REDAPT CT Tablet 10's

Kidney Disease/Stones Rx required

Best Price* ₹ 120.00 MRP ₹ 150.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Rene Pharmaceuticals Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

REDAPT CT contains Ferric citrate which belongs to the group of medicines called phosphate binder. It is used for controlling hyperphosphatemia in adult patients with chronic kidney disease who are on dialysis. Hyperphosphatemia is an electrolyte disorder characterized by elevated serum phosphate levels (> 4.5 mg/dl) leading to muscle cramps, bone and joint pain, skin rashes and numbness around the mouth. It is caused mainly due to kidney disease, hormonal imbalance and metabolic disorders. It is highly contraindicated in patients with iron overload syndromes, GI disorders and low blood phosphate levels. Contact your doctor before taking. It is not recommended for use in pregnant and breastfeeding women and in children (under 18 years). Consult your doctor for advice.

REDAPT CT can also be used in the treatment of iron deficiency anemia in adults with chronic kidney disease who are not on dialysis. Iron deficiency anemia is a condition in which the body lacks enough amount of mineral ion “iron” which carries adequate healthy red blood cells in the body. Ferric citrate acts by inhibiting the absorption of phosphate ions in the GI tract and enhancing the elimination of precipitated ferric phosphate in the feces. It also supplements the iron required for the body by enhancing the synthesis of hemoglobin, leading to correction of iron-deficiency anemia.

REDAPT CT must be taken with meals. Along with the treatment, patients are requested to eat their prescribed low phosphate diets to achieve better results. Concomitant use of this medicine with iron therapy (oral or IV) should be strictly avoided, as it may lead to unwanted side effects. The most common side effects of taking this medicine are dark stools, constipation, nausea, vomiting or stomach pain. These are common while taking iron supplements and are nothing to worry about. Contact your doctor if these symptoms bother you.

USES OF REDAPT CT

  • Treats hyperphosphatemia in adult patients with chronic kidney disease who are on dialysis
  • Treat iron-deficiency anemia in adult patients with chronic kidney disease who are not on dialysis

HOW REDAPT CT WORKS

Orally administered ferric citrate, binds to dietary phosphate ions in the gastrointestinal tract and precipitates as ferric phosphate. This compound is highly water insoluble in nature and so it is excreted in the stool, thereby reducing the amount of phosphate absorbed from the GI tract. By doing this, ferric citrate effectively reduces elevated serum phosphate levels and its associated symptoms.

Ferric citrate also supplements the required mineral ion ‘iron’ to the body by enhancing the synthesis of hemoglobin. After transported through enterocytes into the blood, the oxidized ferric ion binds to a plasma protein called transferrin, which helps in the incorporation of hemoglobin.

DIRECTIONS FOR USE

Take REDAPT CT as directed by your physician. It must be taken with meals. Swallow the medicine as whole with a sip of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and health condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF REDAPT CT

SERIOUS

  • vomiting of blood
  • blood in the stools

COMMON

  • dark stools or constipation
  • diarrhea, stomach pain, bloating
  • nausea or vomiting
  • hypophosphatemia (decreased serum phosphorus levels)

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.

Bloating or wind:

Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If the symptoms get worse, contact your doctor immediately.

Constipation: 

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

Dark or black stools:

This is common while taking iron supplements and is nothing to worry about. Talk to a doctor if your poo is black and sticky looking, has red streaks in it, or if you also feel unwell in any other way.

WARNING & PRECAUTIONS

PREGNANCY

REDAPT CT is not recommended for use in pregnant women. Consult your doctor for advice.

BREASTFEEDING

REDAPT CT is not recommended for use in breastfeeding women. Consult your doctor for advice.

ALCOHOL

Avoid consumption of alcohol while taking this medicine.

KIDNEY

REDAPT CT should be taken with caution in patients with kidney disease who are currently not on dialysis. Suitable dose titrations are required in such patients.

LIVER

REDAPT CT should be taken with caution in patients with liver disease. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to ferric citrate.

INTERACTIONS

Talk to your doctor, if you are taking,

  • other medicines containing iron given either orally or as IV (e.g. ferrous ascorbate, ferrous sulphate)
  • medicines used to treat bacterial infection such as fluoroquinolones (e.g. ciprofloxacin, levofloxacin) or tetracyclines (e.g. tetracycline, doxycycline)
  • medicines containing aluminium such as antacids (e.g. aluminium hydroxide)
  • proton pump inhibitors (used to reduce stomach acid production e.g. omeprazole, lansoprazole
  • sertraline (used to treat depression)
  • valproic acid (used to treat epilepsy and mental disorders)
  • vitamin D supplements
  • warfarin (used for blood thinning)
  • acetylsalicylic acid (used to treat pain)
  • methotrexate (used to treat rheumatoid arthritis, cancer and or psoriasis)
  • alendronate (used to treat bone disorders)
  • levodopa (used to treat Parkinson’s disease)
  • levothyroxine (used to treat deficiency of thyroid hormone)

SYNOPSIS

Drug :   Ferric citrate
Pharmacological Category :   Phosphate binder, Iron preparations
Therapeutic Indication :   Hyperphosphatemia
Dosage Forms :   Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT REDAPT CT

Can I chew REDAPT CT?

No. Swallow the medicine as whole with a sip of water. Do not crush or chew the medicine.

Can REDAPT CT cause constipation?

Yes. It can cause constipation in many individuals. This is common while taking iron supplements and is nothing to worry about. Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Can REDAPT CT be taken by children?

No. It is strictly not recommended for use in children and adolescents under 18 years of age. Consult your doctor before taking.

Who should avoid taking REDAPT CT?

It is highly contraindicated for use in patients with iron overload syndromes (such as hemochromatosis), hypophosphatemia (low serum phosphate levels) or active severe gastrointestinal disorders (such as GI bleeding or inflammatory bowel disease). Discuss the risks with your doctor before taking. Suitable dose titrations are also required for patients with kidney disease who are currently not on dialysis.

REFERENCES

1. KD. Tripathi. Haematinics and Erythropoietin. Essentials of medical pharmacology. Seventh edition. 2013. Page – 605.

2. Kenneth Kaushansky and Thomas J. Kipps. Hematopoietic Agents: Growth factor, Minerals and Vitamins. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1082-1083.

3. Daniel D. Bikle. Agents That Affect Bone Mineral Homeostasis. Basic and Clinical Pharmacology. 14th Edition. New York McGarw Hill Education 2018.  Page – 784.

4. Keryx Biopharmaceuticals. A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients with End-Stage Renal Disease on Dialysis. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on December 2014] [Accessed 21st December 2020] https://clinicaltrials.gov/ct2/show/NCT01191255

5. Keryx Biopharmaceuticals. Ferric Citrate in Managing Serum Phosphorus and Iron Deficiency in Anemic Chronic Kidney Disease (CKD) Subjects Not on Dialysis. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on October 2017] [Accessed 21st December 2020] https://clinicaltrials.gov/ct2/show/NCT01736397

6. Akram M. Askar. Hyperphosphatemia, The hidden killer in chronic kidney disease. NCBI; PMC US National Library of Medicine, National Institute of Health. 2015. [Accessed 21st December 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362181/

7. Adam Pennoyer and Mary Barna Bridgeman. Ferric Citrate (Auryxia) for the Treatment of Hyperphosphatemia. NCBI; PMC US National Library of Medicine, National Institute of Health. May 2015. [Accessed 21st December 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422633/

8. Keryx Biopharmaceuticals, Inc. U.S. Food & Drug Administration. [Revised on September 2014] [Accessed 21st December 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/205874s000lbl.pdf

9. Akebia Europe Limited. European Medical Agency (EMA). [Accessed 21st December 2020] https://www.ema.europa.eu/en/documents/product-information/fexeric-epar-product-information_en.pdf

10. Keryx Biopharmaceuticals, Inc. U.S. Food & Drug Administration. [Revised on December 2019] [Accessed 21st December 2020] https://www.auryxia.com/wp-content/uploads/Auryxia_PI_Keryx.pdf

USEFUL DIAGNOSTIC TESTS

  • Serum phosphate levels
  • Serum ferritin levels
  • Serum transferrin levels
  • Kidney function test

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    FERRIC CITRATE 1 GM
    Hsn Code
    30049099
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

REDAPT CT Tablet 10's

REDAPT CT Tablet 10's Mkt: Rene Pharmaceuticals Pvt Ltd

M.R.P.: Rs.150.00
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