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Introduction About STARIZO 200 TABLET
Tedizolid 200 mg is indicated for the management of Acute bacterial skin and skin-structure infections (ABSSSIs) in adults and adolescents 12 year age and older.
The usual adult regimen is 200 mg once daily for 6 days. Tablets may be taken with or without food. Follow the exact instructions given by your healthcare professional
Inform your prescriber about all current medicines (including herbal supplements), especially serotonergic agents and medicines that affect blood cells or bone marrow. Report history of blood disorders or nerve problems before starting a course. No routine dose adjustment is usually necessary for mild-to-moderate kidney or liver impairment.
Pregnancy & breastfeeding: discuss potential risks and benefits with your healthcare professional.
Some people may notice nausea, headache, or changes in blood counts. Any new unexplained symptoms, prolonged fever, or easy bruising should be checked by a healthcare professional promptly. Follow lab monitoring if advised by your prescriber.
Key Composition
- Tedizolid Phosphate (200 mg per tablet)
Uses Of STARIZO 200 TABLET
- Manages Acute bacterial skin and skin-structure infections (ABSSSIs)
Benefits of STARIZO 200 TABLET
- Easy-to-swallow capsule/tablet for everyday use
- Offers convenience with once-daily or doctor-directed usage
- Helps maintain comfort throughout the day based on its release profile
- Reduced dosing frequency helps maintain routine
- Ideal for people needing consistent daily support
- Suitable for individuals who require gentle stomach support
How STARIZO 200 TABLET Works
This medicine works by targeting the specific problem that causes the infection in your body. After you take the tablet, it gets absorbed into your bloodstream and reaches the affected area. Once it reaches the infection site, it enters the harmful organisms responsible for causing the illness.
Inside these organisms, the medicine blocks the essential steps they need to grow and multiply. It interferes with their internal processes, stopping them from producing the proteins and structures required for survival. Because of this, the infection-causing organisms weaken, stop multiplying, and eventually die off.
As the number of harmful organisms decreases, your body’s natural defense system becomes more effective at clearing the remaining infection. This helps reduce symptoms and supports your recovery. The medicine is designed to work in a targeted way, so it focuses mainly on the organisms causing the infection without affecting your healthy cells.
How to use STARIZO 200 TABLET
How should I take STARIZO 200 Tablet?
Take STARIZO 200 Tablet exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet. Try to take it at the same time every day to maintain steady levels in your body.
STARIZO 200 Tablet dosage for adults
The usual recommended dose for adults is 200 mg once daily, or as directed by a healthcare professional. Duration depends on the type and severity of infection.
Can I take STARIZO 200 after food?
Yes. STARIZO 200 can be taken with or without food. Food does not affect its absorption.
How many times a day should I take STARIZO 200?
It is usually taken once a day. Only take it as advised by your doctor.
Is STARIZO 200 to be taken with water?
Yes. Swallow the tablet with a full glass of water for easier intake.
STARIZO 200 morning or night dose?
You may take it at any time of the day, but it should be taken at the same time every day. Choose a time that is easy to remember morning or night is both acceptable.
What if I forgot to take STARIZO 200 TABLET
If you miss a dose, take it as soon as you remember.
If it is almost time for your next scheduled dose, skip the missed dose.
Do not take two doses at the same time to make up for the missed tablet.
Skipping doses or not completing the full course of therapy may
(1) Decrease the effectiveness of the medicine and
(2) Increase the likelihood that bacteria will develop resistance and will not be managable by Tedizolid or other antibacterial drugs in the future.
Overdose
In the event of an overdose, Tedizolid should be discontinued and general supportive treatment should be given.
Side Effects Of STARIZO 200 TABLET
Commonly Experienced Effects
- Headache
- Dizziness
- Nausea, vomiting
- Diarrhea
- Flatulence
- Pruritus generalized
Less Common but Reported Effects
- Fungal and respiratory tract infection
- Dehydration
- Insomnia, sleep disorder, anxiety, nightmare
- Vision blurred
- Bradycardia
- hot flush
- Cough, nasal dryness, congestion
- Arthralgia, muscle spasms, back pain, limb discomfort, neck pain
- Urine odour abnormal
- Chills, irritability, tremor,
- Abdominal pain, constipation, abdominal, discomfort
- Dry mouth, dyspepsia, abdominal
- Pruritus, rash, urticaria
Warning & Precautions
Pregnancy
Monitoring requiredThere are no adequate and well-controlled studies of tedizolid in pregnant women. Tedizolid should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Breastfeeding
Consult your doctorIt is not known whether Tedizolid passes into breast milk. Breastfeeding mothers should consult their doctor before taking the tablet. Temporary interruption of breastfeeding may be advised in some cases.
Driving and Using Machines
Use with CautionSTARIZO 200 may sometimes cause dizziness, tiredness, or visual discomfort in a few individuals. If you experience such symptoms, avoid driving, climbing heights, or using heavy machines until you feel alert.
Alcohol
Consult your doctorAlcohol may worsen dizziness or fatigue in some individuals. If you choose to consume alcohol, do so cautiously and avoid it if you experience discomfort.
Kidney
Consult your doctorSTARIZO 200 is generally handled well in individuals with kidney concerns, but people with severe kidney issues should use the tablet only under medical supervision.
Liver
Consult your doctorIf you have a history of liver concerns, ongoing liver monitoring or dose review may be suggested. Inform your doctor if you have symptoms like fatigue, yellowing of the eyes/skin, or persistent nausea.
Heart Disease
Consult your doctorPeople with pre-existing heart conditions should inform their doctor before using the tablet. Your doctor may check your ongoing therapy or other medicines to ensure compatibility.
Use In Pediatrics
ContraindicatedSTARIZO 200 Tablet is not recommended in children, below 12 years of age.
Use In Geriatrics
Monitoring requiredOlder adults may require additional monitoring because they often take multiple medications. Dose adjustment is usually not necessary, but your doctor may keep an eye on kidney and liver status.
Drug - Drug interaction
1. Medicines that affect serotonin levels
Some medicines used for mood balance or emotional well-being may require monitoring when taken with STARIZO 200. These include:
- Certain antidepressants
- Mood stabilizers
- Medicines for anxiety
Your doctor may adjust the dose or monitor for unwanted reactions.
2. Medicines for migraine
Some migraine-relief medicines can interact and may need spacing or monitoring.
3. Medicines that support immune-related conditions
If you take medicines for autoimmune disorders or inflammation, inform your doctor as they might interact with STARIZO.
4. Blood pressure-related medicines
Certain medicines that regulate blood pressure may require dose review when taken together.
5. Other antibiotics
If you are on multiple anti-infective medicines, your doctor will check compatibility to avoid overlapping effects.
6. Herbal supplements and OTC products
St. John’s Wort, weight-loss supplements, or energy boosters may have interaction potential and should be disclosed to your doctor.
Drug - Food interaction
1. High-fat meals
High-fat meals may slightly change the absorption rate, but this does not impact effectiveness. You may continue your regular diet unless your doctor suggests otherwise.
2. Alcohol
Alcohol may increase dizziness or tiredness in some individuals. It is recommended to consume cautiously and avoid if symptoms appear.
3. Caffeine-containing foods or beverages
Excessive caffeine (coffee, energy drinks, cola) may increase nervousness or restlessness in some individuals when taken along with the tablet.
Synopsis
|
Drug |
: |
Tedizolid |
|
Pharmacological Category |
: |
Oxazolidinone antibiotics |
|
Therapeutic Indication |
: |
Acute bacterial skin and skin-structure infections |
|
Dosage Forms |
: |
Tablet |
More Information
Myth vs Facts
Myth 1: “I must take STARIZO 200 only on an empty stomach.”
Fact: The tablet can be taken with or without food. Your doctor may guide you based on your comfort, routine, or other medicines you take.
Myth 2: “If I feel better after one or two doses, I can stop the medicine.”
Fact: Stopping early may not allow your body to fully clear the infection-causing organisms. Completing the full course, as advised by your doctor, ensures better results.
Myth 3: “Older adults should avoid STARIZO 200.”
Fact: Older adults can use the tablet with proper monitoring. Dose adjustments are usually not required unless advised by a doctor.
Myth 4: “It is unsafe for people with kidney or liver concerns.”
Fact: People with kidney or liver issues can take STARIZO 200, but they may require monitoring. Your doctor will guide you based on your health condition.
Myth 5: “This medicine works instantly after the first dose.”
Fact: While many people start feeling better early, the medicine works gradually by reducing the activity of infection-causing organisms. Consistency is more important than speed.
Points to Remember – STARIZO 200 Tablet
Before You Start Using This Medicine
- Inform your doctor if you have kidney, liver, heart, or lung conditions.
- Share a complete list of all prescription, OTC medicines, supplements, and herbal products you take.
- Mention if you are pregnant, planning pregnancy, or breastfeeding.
- Avoid self-adjusting the dose; always follow doctor’s guidance.
- Check the expiry date and packaging integrity before use.
- Keep the tablet out of reach of children.
While Using This Medicine
- Take the tablet exactly as prescribed, with or without food.
- Swallow the tablet whole with a glass of water; do not crush or chew.
- Maintain consistent timing each day to keep levels steady.
- If you experience dizziness or tiredness, avoid driving or operating heavy machinery.
- Limit alcohol consumption as it may increase side effects like dizziness.
- Report any unusual body reactions, such as persistent nausea, rash, or yellowing of eyes/skin, to your doctor.
- Do not skip doses; if a dose is missed, take it as soon as remembered unless it is almost time for the next dose.
After Using This Medicine
- Complete the full course as prescribed, even if you feel better early.
- Store the remaining tablets in a cool, dry place, away from sunlight and moisture.
- Continue to monitor your overall well-being and report any delayed reactions to your healthcare provider.
- Dispose of any unused or expired tablets safely, following local regulations or pharmacy advice.
- Schedule follow-up appointments if your doctor recommends monitoring kidney, liver, or blood parameters.
The Science Behind How STARIZO 200 Tablet Works
- Tedizolid phosphate, a broad-spectrum oxazolidinone antibiotic offers antibacterial activity against the most important ABSSSIs pathogens including MRSA & some linezolid-resistant S. aureus and cfr-mediated & vancomycin-resistant enterococci.
- Tedizolid has potent activity against gram-positive cocci, offers high oral bioavailability, convenience of once a day dosing, lower risk of drug-drug interactions, better safety profile at 6 days compared to 10 days with linezolid.
- This makes tedizolid an attractive alternative for ABSSSI
Hypersensitivity to Tedizolid 200 mg or to any of the excipients
- Tedizolid phosphate is a prodrug that is rapidly converted by endogenous phosphatases to tedizolid, the microbiologically active moiety.
- 10 Tedizolid, a bacteriostatic antibiotic inhibits bacterial protein synthesis by acting on the initiation step of protein synthesis.
- Tedizolid, binds to the 23S ribosomal RNA of the 50S subunit & inhibits its activity, avoiding its association with the 30S subunit. Thus, the formation of a functional 70S initiation complex that initiates protein synthesis in the bacteria is stopped.
Did you know
- Patients should be advised that antibacterial drugs including Tedizolid should only be used to manage bacterial infections.
- Tedizolid does not manage viral infections (e.g., the common cold). When Tedizolid is prescribed to manage a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed.
FAQs About STARIZO 200 TABLET
Q: What is STARIZO 200 Tablet used for?
A: STARIZO 200 contains Tedizolid and is prescribed for certain types of bacterial infections. It helps the body manage these infections under the guidance of a healthcare professional.
Q: How should I take STARIZO 200 Tablet?
A: Swallow the tablet whole with a glass of water. It can be taken with or without food, usually once daily, as directed by your doctor.
Q: Can I take STARIZO 200 with food or on an empty stomach?
A: Yes. STARIZO 200 can be taken with or without food. Food does not affect its activity or absorption.
Q: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one. Do not double the dose to make up for a missed tablet.
Q: Are there any side effects of STARIZO 200 Tablet?
A: Some people may experience mild side effects such as nausea, headache, or dizziness. Most reactions are temporary. Contact your doctor if you notice any unusual or persistent symptoms.
Q: Can I take STARIZO 200 with other medicines?
A: Inform your doctor about all other medicines, supplements, or herbal products you take. Certain medicines, including antidepressants or migraine medications, may need special monitoring.
Q : Is STARIZO 200 safe during pregnancy or breastfeeding?
A: Limited information is available. Only use STARIZO 200 if clearly advised by your healthcare professional after assessing the benefits and potential risks.
Q: Can I drive or operate machinery while taking STARIZO 200?
A: Some individuals may feel dizziness or fatigue. Avoid driving or using heavy machinery if you experience these effects.
Q: Can I consume alcohol while taking STARIZO 200?
A: Alcohol may increase dizziness or tiredness. It is recommended to limit or avoid alcohol during the course of this medicine.
Q: How should I store STARIZO 200 Tablet?
A: Keep the tablets in a cool, dry place, away from sunlight and moisture. Ensure it is out of reach of children and follow any additional storage instructions on the packaging.
References
1. KD Tripathi. Beta-Lactam Antibiotics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 723.
2.Merck & Co. Sivextro 200 mg film-coated tablets. Electronic Medicines Compendium. [Revised in February 2025]. [Accessed on 6th December 2025]. ![]()
3. Incepta Pharmaceuticals Ltd. Tezolid. [Accessed on 6th December 2025]. 







