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INTRODUCTION
TADACT 20MG contains Tadalafil which belongs to a group of medicines called phosphodiesterase type 5 inhibitors. It is used to treat adult men with erectile dysfunction and symptoms of benign prostatic hyperplasia (ED/BPH) also used to manage pulmonary arterial hypertension. This medicine significantly improves the ability of obtaining a hard erect penis suitable for sexual activity. It works by helping the blood vessels in penis to relax, allowing the flow of blood into penis.
It is not indicated for women. Not suitable for use by children and adolescents under the age of 18 years. The common side effects of this medicine are headache, muscle pain and rash. Do not take this medicine if you have severe heart, liver problems or low blood pressure. Avoid driving and drinking alcohol while taking this medicine since it may cause dizziness.
USES OF TADACT 20MG
- Treat adult men with erectile dysfunction and symptoms of benign prostatic hyperplasia (ED/BPH)
- Manage pulmonary arterial hypertension
HOW TADACT 20MG WORKS
TADACT 20MG works by helping the blood vessels in penis to relax, allowing the flow of blood into penis.
DIRECTIONS FOR USE
Take this medicine according to the dose and frequency as advised by your doctor. Swallow it as a whole. It can be taken with or without food.
SIDE EFFECTS OF TADACT 20MG
SERIOUS
- allergic reactions like rashes
- chest pain
- priapism
- sudden loss of vision
COMMON
- headache
- back pain
- muscle aches
- pain in arms and legs
- facial flushing
- nasal congestion
- indigestion
RARE
- fainting, seizures, memory loss, swelling of the eyelids, red eyes
- decrease or loss of hearing, hives, penile bleeding
- blood in semen and increased sweating
HOW TO MANAGE SIDE EFFECTS
Indigestion:
Stick to simple normal meals and do not eat rich or spicy foods.
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
WARNING & PRECAUTIONS
PREGNANCY
TADACT 20MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
TADACT 20MG is not recommended for use in breastfeeding women. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or handle any machines while taking this medicine it may cause dizziness.
ALCOHOL
Consumption of alcohol is not recommended during treatment with TADACT 20MG, since this may increase the risk of dizziness.
KIDNEY
TADACT 20MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
LIVER
TADACT 20MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.
ALLERGY
Do not take if you are allergic (hypersensitive) to Tadalafil.
HEART DISEASE
TADACT 20MG is not recommended if you have serious heart disease or recently had a heart attack. Consult your doctor for advice.
OTHERS
Inform your doctor if you have or had,
- low blood pressure or uncontrolled high blood pressure
- sickle cell anaemia
- multiple myeloma (cancer of the bone marrow)
- leukaemia (cancer of the blood cells)
- any deformation of penis
INTERACTIONS
Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,
- nitrates
- alpha blocker (used to treat high blood pressure or urinary symptoms associated with benign prostatic hyperplasia)
- riociguat (used to treat pulmonary arterial hypertension)
- 5- alpha reductase inhibitor (used to treat benign prostatic hyperplasia)
- ketoconazole (used to treat fungal infections)
- protease inhibitors (used for AIDS or HIV infection)
- phenobarbital, phenytoin and carbamazepine (used to treat seizures)
- rifampicin, erythromycin, clarithromycin or itraconazole
- other treatments for erectile dysfunction
SYNOPSIS
| Drug | : | Tadalafil |
| Pharmacological Category | : | Phosphodiesterase-5 Enzyme Inhibitor |
| Therapeutic Indication | : | Benign prostatic hyperplasia, Erectile dysfunction, Pulmonary arterial hypertension |
| Dosage Forms | : | Tablet, Oral disintegrating stips, sachet |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
REFERENCES
1. KD Tripathi MD. Hormones and related drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 304.
2. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page -752-753.
3. Robert M Coward and Culley C Carson. Tadalafil in the treatment of erectile dysfunction. Therapeutics and clinical risk management, Dec 2008; [Accessed Oct 31st 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643112/
4. Accord Healthcare Limited, Electronic Medicines Compendium (EMC); [Revised on Nov 2019] [Accessed Oct 31st 2020] https://www.medicines.org.uk/emc/files/pil.8637.pdf
5. Ciplamed; Sep 16 2016 [Accessed Oct 31st 2020] https://www.ciplamed.com/printpdf/32582
6. Eli Lilly and Company Limited, Electronic Medicines Compendium (EMC); [Revised on Feb 2017] [Accessed Oct 31st 2020] https://www.medicines.org.uk/emc/files/pil.7431.pdf
7. Eli Lilly and Company Limited, Electronic Medicines Compendium (EMC); [Revised on Feb 2017] [Accessed Oct 31st 2020] https://www.medicines.org.uk/emc/files/pil.6747.pdf
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