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HomeMedicineUlcer/Reflux/Flatule...RABILITE LS Capsule ...
RABILITE LS Capsule 10's - Ulcer/Reflux/Flatulence-Aaa
  • RABILITE LS Capsule 10's - Ulcer/Reflux/Flatulence-Aaa
  • RABILITE LS Capsule 10's - Ulcer/Reflux/Flatulence-Aaa
  • RABILITE LS Capsule 10's - Ulcer/Reflux/Flatulence-Aaa
  • RABILITE LS Capsule 10's - Ulcer/Reflux/Flatulence-Aaa
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RABILITE LS Capsule 10's - Ulcer/Reflux/Flatulence-Aaa
RABILITE LS Capsule 10's - Ulcer/Reflux/Flatulence-Aaa
RABILITE LS Capsule 10's - Ulcer/Reflux/Flatulence-Aaa
RABILITE LS Capsule 10's - Ulcer/Reflux/Flatulence-Aaa
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Torque Pharmaceuticals Pvt Ltd

RABILITE LS Capsule 10's

Ulcer/Reflux/Flatule...
MRP ₹148.50 (Inclusive of all taxes)
New Reduced MRP as per revised GST benefit.
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    Uses|How it works|Directions for use|Side effects|Warning & precautions|Interactions|Synopsis|Useful diagnostic tests

    Introduction About RABILITE LS CAPSULE

    RABILITE LS CAPSULE is indicated for the management of gastroesophageal reflux disease (heartburn, chest pain, nausea, sensation of a lump in the throat, and stomach discomfort). It can also be used to manage peptic ulcers, Zollinger-Ellison syndrome, functional dyspepsia, and diabetic gastroparesis.

    RABILITE LS CAPSULE is a combination of Levosulpiride and Rabeprazole, which belong to the group of medicines called Dopamine D2 antagonists and Proton-pump inhibitors, respectively. Rabeprazole acts by inhibiting the secretions of stomach acid by blocking the proton pump (H+ K+ ATPase) at the secretory surface of gastric parietal cells, and levosulpiride acts by blocking the dopamine D2 receptors in the CTZ (the area in the medulla oblongata that causes vomiting when stimulated) and in the gut, thus facilitating the movement of food from the stomach into the intestines, followed by the healing of ulcers or inflammatory lesions in the stomach and in the esophagus.

    Take RABILITE LS CAPSULE, preferably on an empty stomach. Avoid consumption of alcohol while taking RABILITE LS CAPSULE, as it could potentiate the CNS depressive side effects.

    Patients receiving long-term management (>1 year) with RABILITE LS CAPSULE should be kept on regular surveillance because it can increase the risk of bone fracture (i.e., in the hip, wrist, or spine), which is more prevalent in patients with osteoporosis or taking corticosteroids.

    Before taking RABILITE LS CAPSULE, inform your doctor if you have any heart, kidney, or liver disease as a precaution. RABILITE LS CAPSULE is not recommended for use in pregnant or breastfeeding women, including children and adolescents (aged below 18 years).

    The most common side effects of taking RABILITE LS CAPSULE are nausea, vomiting, stomach pain, diarrhea, constipation, and headaches. Consult your doctor if any of these symptoms worsen.

    Uses Of RABILITE LS CAPSULE

    • Manage Gastro-Oesophageal Reflux Disease (GERD)
    • Manage function dyspepsia
    • Manage peptic ulcers
    • Manage Zollinger-Ellison syndrome
    • Manage diabetic gastroparesis

    How RABILITE LS CAPSULE Works

    RABILITE LS CAPSULE reduces stomach ulcers, nausea, and acid reflux. Rabeprazole acts by inhibiting the secretions of stomach acid by blocking the proton pump (H+ K+ ATPase) at the secretory surface of gastric parietal cells, while levosulpiride acts by blocking the dopamine D2 receptors in the CTZ (area in the medulla oblongata that causes vomiting when stimulated) and in the gut, thus facilitating the movement of food from the stomach into the intestines, followed by the healing of ulcers or inflammatory lesions in the stomach and in the esophagus.

    How to use RABILITE LS CAPSULE

    Take RABILITE LS CAPSULE on an empty stomach or as advised by your physician. Swallow RABILITE LS CAPSULE as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.

    Side Effects Of RABILITE LS CAPSULE

    Common

     

    • Infections, weakness, or flu-like symptoms
    • Difficulty sleeping
    • Headache or dizziness
    • Cough, runny nose, or sore throat
    • Nausea, vomiting, stomach pain, diarrhea, wind (flatulence), or constipation
    • Aches or back pain
    • Benign polyps in the stomach

    Uncommon

     

    • Nervousness, drowsiness
    • Chest infection
    • Sinusitis (painful and blocked sinuses)
    • Dryness of the mouth
    • Indigestion or belching
    • Skin rash or redness
    • Leg pain, muscle pain, or joint pain
    • Fractures of the spine, hip, and wrist
    • Urinary tract infection
    • Chest pain
    • Fever or chills

    Rare

     

    • Loss of appetite
    • Depression
    • Visual disturbance
    • Sore mouth, taste disturbance
    • Stomach upset or pain
    • Sweating
    • Kidney problems
    • Weight gain

    Stop taking RABILITE LS CAPSULE and contact your doctor immediately if you experience any of the following side effects:

    • Skin rash on sun-exposed areas with joint pain
    • Severe (watery or bloody) diarrhea accompanied by fever, abdominal pain, or tenderness
    • Severe allergic reactions (such as sudden swelling of the face, leading to breathing difficulties, or low blood pressure, which may cause fainting or collapse)
    • Frequent infections such as high fever, sore throat, or ulcers in the mouth or throat
    • Bleeding or bruising easily
    • Severe skin blisters with oral sores
    • Signs of liver disease (yellowing of the skin and eyes, dark urine, and tiredness)
    • Signs of serious skin reactions (such as erythema multiforme, Stevens-Johnson syndrome, or toxic epidermal necrolysis causing severe skin redness with blistering or peeling, bleeding in the lips, eyes, mouth, nose, and genitals with a high fever, and joint pains)
    • Signs of decreased magnesium levels in the blood (such as fatigue, tetany, delirium, convulsions, dizziness, and ventricular arrhythmia)

    How To Manage Side Effects

    Bloating

    Eat slowly and take smaller, more frequent meals, which can aid digestion and reduce gas formation. Exercise Regularly. Avoid common triggering foods like beans, lentils, carbonated beverages, fatty foods, and certain vegetables like broccoli, cabbage, and onions. Drinking plenty of water helps in the digestion process and can prevent constipation, which can contribute to flatulence. Take probiotics to help balance gut bacteria and improve digestion. Consult your doctor if flatulence persists.

    Constipation

    Increase fiber intake through fruits, vegetables, and whole grains. Stay hydrated by drinking plenty of water. Maintain regular meal times and avoid skipping meals. Exercise regularly to promote bowel movements. Establish a bathroom routine and avoid ignoring the urge to go. Avoid processed foods and prioritize probiotic-rich foods for gut health. Consult your doctor if constipation persists.

    Diarrhea

    Drink plenty of clear fluids, like water, diluted fruit juices, or oral rehydration solutions, to stay hydrated. Avoid alcohol, caffeine, and very sugary drinks, as they can worsen dehydration. Eat bland foods like bananas, rice, applesauce, and toast. These are easy to digest and can help firm up the stools. Probiotics, found in yogurt or supplements, may help restore the balance of gut bacteria. Practice good hand hygiene to prevent the spread of infection. Consult your doctor if diarrhea worsens.

    Dizziness Or Drowsiness

    Ensure proper hydration, as dehydration can cause dizziness. Avoid excessive caffeine, alcohol, and high-sodium foods, which can exacerbate symptoms. Engage in physical therapy or vestibular rehabilitation exercises designed to improve balance and reduce dizziness. Move slowly when changing positions, such as standing up or lying down, to avoid triggering dizziness. Practice relaxation techniques such as deep breathing, meditation, or yoga to manage stress, which can contribute to dizziness. Consult your doctor if dizziness persists.

    Headache

    Ensure adequate fluid intake, as dehydration can cause headaches. Maintain a consistent sleep schedule, aiming for 7-9 hours of quality sleep per night. Eat balanced meals at regular intervals to avoid blood sugar fluctuations that can trigger headaches. Practice relaxation techniques such as meditation, yoga, or deep breathing exercises to reduce stress levels. Engage in regular physical exercise, which can help reduce the frequency and severity of headaches. Apply a cold pack or warm compress to the forehead or neck to alleviate pain. Consult your doctor if a headache persists.

    Stomach Pain

    Avoid spicy or fatty foods, caffeine, or alcohol that may exacerbate symptoms. Eat a bland diet consisting of easily digestible foods like rice, bananas, applesauce, and toast. Applying a heating pad or taking a warm bath can also help soothe abdominal muscles and alleviate discomfort. Drink plenty of fluids to stay hydrated but avoid excessive consumption to prevent further irritation. If stomach pain persists, consult your doctor.

    Warning & Precautions

    Pregnancy

    Contraindicated

    RABILITE LS CAPSULE is not recommended for use by pregnant women. Consult your doctor before taking RABILITE LS CAPSULE.

    Breastfeeding

    Contraindicated

    RABILITE LS CAPSULE is strictly not recommended for use by breastfeeding women. Consult your doctor before taking RABILITE LS CAPSULE.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any heavy tools or machines if you experience dizziness, drowsiness, or sleepiness after taking RABILITE LS CAPSULE.

    Alcohol

    Consult your doctor

    Avoid consumption of alcohol while taking RABILITE LS CAPSULE, as it could cause CNS depression (characterized by confusion, attention impairment, and anxiety), dizziness, and/or drowsiness. Consult your doctor before taking RABILITE LS CAPSULE.

    Kidney

    Use with Caution

    RABILITE LS CAPSULE should be taken with caution in patients with kidney disease. Consult your doctor before taking RABILITE LS CAPSULE.

    Liver

    Use with Caution

    RABILITE LS CAPSULE should be taken with caution in patients with a previous history of liver problems. Consult your doctor before taking RABILITE LS CAPSULE.

    Allergy

    Contraindicated

    Do not take RABILITE LS CAPSULE if you are allergic to levosulpiride, Rabeprazole, or other proton-pump inhibitors (Ex. pantoprazole, omeprazole, and lansoprazole).

    Lungs

    Use with Caution

    RABILITE LS CAPSULE should be taken with caution in patients with asthma or other respiratory diseases. Consult your doctor before taking RABILITE LS CAPSULE.

    Heart Disease

    Use with Caution

    RABILITE LS CAPSULE should be taken with caution in patients with heart disease. Consult your doctor before taking RABILITE LS CAPSULE.

    Use In Pediatrics

    Contraindicated

    RABILITE LS CAPSULE is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking RABILITE LS CAPSULE.

    Use In Geriatrics

    Use with Caution

    RABILITE LS CAPSULE should be used with caution in elderly patients (aged 65 years or older). Consult your doctor before taking RABILITE LS CAPSULE. Proper dose adjustments and careful monitoring are required for such patients.

    Others

    RABILITE LS CAPSULE is not recommended for use if you have:

    • Parkinson’s disease
    • History of epilepsy
    • Neuroleptic malignant syndrome (a CNS disorder characterized by high fever, stiffness of the muscles, altered mental status (paranoid behaviour), and autonomic dysfunction)
    • Breast cancer (with high levels of prolactin in the body)

    Before taking RABILITE LS CAPSULE, inform your physician if you: 

    • Have a tumour in the stomach or breast
    • Have bleeding or perforation of the gastrointestinal tract
    • Have or are at risk of developing vitamin B12 deficiency
    • Had developed any skin reactions following management with similar medicines that can reduce stomach acid
    • Are due to have a specific blood test (chromogranin A)
    • Have osteoporosis
    • Are a smoker
    • Have porphyria (a rare blood disorder)
    • Have alcohol intoxication (drinking a large amount of alcohol in a short period of time)
    • Have or had phaeochromocytoma (tumours of the adrenal gland) in the past
    • Have or had prolactinoma (a noncancerous tumour of the pituitary gland) in the past
    • Have hypokalemia (decreased potassium levels in the blood)
    • Have a neuroendocrine tumour (tumours in neuroendocrine cells)
    • Have mania or other mental disorders
    • Have painful breasts

    Interactions

    A. Drug-Drug interactions:

    • Antivirals (Ex. atazanavir, nelfinavir, saquinavir, and rilpivirine)
    • Antacids (Ex. aluminium hydroxide, magnesium hydroxide)
    • Gastroprokinetic agent (Ex. cisapride)
    • Antiulcer (Ex. sucralfate)
    • Anticholinergics (Ex. atropine, scopolamine, and homatropine)
    • Antiparkinsonian drugs (Ex. levodopa)
    • Diuretics (Ex. furosemide)
    • Corticosteroids (Ex. cortisol)
    • Laxatives (such as bisacodyl)
    • Iron salts (Ex. ferrous sulphate, ferric ammonium citrate)
    • Antihypertensives (Ex. captopril, enalapril, losartan, valsartan, diltiazem, digoxin, quinidine)
    • Selective norepinephrine reuptake inhibitors (Ex. atomoxetine)
    • Antiallergics (Ex. terfenadine)
    • Antimalarial (Ex. chloroquine)
    • Antibacterials (Ex. clarithromycin or amoxicillin)
    • Anticancer (Ex. erlotinib, dasatinib, nilotinib, methotrexate)
    • Immunosuppressants (Ex. tacrolimus or mycophenolate mofetil)
    • Antifungals (Ex. ketoconazole, itraconazole)
    • Anticoagulant (Ex. warfarin)
    • Analgesics (Ex. pregabalin, tramadol)
    • Bronchodilators (Ex. ipratropium)

    Overdosage:

    If you or anyone else accidentally takes too much RABILITE LS CAPSULE, contact your doctor immediately or go to a hospital right away.

    Synopsis

    Drug :   Levosulpiride, Rabeprazole
    Pharmacological Category :   Dopamine D2 antagonists, Proton-pump inhibitors
    Therapeutic Indication :   Peptic ulcer, GERD, Functional dyspepsia, Diabetic gastroparesis, Zollinger-Ellison syndrome 
    Dosage Forms :   Tablet, Capsule

    More Information

    Storage

    • Keep RABILITE LS CAPSULE out of reach of children
    • Store RABILITE LS CAPSULE at room temperature

    FAQs About RABILITE LS CAPSULE

    Q: When and how should I take RABILITE LS CAPSULE?

    A: Take RABILITE LS CAPSULE on an empty stomach or as advised by your physician. Swallow the medicine as a whole, and do not crush or chew the medicine. Your doctor will decide the correct dose of RABILITE LS CAPSULE and duration of therapy for you depending upon your age, body weight, and health condition.

    Q: Can RABILITE LS CAPSULE be used in children?

    A: RABILITE LS CAPSULE is not recommended for use in children and adolescents (aged below 18 years). Kindly consult your child’s doctor if your child experiences any symptoms of gastro-oesophageal reflux disease (such as nausea, discomfort in the upper stomach, heartburn, burping, etc.).

    Q: Can I consume alcohol while taking RABILITE LS CAPSULE?

    A: No, avoid consumption of alcohol while taking RABILITE LS CAPSULE, as it could cause CNS depression (characterized by confusion, attention impairment, and anxiety), dizziness, and/or drowsiness. Also, if you are a chronic alcoholic or suffering from acute alcohol intoxication, please inform your doctor as a precaution before taking RABILITE LS CAPSULE.

    Q: Can I drive or operate machinery after taking RABILITE LS CAPSULE?

    A: RABILITE LS CAPSULE may cause dizziness in some individuals, so avoid driving or operating any tools or machines while you are feeling dizzy. Try to rest and relax. Get enough sleep. Do not consume too much alcohol, as it can aggravate your dizziness. Consult your doctor before taking RABILITE LS CAPSULE.

    Q: Does prolonged use of RABILITE LS CAPSULE cause bone fractures?

    A: Yes, prolonged use of RABILITE LS CAPSULE can increase the risk of bone fracture (particularly in the hips, wrists, or spine), particularly in elderly patients and in patients with other risk factors such as having osteoporosis or taking corticosteroids. Consult your doctor before taking RABILITE LS CAPSULE. During management with RABILITE LS CAPSULE, your doctor may monitor to rule out the risk of fractures. Do not take RABILITE LS CAPSULE for a prolonged period without consulting your doctor.

    Q: What should I do if I forget to take RABILITE LS CAPSULE?

    A: You should take RABILITE LS CAPSULE immediately when you remember. If it is time for your next dose of RABILITE LS CAPSULE, skip the missed dose and follow your regular dose schedule. Do not double the dose to make up for your missed dose.

    Q: What are the common side effects of RABILITE LS CAPSULE?

    A: The most common side effects of taking RABILITE LS CAPSULE are nausea, vomiting, headache, stomach pain, diarrhea, constipation, infections, cough, or sore throat. Consult your doctor if any of the side effects worsen.

    Q: What is the RABILITE LS CAPSULE used for?

    A: RABILITE LS CAPSULE is indicated for the management of gastroesophageal reflux disease (GERD). Symptoms include heartburn, chest pain, nausea, the sensation of a lump in the throat, and stomach discomfort. It can also be used to manage peptic ulcers, Zollinger-Ellison syndrome, functional dyspepsia, and diabetic gastroparesis.

    Q: How does RABILITE LS CAPSULE work?

    A: RABILITE LS CAPSULE reduces stomach ulcers, nausea, and acid reflux. Rabeprazole acts by inhibiting the secretions of stomach acid by blocking the proton pump (H+ K+ ATPase) at the secretory surface of gastric parietal cells, and levosulpiride acts by blocking the dopamine D2 receptors in the CTZ (area in the medulla oblongata that causes vomiting when stimulated) and in the gut, thus facilitating the movement of food from the stomach into the intestines, followed by the healing of ulcers or inflammatory lesions in the stomach and in the esophagus.

    Q: Where can RABILITE LS CAPSULE be purchased?

    A: To order RABILITE LS CAPSULE online, visit the Netmeds website, search for the product, add it to your cart, and proceed to checkout. Follow the instructions for payment and delivery. Netmeds has made buying online medicines easier for consumers and is one of India's leading online pharmacies.

    References

    1. KD. Tripathi. Drugs for Peptic Ulcer and Gastroesophageal Reflux Disease. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 651-654.

    2. Gerald G. Briggs and Roger K. Freeman. P. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Pages – 3337 & -2775.

    3. E. Distrutti, S. Fiorucci, S. K. Hauer, M. O. Pensi, M. Vanasia, and A. Morelli. Effects of acute and chronic levosulpiride administration on gastric tone and perception in functional dyspepsia. Alimentary Pharmacology and Therapeutics. September 2002. [Accessed on 7th June 2024] https://onlinelibrary.wiley.com/doi/epdf/10.1046/j.1365-2036.2002.01180.x

    4. Ratnani IJ, Panchal BN, Gandhi RR, Vala AU, and Mandal K. Role of Levosulpiride in the Management of Functional Dyspepsia. Journal of Family Medicine. 2015. [Accessed on 7th June 2024] https://austinpublishinggroup.com/family-medicine/fulltext/jfm-v2-id1034.php

    5. R Lozano, MG Peralta Concha, A Montealegre, L de Leon, J Ortiz Villalba, HO Lee Esteban, M Cromeyer, JA Rivas García, A Brossa, G Lluberes, E Izquierdo Sandí and H Burgos Quirós. Effectiveness and safety of levosulpiride in the treatment of dysmotility-like functional dyspepsia. NCBI, PMC, US National Library of Medicine, National Institute of Health. March 2007. [Accessed on 7th June 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936295/

    6. C Mansi, V Savarino, S Vigneri, D Perilli, P Melga, L Sciabà, D De Martini, and G S Mela. Gastrokinetic effects of levosulpiride in dyspeptic patients with diabetic gastroparesis. NIH National Library of Medicine, National Center for Biotechnology Information, Pubmed.gov. November 1995. [Accessed on 7th June 2024] https://pubmed.ncbi.nlm.nih.gov/7485007/

    7. P W Y Lim, K L Goh. Review article: efficacy and safety of rabeprazole in treating gastroesophageal reflux disease. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed.gov. September 2004. [Accessed on 7th June 2024] https://pubmed.ncbi.nlm.nih.gov/15324384/

    8. Torrent Pharmaceuticals Ltd. Veloz L. Torrentian.com. [Revised in Match 2020]. [Accessed on 7th June 2024] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2425.pdf

    9. Cipla Ltd. Rabicip L Capsules (Rabeprazole sodium + Levosulpiride). CiplaMed.com [Revised in August 2023]. [Accessed on 7th June 2024] https://www.ciplamed.com/product-index/rabicip-l-capsules

    10. KRKA, d.d.,. Electronic Medicines Compendium (EMC). [Revised in March 2017] [Accessed on 7th June 2024] https://www.medicines.org.uk/emc/files/pil.14538.pdf

    11. Eisai R&D Management Co., Ltd. Aciphex. U. S. Food and Administration. [Revised in December 2014]. [Accessed on 7th June 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020973s035204736s005lbl.pdf

    12. Akesiss Pharma Pvt. Ltd. Rabipot LS. [Accessed on 7th June 2024] https://akesiss.com/divisions/glyvo-life/rabipot-ls/

    Useful Diagnostic Tests

    • Monsoon Gastro Infection Panel
    • Gastro / Gut Health Panel
    • Helicobacter Pylori Iga
    • Helicobacter Pylori Igg
    • Complete Blood Count (CBC)/ Hemogram
    • Healthy Midlife Checkup
    • Senior Citizen Checkup - Female
    • Senior Citizen Checkup - Male
    • Full Body Checkup - Gold

    Author Details

    Written By Dr. N. Sai Swaroop - Pharm.D
    Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS
    Last updated on 21 Jun 2024 | 05:50 PM(IST)
    Lab updated