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Introduction About SKELACT TABLET
SKELACT TABLET contains Eperisone, which belongs to the group of medicines called Muscle Relaxants. It is used to manage and improve the myotonic condition of the muscles caused by neck-shoulder arm syndrome (a condition causing muscle pain and stiffness in the neck, arm, and shoulder region), scapulohumeral periarthritis (a condition causing muscle pain and stiffness in the shoulder joint), and low back pain (a painful condition affecting the lower region of the spine due to a muscle or ligament injury).
The myotonic condition causes wasting and weakness of the muscle when its functional ability to relax is impaired. It is also used to manage spastic paralysis (loss of muscle function along with pain and muscle stiffness) caused by a spinal or neurological disorder, trauma, cerebral palsy, tumour in the spine, etc.
SKELACT TABLET should be used with caution in patients with liver function disorders. SKELACT TABLET is generally not recommended for use during pregnancy unless recommended by your doctor. SKELACT TABLET is not recommended for use by breastfeeding women. Its safety and efficiency for use in children have not been established. Consult your doctor for advice before taking SKELACT TABLET.
The most common side effects of taking SKELACT TABLET may include weakness, light-headedness, fatigue, sleepiness, insomnia, headache, nausea, vomiting, loss of appetite, abdominal pain, diarrhea, constipation, and thirst. Consult your doctor if any of the above side effects worsen or persist.
Uses Of SKELACT TABLET
- Manage and improves the myotonic condition (wasting and weakness) of the muscle
- Manage spastic muscle paralysis
How SKELACT TABLET Works
SKELACT TABLET works by blocking the voltage-gated sodium channel in the brain stem. As a result, it stops nerve signals and aids in the relaxation of muscles.
How to use SKELACT TABLET
Take SKELACT TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose, frequency, and duration of management for you depending upon your age, body weight, and disease condition.
Side Effects Of SKELACT TABLET
Common
- weakness, light-headedness, fatigue
- sleepiness, insomnia, headache
- nausea, vomiting, loss of appetite, abdominal pain, diarrhea, constipation, and thirst
Rare
Stop taking SKELACT TABLET and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reaction
Warning & Precautions
Pregnancy
SKELACT TABLET is generally not recommended for use during pregnancy unless recommended by your doctor. Contact your doctor before taking SKELACT TABLET.
Breastfeeding
SKELACT TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking SKELACT TABLET.
Driving and Using Machines
Do not drive or operate any machines if you feel weakness, sleepiness, or light-headedness after taking SKELACT TABLET.
Liver
SKELACT TABLET should be used with caution in patients with a disorder of liver function. Consult your doctor before taking SKELACT TABLET.
Allergy
SKELACT TABLET is not recommended for use if you are allergic to Eperisone.
Others
Use in pediatrics:
As its safety and effectiveness in children is not established yet, consult your doctor about the risk and benefits before taking SKELACT TABLET.
Use in geriatrics:
SKELACT TABLET should be used with caution in elderly patients. Contact your doctor before taking SKELACT TABLET.
Interactions
A. Drug-Drug interactions:
- methocarbamol (a medicine used to manage muscle spasms or stiffness)
Overdosage:
If you or anyone else have accidentally taken too much of SKELACT TABLET, consult your doctor immediately or visit the nearby hospital as overdosage can result in abnormal heart function.
Synopsis
| Drug | : |
Eperisone |
| Pharmacological Category | : |
Muscle Relaxant |
| Therapeutic Indication | : |
Muscle spasm or pain |
| Dosage Forms | : |
Tablet, Capsule |
More Information
- keep SKELACT TABLET out of reach from children
- store at room temperature
FAQs About SKELACT TABLET
Can SKELACT TABLET be used to manage muscle pain?
Yes, SKELACT TABLET relieves muscle pain and relaxes the muscle by blocking the voltage-gated sodium channel in the brain stem, thereby stopping the conduction of nerve signals.
Can SKELACT TABLET be used in pregnant and nursing mothers?
SKELACT TABLET is generally not recommended for use during pregnancy unless considered necessary by your doctor. SKELACT TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking it.
Can SKELACT TABLET cause dizziness?
Yes, SKELACT TABLET may cause dizziness. If you start to feel dizzy, sit down immediately or lay down in a quiet and dark area with your eyes closed. Consult your doctor if the symptom worsens or persists.
Can SKELACT TABLET be taken by patients with liver disease?
SKELACT TABLET should be used with caution in patients having a liver function disorder, as this medicine may aggravate the existing condition. Consult your doctor for advice.
How does SKELACT TABLET work?
SKELACT TABLET works by blocking the voltage-gated sodium channel in the brain stem. As a result, it stops nerve signals and aids in the relaxation of muscles.
References
1. Kamran Ahmed, Muhammad Harris Shoaib, Rabia Ismail Yousuf, Fahad Siddiqui, Faaiza Qazi, Javeria Iftikhar, Farrukh Rafiq Ahmed, and Muhammad Iqbal Nasiri. Comparative pharmacokinetics of osmotic-controlled and immediate-release Eperisone tablet formulation in healthy human subjects using a sensitive plasma LC-ESI-MS/MS method. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. October 2020. [Accessed 7th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002734/
2. Takeshi Yamagiwa, Seiji Morita, Mari Amino, Naoya Miura, Takeshi Saito, Sadaki Inokuchi. Serum concentration of eperisone hydrochloride correlates with QT interval. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. January 2014. [Accessed 7th June 2022] https://pubmed.ncbi.nlm.nih.gov/24135462/
3. Rizaldy Taslim Pinzon, Vincent Ongko Wijaya, Dessy Paramitha, and Raymondus Ranga Bagaskara. Effects of Eperisone Hydrochloride and Non-Steroid Anti-Inflammatory Drugs for Acute Non-Specific Back Pain with Muscle Spasm: A Prospective, Open-Label Study. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. November 2020. [Accessed 7th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678690/
4. Eisai Co., Ltd. [Revised in July 2009] [Accessed 7th June 2022] http://www.shijiebiaopin.net/upload/product/201082521391314.pdf
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