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*10 Tablet(s) in a Strip * Mkt: Dales Laboratories Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout


INTRODUCTION

SINUS 77 ADVANCED TABLET is a combination of Caffeine, Diphenhydramine, Paracetamol, and Phenylephrine which belongs to the group of medicines called CNS Stimulants, Antihistamines, Analgesics-Antipyretics, and Nasal Decongestants respectively. It is used to relieve flu and cold symptoms, headache, body ache, extreme weakness, watery eyes, fever, cough, sore throat, sneezing, runny, and congested nose.

SINUS 77 ADVANCED TABLET is not recommended for use in children and adolescents (aged less than 12 years). Before taking SINUS 77 ADVANCED TABLET, inform your doctor if you have any heart, kidney, liver, heart, thyroid, prostrate, or breathing problems, or if you are taking any medicines for depression.

SINUS 77 ADVANCED TABLET is not recommended for use in pregnancy. SINUS 77 ADVANCED TABLET should be used with caution in breastfeeding women, so consult your doctor before taking it. The most common side effects of taking SINUS 77 ADVANCED TABLET are nausea, vomiting, headache, sleep problems, sleepiness, restlessness, dizziness. Contact your doctor if any of the above side effects worsen.

USES OF SINUS 77 ADVANCED TABLET

It is used to relieve:

  • flu and cold symptoms
  • headache
  • body ache
  • extreme weakness
  • watery eyes
  • fever
  • cough
  • sore throat
  • sneezing, runny and congested nose

HOW SINUS 77 ADVANCED TABLET WORKS

SINUS 77 ADVANCED TABLET relieves cold and flu symptoms where paracetamol inhibits the release of certain chemical messengers responsible for causing pain and fever, diphenhydramine relieves allergy symptoms like watery eyes, sneezing, and runny nose, phenylephrine narrows the small blood vessels and relieves congestion and stuffy nose, and caffeine enhances the action of paracetamol and decreases drowsiness caused by diphenhydramine.

DIRECTIONS FOR USE

Take SINUS 77 ADVANCED TABLET as advised by your physician. Swallow with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of SINUS 77 ADVANCED TABLET for you according to your age, body weight and disease condition.

SIDE EFFECTS OF SINUS 77 ADVANCED TABLET

COMMON

  • nausea, vomiting
  • headache, dizziness
  • sleep problems, sleepiness
  • restlessness

Stop taking SINUS 77 ADVANCED TABLET and contact your doctor immediately if you experience any of the following side effects:

  • tiredness, drowsiness, reduced attention, unsteadiness, dry mouth
  • allergic reactions (rash, breathlessness, swelling)
  • blurred vision
  • throbbing sensation, irregular heartbeat
  • muscle twitching, fits, pins and needles sensation
  • thicker bronchial mucus
  • trouble passing urine
  • serious skin reactions like acute generalized exanthematous pustulosis (AGEP), Steven Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN)

HOW TO MANAGE SIDE EFFECTS

Dizziness Or Drowsiness

Lie down until dizziness is resolved, then get up slowly. Do not hurry and move slowly and carefully. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol, and drugs. If dizziness does not improve, consult your doctor.

Headache

Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Consult your doctor before taking any medicine for headache. If headache does not improve, contact your doctor.

Nausea And Vomiting

Take SINUS 77 ADVANCED TABLET with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If nausea does not improve, contact your doctor. Get adequate rest. Drink lots of fluids, especially water. Have small sips if you feel sick. Do not take any medicine for vomiting without your doctor's consultation. If vomiting does not improve, contact your doctor.

WARNING & PRECAUTIONS

PREGNANCY
Contraindicated

SINUS 77 ADVANCED TABLET is not recommended for use in pregnant women. Consult your doctor before taking it.

BREASTFEEDING
Use with Caution

SINUS 77 ADVANCED TABLET should be used with caution in breastfeeding women. Consult your doctor before taking it.

DRIVING AND USING MACHINES
Use with Caution

Do not drive or use any machines if you feel dizzy or sleepy or have decreased alertness after taking SINUS 77 ADVANCED TABLET.

ALCOHOL
Consult your doctor

Avoid consumption of alcohol with SINUS 77 ADVANCED TABLET. It should be used with caution in chronic alcohol users and patients with alcohol dependence. Consult your doctor for advice.

KIDNEY
Use with Caution

SINUS 77 ADVANCED TABLET should be used with caution in patients having kidney problems and urinary retention. Consult your doctor before taking it.

LIVER
Use with Caution

SINUS 77 ADVANCED TABLET should be used with caution in patients with alcoholic liver disease or other liver problems. Consult your doctor before taking it.

ALLERGY
Contraindicated

Do not take SINUS 77 ADVANCED TABLET if you are allergic to Caffeine, Diphenhydramine, Paracetamol, Phenylephrine, or any of the other ingredients of this medicine.

LUNGS
Use with Caution

SINUS 77 ADVANCED TABLET should be used with caution in patients with respiratory conditions like emphysema, chronic bronchitis, or bronchial asthma. Consult your doctor before taking it.

HEART DISEASE
Consult your doctor

SINUS 77 ADVANCED TABLET is not recommended in patients with serious heart conditions or high blood pressure. SINUS 77 ADVANCED TABLET should be used with caution in patients with Raynaud’s phenomenon (a blood vessel disease), and other heart or circulation diseases. Consult your doctor before taking it.

USE IN PEDIATRICS
Contraindicated

SINUS 77 ADVANCED TABLET is not recommended for use in children and adolescents (aged less than 12 years). Consult your doctor before taking it.

USE IN GERIATRICS
Use with Caution

SINUS 77 ADVANCED TABLET should be used with caution in elderly patients. Consult your doctor before taking it.

OTHERS

SINUS 77 ADVANCED TABLET is not recommended for use if you:

  • have an overactive thyroid
  • have an enlarged prostate gland or other prostrate problems
  • have persistent or chronic cough, or cough with excessive secretions

Before taking SINUS 77 ADVANCED TABLET, inform your doctor if you:

  • have increased pressure inside your eye
  • have diabetes (high blood sugar)

INTERACTIONS

A. Drug-Drug interactions:

Before taking SINUS 77 ADVANCED TABLET, inform your doctor if you are taking any of the following medicine:

  • cholestyramine (used to reduce blood fat levels)
  • medicines used to treat nausea (Ex. metoclopramide, domperidone)
  • medicines use for blood thinning (Ex. warfarin, psoralen)
  • medicines used to treat high blood pressure and other heart or circulatory problems (Ex. atenolol, methyldopa, trimetaphancamsylate)
  • medicines used to treat depression (Ex. amitriptyline, phenelzine)
  • atropine (used for pupil dilation)
  • medicines used to treat allergies of skin and in cold and cough (Ex. chlorpheniramine, clemastine)
  • flucloxacillin (used to treat infections)

B. Drug-Food interaction:

Avoid caffeine-containing medications, food, and beverages like tea and coffee while taking SINUS 77 ADVANCED TABLET as it may cause shaking, uncomfortable feeling in the chest or difficulty sleeping.

Overdosage:

If you or anyone else accidentally took too much of SINUS 77 ADVANCED TABLET, contact your doctor immediately. Symptoms of overdose are liver damage.

SYNOPSIS

Drug :   Caffeine, Diphenhydramine, Paracetamol, Phenylephrine
Pharmacological Category :   CNS stimulant, Direct sympathomimetic, Antipyretic-analgesic, Nasal Decongestants
Therapeutic Indication :   Symptoms of cold and flu
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep SINUS 77 ADVANCED TABLET out of reach of children
  • Store below 25°C

FAQs ABOUT SINUS 77 ADVANCED TABLET

Q: What are the uses of SINUS 77 ADVANCED TABLET?

A: SINUS 77 ADVANCED TABLET contains Caffeine, Diphenhydramine, Paracetamol, and Phenylephrine which altogether provides relief from flu and cold symptoms, headache, body ache, extreme weakness, watery eyes, fever, cough, sore throat, sneezing, runny, and congested nose.

Q: Can SINUS 77 ADVANCED TABLET be crushed?

A: No. Do not break, crush or chew SINUS 77 ADVANCED TABLET. Simply swallow it whole with a glass of water. Consult your doctor for advice.

Q: Can SINUS 77 ADVANCED TABLET cause drowsiness?

A: Yes. SINUS 77 ADVANCED TABLET may cause drowsiness or sleepiness. Therefore, avoid operating machinery or driving vehicles, and other activities requiring mental concentration. Avoid caffeine-containing medications, food, and beverages like tea and coffee to prevent drowsiness while taking SINUS 77 ADVANCED TABLET as it already contains caffeine and too much caffeine may cause shaking, uncomfortable feeling in the chest or difficulty sleeping.

Q: Can SINUS 77 ADVANCED TABLET be given to children?

A: No. SINUS 77 ADVANCED TABLET is not recommended for children and adolescents below 12 years of age. Your doctor will decide the correct dose or select a suitable alternative treatment for your child.

Q: Will steam inhalation make SINUS 77 ADVANCED TABLET more effective?

A: You can also try steam inhalation while taking SINUS 77 ADVANCED TABLET, which may be helpful to relieve the symptoms quickly. However, consult your doctor for advice.

Q: What if I forget to take a dose of SINUS 77 ADVANCED TABLET?

A: If you forget to take a dose of SINUS 77 ADVANCED TABLET, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take the medicine twice to make up for the missed dose.

Q: Can SINUS 77 ADVANCED TABLET be stopped?

A: Continue taking SINUS 77 ADVANCED TABLET until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. In such case, contact your doctor right away.

Q: Does SINUS 77 ADVANCED TABLET cause nausea?

A: Yes. Nausea is a common side effect of SINUS 77 ADVANCED TABLET. If you feel nauseous, take SINUS 77 ADVANCED TABLET with, or just after meals. Stick to simple meals and avoid eating oily or spicy foods. If nausea does not improve, contact your doctor.

Q: What precautions do I need to follow while taking SINUS 77 ADVANCED TABLET?

A: Patients taking SINUS 77 ADVANCED TABLET must inform their doctor about their pre-existing conditions like heart, kidney, liver, heart, thyroid, breathing, or prostrate problems, or if you are taking any medicines for depression. Patients should also inform if they are pregnant, breast-feeding, or having any allergies. Consult your doctor if you experience anything different.

Q: Can SINUS 77 ADVANCED TABLET be taken during pregnancy?

A: SINUS 77 ADVANCED TABLET is not recommended for use in pregnancy. If you are pregnant, think you may be pregnant or are planning to get pregnant, consult your doctor before taking it. Inform your doctor immediately if you become pregnant during treatment with SINUS 77 ADVANCED TABLET.

REFERENCES

1. KD. Tripathi. CNS Stimulants and Cognition Enhancers. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 488.

2. Picon, Paulo Dornelles, Marisa Boff Costa, Rafael da Veiga Picon, Lucia Costa Cabral Fendt, Maurício Leichter Suksteris, Indara Carmanim Saccilotto, Alicia Dorneles Dornelles, and Luis Felipe Carissimi Schmidt. Symptomatic treatment of the common cold with a fixed-dose combination of paracetamol, chlorphenamine and phenylephrine: a randomized, placebo-controlled trial. BMC infectious diseases. November 2013. [Accessed on 15th July 2022] https://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-13-556

3. Unique Pharmaceutical Laboratories. Caffeine + Diphenhydramine + Paracetamol + Phenylephrine. [Accessed on 15th July 2022] https://www.coldarin.in/productdetails

4. Medlock Healthcare. Caffeine + Diphenhydramine + Paracetamol + Phenylephrine. [Accessed on 15th July 2022] https://www.medlockhealthcare.in/product/paracetamol-325-mg-phenylephrine-5-mg-ambroxol-60-mg-levocetirizine-2-5-mg

5. Alpha Drugs. Caffeine + Diphenhydramine + Paracetamol + Phenylephrine. [Accessed on 15th July 2022] https://www.alphadrug.in/product/conzynil-plus-tab

AUTHOR DETAILS

Written By Dr. Dhivakaran R, BDS
Last updated on 22 Mar 2023 | 05:53 PM(IST)

PRODUCT DETAILS
    Net Qty
    1 N
    Shelf Life
    720
    Item Weight
    17.5 g
    Ingredient
    Caffeine 30 mg+Diphenhydramine 25 mg+Paracetamol 500 mg+Phenylephrine 5 mg
    Hsn Code
    30049031
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