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INTRODUCTION
SPASMONORM M TABLET is a combination of Camylofin and Mefenamic acid which belongs to the group of medicines called Antispasmodic and Nonsteroidal anti-inflammatory drugs (NSAIDs) respectively. It is used to treat renal colic (pain when stone gets stuck in the urinary tract causing painful, bloody, or cloudy urination), biliary colic (pain in the abdomen due to obstruction by stones in bile duct), intestinal colic (cramp like pain in the small or large intestine) and dysmenorrhea (period or menstrual cramps around the abdomen, hips, lower back).
Having a fiber rich diet, keeping yourself hydrated, quitting smoking and alcohol will help in the treatment process. Prior to the treatment your doctor might want you to take certain blood tests. Before taking SPASMONORM M TABLET inform your doctor if you have liver, kidney, heart, prostate gland, thyroid gland, lung problems, stomach ulcers, bleeding disorder, diabetes, cholesterol, bowel problems, systemic lupus erythematosus, having a surgery, glaucoma, fever, epilepsy or blood circulation problems.
Avoid consumption of alcohol during treatment with SPASMONORM M TABLET. It is not recommended for use in pregnant and breastfeeding women. SPASMONORM M TABLET is not recommended for use in children and adolescents below 12 years of age. It should be used with caution in elderly patients above 65 years of age. The most common side effects of taking SPASMONORM M TABLET are nausea, vomiting, heartburn, stomach pain and diarrhea. Consult your doctor if any of the above side effects do not improve.
USES OF SPASMONORM M TABLET
It is used to treat:
- renal colic
- biliary colic
- intestinal colic
- period cramps
HOW SPASMONORM M TABLET WORKS
SPASMONORM M TABLET works by relieving muscle cramps and pain in which Camylofin relaxes the muscles in the stomach and intestine stopping sudden muscle contractions (spasms). Mefenamic acid inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of prostaglandins that cause inflammation (redness and swelling) and pain.
DIRECTIONS FOR USE
Take SPASMONORM M TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending upon your age, body weight and disease condition.
SIDE EFFECTS OF SPASMONORM M TABLET
COMMON
- stomach pain
- heartburn
- dry mouth
- nausea, vomiting
- diarrhea
- indigestion
- loss of appetite
- headache
- dizziness
- vertigo
- skin rash
- dry skin or mouth
- raised heart rate
RARE
Stop taking SPASMONORM M TABLET and contact your doctor immediately if you experience any of the following side effects:
- allergic reactions such as skin rash, itching, bruising, painful red areas, peeling or blistering, facial swelling
- serious skin rashes including Stevens-Johnson syndrome and Lyell’s syndrome, swollen face, lips, hands or fingers
- wheezing and feeling of tightness in the chest, uncomfortable breathing, swelling of the face, lips, mouth, tongue or throat, blistering or peeling of the skin or mucous membrane
- diarrhea, passing black tarry stools or vomiting blood
HOW TO MANAGE SIDE EFFECTS
Bloating
Eat smaller and frequent meals, exercise regularly. If the symptom does not show improvement, consult your doctor.
Diarrhea
Drink lots of water or fruit juice to keep yourself hydrated. If the symptom does not show improvement, consult your doctor.
Headache
Avoid bright lights, take enough rest and drink more water. If the symptom does not show improvement, consult your doctor.
Loss Of Appetite
Snack only when you're hungry. Eat a nutritious snack, such as dried fruit and nuts. If the symptom does not show improvement, consult your doctor.
Nausea And Vomiting
Take this medicine with meals. Stick to simple meals. Avoid eating rich or spicy food. If the symptom does not show improvement, consult your doctor.
Stomach Pain
Try to rest and relax. Keep a heat pad. If the symptom does not improve, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
Consult your doctorSPASMONORM M TABLET is not recommended for use in pregnant women (more than 6 months) or women who are planning to become pregnant. SPASMONORM M TABLET should be used with caution in first 6 months of pregnancy. Consult your doctor before taking it.
BREASTFEEDING
ContraindicatedSPASMONORM M TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking SPASMONORM M TABLET.
DRIVING AND USING MACHINES
Use with CautionDo not drive or use machines while taking SPASMONORM M TABLET as it may cause dizziness, drowsiness, fatigue and visual disturbances which may affect their ability to drive or operate machines.
ALCOHOL
Consult your doctorAvoid consumption of alcohol while taking SPASMONORM M TABLET as it can increase the risk of stomach bleeding.
KIDNEY
Consult your doctorSPASMONORM M TABLET is not recommended for use in patients with severe kidney disease. SPASMONORM M TABLET should be used with caution in patients with mild to moderate kidney disease. Consult your doctor before taking.
LIVER
Consult your doctorSPASMONORM M TABLET is not recommended for use in patients with severe liver disease. SPASMONORM M TABLET should be used with caution in patients with mild to moderate liver disease. Consult your doctor before taking.
ALLERGY
ContraindicatedDo not take SPASMONORM M TABLET if you are allergic to Camylofin, Mefenamic acid or any other ingredients of this medicine.
LUNGS
Use with CautionSPASMONORM M TABLET should be used with caution in patients with obstructive airway disease, asthma and other lung disease. Consult your doctor before taking.
HEART DISEASE
Consult your doctorSPASMONORM M TABLET is not recommended for use in patients who had a heart bypass surgery, mechanical stenosis and other serious heart problems. SPASMONORM M TABLET should be used with caution in patients with previous stroke, heart failure, cardiac surgery, high blood pressure. Consult your doctor before taking.
USE IN PEDIATRICS
ContraindicatedSPASMONORM M TABLET is not recommended for use in children and adolescents below 12 years of age. Consult your doctor before taking.
USE IN GERIATRICS
Use with CautionSPASMONORM M TABLET should be used with caution in elderly patients above 65 years of age as they are more prone to side effects. If needed dose will be adjusted accordingly. Consult your doctor before taking SPASMONORM M TABLET.
OTHERS
SPASMONORM M TABLET is not recommended for use if you:
- have glaucoma
- have gastrointestinal disorder like peptic ulcer, bleeding stomach or severe gastritis
- have prostatic hypertrophy
- inflammatory bowel disease (Ex. ulcerative colitis, crohn's disease)
Before taking SPASMONORM M TABLET inform your doctor if you:
- have thyroid gland problem
- have fever
- have diabetes
- have high cholesterol
- have bleeding disorder
- have systemic lupus erythematosus (SLE) or mixed connective tissue disease
- have or had a surgery
- have epilepsy
- are dehydrated
- are intolerant to certain sugars
INTERACTIONS
A. Drug-Drug interactions:
Before taking SPASMONORM M TABLET, inform your doctor if you are taking any of the following medicine:
- anticoagulant (Ex. warfarin, aspirin, clopidogrel, to treat clotting problems)
- corticosteroids used to treat arthritis and inflammation (Ex. prednisone)
- medications used to treat diabetes (Ex. metformin, glipizide)
- antidepressants (Ex. amitriptyline, paroxetine, imipramine, desipramine, lithium)
- diuretics (water pill)
- anticancer agent (Ex. methotrexate)
- medications that suppress the immune system (Ex. tacrolimus, ciclosporin)
- quinolone antibiotics, other pain killers (Ex. aspirin, ibuprofen)
- medication used to terminate the pregnancy (Ex. mifepristone)
- medicine used to treat heart problems (Ex. digoxin), steroids, heart rhythm problems (quinidine) to treat high blood pressure (Ex. lisinopril, captopril, atenolol, ramipril, valsartan)
- medicine used to treat movement disorders (Ex. amantadine)
- aminoglycoside antibiotics (Ex. gentamicin, amikacin)
- zidovudine (used for HIV)
- probenecid (used in the treatment of chronic gout or gouty arthritis)
- medicines which bind to protein in the blood
Overdosage:
If you or anyone else accidentally takes too much of SPASMONORM M TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms include headache, abdominal pain, nausea, vomiting, diarrhea, disorientation, excitation, tiredness, ringing in the ears and fainting.
SYNOPSIS
| Drug | : | Camylofin, Mefenamic acid |
| Pharmacological Category | : | Antispasmodic, Nonsteroidal anti-inflammatory drugs (NSAIDs) |
| Therapeutic Indication | : | Renal colic, Biliary colic, Intestinal colic, Period cramps |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep SPASMONORM M TABLET out of reach of children
- Store at room temperature
FAQs ABOUT SPASMONORM M TABLET
Q: What is SPASMONORM M TABLET used for?
A: SPASMONORM M TABLET is used in the treatment of renal colic (pain when stone gets stuck in the urinary tract causing painful, bloody, or cloudy urination), biliary colic (pain in the abdomen due to obstruction by stones in bile duct), intestinal colic (cramp like pain in the small or large intestine) and dysmenorrhea (period or menstrual cramps around the abdomen, hips, lower back).
Q: Can SPASMONORM M TABLET be used in patients with kidney problems?
A: SPASMONORM M TABLET is not recommended for use in patients with severe kidney disease and should be used with caution in patients with mild to moderate kidney disease. Consult your doctor before taking.
Q: Can SPASMONORM M TABLET be used in pregnant women?
A: SPASMONORM M TABLET is not recommended for use in pregnant women (more than 6 months) or women who are planning to become pregnant and should be used with caution in first 6 months of pregnancy. Consult your doctor before taking.
Q: How does SPASMONORM M TABLET work?
A: SPASMONORM M TABLET works by relieving muscle cramps and pain in which Camylofin relaxes the muscles in the stomach and intestine stopping sudden muscle contractions (spasms). Mefenamic acid inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of prostaglandins that cause inflammation (redness and swelling) and pain.
Q: Can SPASMONORM M TABLET be used in elderly patients?
A: SPASMONORM M TABLET should be used with caution in elderly patients above 65 years of age as they are more prone to the side effects. Dose will be adjusted by the doctor. Consult your doctor before taking.
REFERENCES
1. Goodman. Gilman. Anti-Inflammatory, Antipyretic, and Analgesic Agents, Pharmacotherapy of Gout. The pharmacological basis of therapeutics. Twelfth Edition. 2011. Page – 989.
2. David F. Sigmon; Nalin Dayal; Marcelle Meseeha. Biliary Colic. [Revised on May 2022] [Accessed on 1st July 2022] https://www.ncbi.nlm.nih.gov/books/NBK430772/
3. Bethesda. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. [Revised on January 2020] [Accessed on 1st July 2022] https://www.ncbi.nlm.nih.gov/books/NBK548029/
4. Lelypharma. B.V. Electronic Medicines Compendium (EMC). [Revised in April 2020] [Accessed on 1st July 2022] https://www.medicines.org.uk/emc/files/pil.12890.pdf
5. Dales Pharmaceuticals Ltd. Health Products Regulatory Authority (HPRA). [Revised in June 2015] [Accessed on 1st July 2022] https://www.hpra.ie/img/uploaded/swedocuments/2165303.PA0074_015_001.3ccbf7a3-ae11-40c9-a176-e9219fbd7903.000001Mefac%20PIL.150821.pdf
6. Camylofin. Pubchem. [Accessed on 1st July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Camylofin
7. CIMS. Camylofin. [Accessed on 1st July 2022] https://www.mims.com/india/drug/info/camylofin?type=full&mtype=generic
8. Camylofin + Mefenamic acid. Medicineindia. [Accessed on 1st July 2022] https://www.medicineindia.org/pharmacology-for-generic/3033/camylofin-dihydrochloride-mefenamic-acid
9. Camylofin + Mefenamic acid. Clevelandclinic. [Revised in April 2022] [Accessed on 1st July 2022] https://my.clevelandclinic.org/health/diseases/22847-renal-colic
10. Camylofin + Mefenamic acid. Healthline. [Revised on March 2018] [Accessed on 1st July 2022] https://www.healthline.com/health/colicky-pain
11. Camylofin + Mefenamic acid. Clevelandclinic. [Revised in November 2020] [Accessed on 1st July 2022] https://my.clevelandclinic.org/health/diseases/4148-dysmenorrhea
USEFUL DIAGNOSTIC TESTS
- Blood tests
AUTHOR DETAILS
Written By Dr. Janet.C, Pharm.D
Last updated on 01 Mar 2023 | 09:53 AM(IST)
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