R4CLEAR Tablet 10's
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Introduction About R4CLEAR TABLET
R4CLEAR TABLET is used in the management of asthma and chronic obstructive pulmonary disease (COPD). It can also be used to manage inflammation of the airways (such as bronchitis or cystic fibrosis) and reduce the onset of other complications caused due to mucus obstruction in the airways such as bronchospasm (paralysis of airways) and wheezing or shortness of breath. It is a combination of Acebrophylline and Acetylcysteine which belongs to the group of medicines called Bronchodilators and Mucolytics respectively.
Take R4CLEAR TABLET preferably with meals or as advised by your physician. Before taking the medicine, inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have fits, stomach ulcers, viral infections, hypertension or hyperthyroidism as a precaution.
R4CLEAR TABLET is not recommended for use in pregnant and in breastfeeding women. The most common side effects are epigastric pain, stomach discomfort, nausea, vomiting, dizziness, drowsiness, diarrhea and constipation. Consult your doctor if any of these side effects trouble you.
Uses Of R4CLEAR TABLET
It is used to manage:
- Asthma and COPD
- Bronchitis
- Cystic fibrosis
- Bronchospasm and Shortness of breath
How R4CLEAR TABLET Works
R4CLEAR TABLET is an bronchodilator with anti-inflammatory and mucolytic properties. It blocks the release of certain chemicals (such as phosphodiesterase) in the respiratory tract that triggers airway inflammation, swelling and narrowing. As a result, it widens the airways, and reduces airway inflammation. It also loosens the mucus accumulated in the airways which allows the air to pass through more freely through the airways and makes breathing easier.
How to use R4CLEAR TABLET
- Take R4CLEAR TABLET preferably with meals or as advised by your physician
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
- Your doctor will decide the correct dose and duration of therapy depending upon your age, body weight and disease condition
- Do not stop taking R4CLEAR TABLET once your symptoms subside without consulting your doctor
Side Effects Of R4CLEAR TABLET
Common side effects of R4CLEAR TABLET:
- stomach pain or discomfort, heartburn, loss of appetite
- transient nausea, vomiting
- dizziness, drowsiness
- diarrhoea, constipation
- skin rash or itching
- breathing difficulties
- nasal inflammation
- headache
Stop taking this medicine and contact your doctor immediately if you experience any of the following side effects:
- signs of allergic reaction (skin rash, itching, swelling of the face, lips, throat and tongue causing difficulty in breathing or swallowing)
Warning & Precautions
Pregnancy
ContraindicatedR4CLEAR TABLET is not recommended for use in pregnancy.
Breastfeeding
ContraindicatedR4CLEAR TABLET is not recommended for use in breastfeeding women.
Driving and Using Machines
Use with CautionR4CLEAR TABLET usually does not affect your ability to drive or operate any machinery. However, do not drive or handle any heavy tools or machines if you feel dizzy or drowsy after taking the medicine.
Kidney
Consult your doctorR4CLEAR TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems.
Liver
Consult your doctorR4CLEAR TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with hepatic dysfunction.
Allergy
ContraindicatedDo not take R4CLEAR TABLET if you are allergic to Acetylcysteine, Acebrophylline or to any other ingredients of this medicine.
Heart Disease
Consult your doctorR4CLEAR TABLET is not recommended for use in patients suffering from myocardial infarction or arrythmias. It should be used with caution in patients with heart failure or any other heart problems.
Use In Pediatrics
ContraindicatedR4CLEAR TABLET is not recommended for use in children and adolescents (aged below 18 years).
Use In Geriatrics
Use with CautionR4CLEAR TABLET should be used with caution in the elderly patients.
Others
R4CLEAR TABLET is not recommended for use if you:
- have hypotension (low blood pressure)
- have fluid and electrolyte imbalance
Before taking the medicine, inform your doctor if you:
- have chronic alcoholism (addiction to alcohol)
- have any viral infections
- have an over-active thyroid gland
- have hypertension (high blood pressure)
- have ulcers in the stomach and/or intestines
- have fits (seizures)
- have any allergic conditions
Interactions
A. Drug-Drug interactions:
Before taking R4CLEAR TABLET, inform your doctor if you are taking any of the following medicines such as:
- Anti-gout agents (Ex. allopurinol)
- H2 blockers (Ex. cimetidine)
- Antibiotics (Ex. ciprofloxacin, erythromycin, doxycycline, gentamycin, azithromycin, amoxicillin)
- Corticosteroids (Ex. Prednisolone, Dexamethasone)
- Calcium-channel blockers (Ex. diltiazem, verapamil)
- Diuretics (Ex. frusemide)
- Non-selective beta-adrenoreceptor agonist (Ex. isoprenaline)
- Oral contraceptives (Ex. ethinylestradiol)
- Benzimidazoles (Ex. thiabendazole)
- Activated charcoal
- Glyceryl trinitrate (Ex. Nitrates)
Overdosage:
If you or anyone else accidentally took more R4CLEAR TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include nausea, vomiting, upper stomach pain, restlessness, fits, fast heart rate and hyperactivity.
Synopsis
| Drug | : | Acebrophylline, N-Acetylcysteine |
| Pharmacological Category | : | Methylxanthines, Mucolytics |
| Therapeutic Indication | : | Asthma, COPD, Bronchitis |
| Dosage Forms | : | Tablet, Capsule |
FAQs About R4CLEAR TABLET
Q: How R4CLEAR TABLET works?
A: R4CLEAR TABLET widens the airways and reduces airway inflammation. It also loosens the mucus accumulated in the airways which allows the air to pass through more freely through the airways and makes breathing easier.
Q: What is the use of R4CLEAR TABLET?
A: It is used to manage asthma, COPD and bronchitis (inflammation of the airways). It can also reduce unpleasant symptoms associated with bronchospasm such as wheezing.
Q: Can I take R4CLEAR TABLET daily?
A: R4CLEAR TABLET is generally prescribed as one or two doses per day. However, your doctor will decide the number of doses per day depending upon your age, body weight and disease condition.
Q: How long does it take for R4CLEAR TABLET to start working?
A: R4CLEAR TABLET may start working within 2 hours of oral administration. However, it may take 2 weeks for R4CLEAR TABLET to show improvements in your condition. Therefore, take the medicine regularly as informed by your doctor without fail to achieve better results.
Q: Is R4CLEAR TABLET effective?
A: Yes. R4CLEAR TABLET effectively controls the symptoms of asthma, COPD and bronchitis, by blocking the release of certain chemicals (phosphodiesterase) in the respiratory tract that triggers the allergic and inflammatory response. It also loosens the mucus and manages the narrowing of the airway tract which makes breathing easier.
Q: What will happen if I consume a high dose of R4CLEAR TABLET than prescribed by my doctor?
A: Do not consume a higher dose of R4CLEAR TABLET than the one prescribed by your doctor, as it may lead to unwanted side effects.
Q: Is R4CLEAR TABLET safe?
A: R4CLEAR TABLET is considered safe at doses prescribed by the physician. However, it may cause few side effects such as epigastric pain, stomach discomfort, nausea, vomiting, dizziness, drowsiness, diarrhea and constipation in some individuals.
Q: What should I do if I forgot to take a dose of R4CLEAR TABLET?
A: If you forgot to take a dose of R4CLEAR TABLET, take it as soon as possible. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times.
Q: Will taking a higher dose of R4CLEAR TABLET be more effective?
A: No. Do not take a higher dose of R4CLEAR TABLET than prescribed by your doctor, as it could lead to toxicity. Always consume the dose prescribed by your doctor. If you feel that the prescribed dose is not working for you, consult your doctor for advice.
Q: Can the use of R4CLEAR TABLET make me feel dizzy?
A: R4CLEAR TABLET may cause dizziness in some individuals. If you experience dizziness, try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Q: Does pregnant women can take R4CLEAR TABLET?
A: R4CLEAR TABLET is generally not recommended for use in pregnant women.
Q: Can R4CLEAR TABLET be used in children?
A: R4CLEAR TABLET is generally not recommended for use in children and adolescents (aged below 18 years).
Q: Can R4CLEAR TABLET make you sleepy?
A: Yes. This medicine may make you feel sleepy or drowsy. Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Q: Can R4CLEAR TABLET be used on an asthma attack?
A: No. R4CLEAR TABLET is only used to manage or manage the symptoms of asthma. If your asthma or breathing gets worse suddenly, contact your doctor immediately or go to the hospital straight away to avoid further exacerbation of the attack. Meanwhile use a fast-acting rescue inhaler along with R4CLEAR TABLET.
Q: Can I stop using R4CLEAR TABLET once my symptoms subside?
A: No. Continue to use R4CLEAR TABLET as long as your doctor prescribes it to you. Do not stop using this medicine or reduce the dose suddenly without consulting your doctor as it may make it less effective.
References
1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 219 & 224.
2. Sumit Roy Tapadar, Maumita Das, Arunabha Datta Chaudhuri, Santanu Basak, and Anil Baran Singha Mahapatra. The Effect of Acebrophylline vs Sustained Release Theophylline in Patients of COPD- A Comparative Study. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. September 2014. [Accessed on 11th January 2023] click here
3. Pureun-Haneul Lee, Jisu Hong, and An-Soo Jang. N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. February 2020. [Accessed on 11th January 2023] click here
4. Cipla Ltd. Mucophylin Capsules (Acebrophylline). [Revised in November 2013] [Accessed on 11th January 2023] click here
5. Ennogen Healthcare Limited. Acetylcysteine 600mg Capsules. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 11th January 2023] click here
6. LaRenon Healthcare Pvt Ltd. Aphyren-N. Acetylcysteine 600mg+Acebrophylline 100mg Tablets. 2019. [Accessed on 11th January 2023] click here
7. Leeford Healthcare Pvt Ltd. Broncofil-N. [Accessed on 11th January 2023] click here
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