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Drug Information

What is Chlorpheniramine + Pseudoephedrine combination used for?

Chlorpheniramine + Pseudoephedrine combination oral drops/ syrup is used for the treatment of following conditions:

  • Common cold
  • Flu
  • Allergies
  • Sinusitis
  • Bronchitis

Chlorpheniramine + Pseudoephedrine combination may also be prescribed for other conditions as determined by the doctor.

How does Chlorpheniramine + Pseudoephedrine combination work?

In Chlorpheniramine + Pseudoephedrine combination, Chlorpheniramine belongs to the class of drugs called anti-histamine and anti-allergic agents. The drug acts by reducing the effect of a chemical (histamine) that is responsible for causing allergic symptoms. Thus, it helps in reducing allergic reactions.

Pseudoephedrine belongs to the class of drugs called nasal decongestants. The drug acts by shrinking the blood vessels in the nasal cavity as dilated blood vessel may cause nasal congestion, thereby treating common cold.

How to take Chlorpheniramine + Pseudoephedrine combination?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Chlorpheniramine + Pseudoephedrine combination oral drops/ syrup as prescribed by your doctor.

  • Shake the oral drops/syrup well before taking each dose so as to ensure the uniform mixing of the drug. Use a measuring cup while taking each dose.

If you miss a dose of Chlorpheniramine + Pseudoephedrine combination, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

What are the drugs that interact with Chlorpheniramine + Pseudoephedrine combination?

Drugs that interact with Chlorpheniramine + Pseudoephedrine combination are:

  • Dihydroergotamine
  • Ergotamine
  • Furazolidone
  • Isocarboxazid
  • Linezolid
  • Selegiline
  • Sodium Oxybate
  • Topiramate
  • Tranylcypromine
  • Zonisamide

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Chlorpheniramine + Pseudoephedrine combination?

The following are the most common side effects of Chlorpheniramine + Pseudoephedrine combination:

  • Drowsiness
  • Dizziness
  • Trouble sleeping
  • Dry mouth, nose and throat
  • Upset stomach
  • Headache

The following are the severe side effects, and you may require immediate medical attention:

  • Seizure
  • Blurred vision
  • Mood changes
  • Ringing in the ears
  • Difficulty urinating
  • Irregular heartbeat

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Chlorpheniramine + Pseudoephedrine combination?

  • Do not drive or operate heavy machinery if Chlorpheniramine + Pseudoephedrine combination causes dizziness.
  • Avoid consumption of alcohol as it may alter the absorption of Chlorpheniramine + Pseudoephedrine
  • Keep the medication out of reach of children.

You are advised not to take Chlorpheniramine + Pseudoephedrine combination if

  • It has passed the expiry date of the medicine printed on the pack.
  • The foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Chlorpheniramine + Pseudoephedrine combination?

  • Inform your doctor if you have any pre-existing medical conditions, such as

asthma, emphysema, diabetes, glaucoma, heart problems, high blood pressure, kidney problems, liver disease, seizures, stomach problems, hyperthyroidism or enlarged prostate.

  • Tell your doctor if you become pregnant while taking Chlorpheniramine + Pseudoephedrine combinatio
  • Inform the doctor if you have any history of allergic reaction with the usage of Chlorpheniramine + Pseudoephedrine combination.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplement

Frequently asked questions about Chlorpheniramine + Pseudoephedrine combination

  1. How should Chlorpheniramine + Pseudoephedrine combination be stored?
  2. Chlorpheniramine + Pseudoephedrine combination should be stored at a temperature below 25°C away from heat and moisture.

  3. Is it normal to experience constipation while on Chlorpheniramine + Pseudoephedrine combination?
  4. Yes, constipation is one of the side effects of Chlorpheniramine + Pseudoephedrine combination. However, please consult your physician.

  5. Is it safe to alter the dose of Chlorpheniramine + Pseudoephedrine combination?
  6. It is not advisable to alter the dose prescribed. Consult your doctor for dose-related queries.

  7. Can I recommend Chlorpheniramine + Pseudoephedrine combination to others?
  8. It is not advisable to recommend drugs to others as the severity of the condition and medical history is not same for every individual.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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