hepatitis, viral. Pharmacotherapy Handbook. Ninth edition. Page- 217.
2. Lesley J. Scott, Henry L. Y. Chan. Tenofovir alafenamide- A review in chronic hepatitis B. Drugs. Springer Link. [Revised in June 2017]. [Accessed on 25th June 2022] https://link.springer.com/article/10.1007/s40265-017-0754-9
3. Adrian S Ray, Marshall W Fordyce, Michael J M Hitchcock. Tenofovir alafenamide: A novel prodrug of tenofovir for the treatment of Human Immunodeficiency Virus. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. January 2016. [Accessed on 25th June 2022] https://pubmed.ncbi.nlm.nih.gov/26640223/
4. Gilead Sciences Ireland UC. Electronic Medicines Compendium (EMC). [Revised in January 2021] [Accessed on 25th June 2022] https://www.medicines.org.uk/emc/files/pil.2314.pdf
5. Gilead Sciences, Inc. U.S. Food & Drug Administration. [Revised in April 2020] [Accessed on 25th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208464s008lbl.pdf
Useful Diagnostic Tests
- Hepatitis B panel of blood tests
- Liver Function Test
- Complete Blood Count (CBC)
Author Details
