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Introduction About PULMOCLEAR TABLET
PULMOCLEAR TABLET is a combination of Acebrophylline and N-Acetylcysteine which belongs to the group of medicines called Bronchodilators and Mucolytics respectively. It is used in the management of asthma and chronic obstructive pulmonary disease (COPD). It can also be used to manage inflammation of the airways (such as bronchitis or cystic fibrosis) and reduce the onset of other complications caused due to mucus obstruction in the airways such as bronchospasm (paralysis of airways) and wheezing or shortness of breath.
Take PULMOCLEAR TABLET preferably with meals or as advised by your physician. Before taking PULMOCLEAR TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have fits, stomach ulcers, viral infections, hypertension or hyperthyroidism as a precaution.
PULMOCLEAR TABLET is not recommended for use in pregnant and in breastfeeding women. The most common side effects of taking PULMOCLEAR TABLET are epigastric pain, stomach discomfort, nausea, vomiting, dizziness, drowsiness, diarrhea and constipation. Consult your doctor if any of these side effects trouble you.
Uses Of PULMOCLEAR TABLET
It is used to manage and prevent:
- Asthma & COPD
- Bronchitis (inflammation of the airways)
- Cystic Fibrosis
- Bronchospasm and shortness of breath
How PULMOCLEAR TABLET Works
PULMOCLEAR TABLET is a bronchodilator with anti-inflammatory and mucolytic properties. It blocks the release of certain chemicals (such as phosphodiesterase) in the respiratory tract that triggers airway inflammation, swelling and narrowing. As a result, it widens the airways, and reduces airway inflammation. It also loosens the mucus accumulated in the airways which allows the air to pass through more freely through the airways and makes breathing easier.
How to use PULMOCLEAR TABLET
Take PULMOCLEAR TABLET preferably with meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration of therapy depending upon your age, body weight and disease condition.
Do not stop taking PULMOCLEAR TABLET once your symptoms subside without consulting your doctor.
Side Effects Of PULMOCLEAR TABLET
Common
- stomach pain or discomfort, heartburn, loss of appetite
- transient nausea, dizziness
- vomiting, diarrhoea, constipation
- drowsiness
- skin rash or itching
- breathing difficulties
- nasal inflammation
Uncommon
- ringing in the ears (tinnitus)
- headache
- increased heart rate
- swelling or lips
- fever
- low blood pressure
Rare
- indigestion
- shortness of breath
- numbness of arm and legs
- lack of sleep
- fast heart rate
- high or low blood pressure
- sugar in urine
- increased blood sugar levels
Stop taking this medicine and contact your doctor immediately if you experience any of the following side effects:
- signs of allergic reaction (such as skin rash, itching, swelling of the face, lips, throat and tongue causing difficulty in breathing or swallowing)
- severe allergic skin reactions (such as skin rash, redness, blistering and peeling of skin, ulcers especially in areas such as face, genitals, nose, mouth or lips along with fever and flu-like symptoms)
How To Manage Side Effects
Nausea and Vomiting
Take PULMOCLEAR TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Warning & Precautions
Pregnancy
PULMOCLEAR TABLET is not recommended for use in pregnancy. Therefore, consult your doctor before taking it.
Breastfeeding
PULMOCLEAR TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
PULMOCLEAR TABLET usually does not affect your ability to drive or operate any machinery. However, do not drive or handle any heavy tools or machines if you feel dizzy or drowsy after taking PULMOCLEAR TABLET.
Kidney
PULMOCLEAR TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems. Therefore, consult your doctor before taking it.
Liver
PULMOCLEAR TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with hepatic dysfunction. Therefore, consult your doctor before taking it.
Allergy
Do not take PULMOCLEAR TABLET if you are allergic to N-Acetylcysteine, Acebrophylline or to any other methylxanthines (such as theophylline, doxophylline).
Heart Disease
PULMOCLEAR TABLET is not recommended for use in patients suffering from myocardial infarction or arrythmias. It should be used with caution in patients with heart failure or any other heart problems. Therefore, consult your doctor before taking it.
Others
PULMOCLEAR TABLET is not recommended for use if you:
- have hypotension (low blood pressure)
- have fluid and electrolyte imbalance
Before taking PULMOCLEAR TABLET, inform your doctor if you:
- have chronic alcoholism (addiction to alcohol)
- have any viral infections
- have an over-active thyroid gland
- have hypertension (high blood pressure)
- have ulcers in the stomach and/or intestines
- have fits (seizures)
- have any allergic conditions
Use in paediatrics:
PULMOCLEAR TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Use in geriatrics:
PULMOCLEAR TABLET should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.
Interactions
A. Drug - Drug interactions:
Before taking PULMOCLEAR TABLET, inform your doctor if you are taking any of the following medicines such as:
- allopurinol (a medicine used to manage gout)
- cimetidine (a medicine used to manage stomach ulcers)
- medicines used to manage bacterial infections (such as ciprofloxacin, erythromycin, doxycycline, gentamycin, azithromycin, amoxicillin)
- corticosteroids (used to manage pain and inflammation) such as prednisolone
- diltiazem, verapamil (a medicine used to manage heart problems)
- frusemide (a medicine used to reduce edema and blood pressure by increasing urine output)
- isoprenaline (a medicine used to manage slow heart rate)
- oral contraceptives (birth control pills) such as ethinylestradiol
- thiabendazole (a medicine used to manage worm infections)
- medicines used to manage cough (such as dexamethasone)
- activated charcoal (a medicine used to manage poisoning)
- glyceryl trinitrate (a medicine used to manage chest pain)
Overdosage:
If you or anyone else accidentally took more PULMOCLEAR TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include nausea, vomiting, upper stomach pain, restlessness, fits, fast heart rate and hyperactivity.
Synopsis
| Drug | : | Acebrophylline, N-Acetylcysteine |
| Pharmacological Category | : | Methylxanthines, Mucolytics |
| Therapeutic Indication | : | Asthma, COPD, Bronchitis |
| Dosage Forms | : | Tablet, Capsule |
More Information
- Keep PULMOCLEAR TABLET out of reach of children
- Store PULMOCLEAR TABLET at room temperature
FAQs About PULMOCLEAR TABLET
Q: How PULMOCLEAR TABLET works?
A: PULMOCLEAR TABLET widens the airways and reduces airway inflammation. It also loosens the mucus accumulated in the airways which allows the air to pass through more freely through the airways and makes breathing easier.
Q: What is the use of PULMOCLEAR TABLET?
A: PULMOCLEAR TABLET is used to manage asthma, COPD and bronchitis (inflammation of the airways). It can also reduce unpleasant symptoms associated with bronchospasm such as wheezing.
Q: Can I take PULMOCLEAR TABLET daily?
A: PULMOCLEAR TABLET is generally prescribed as one or two doses per day. However, your doctor will decide the number of doses per day depending upon your age, body weight and disease condition.
Q: How long does it take for PULMOCLEAR TABLET to start working?
A: PULMOCLEAR TABLET may start working within 2 hours of oral administration. However, it may take 2 weeks for PULMOCLEAR TABLET to show improvements in your condition. Therefore, take PULMOCLEAR TABLET regularly as informed by your doctor without fail to achieve better results.
Q: Is PULMOCLEAR TABLET effective?
A: Yes. PULMOCLEAR TABLET effectively controls the symptoms of asthma, COPD and bronchitis, by blocking the release of certain chemicals (phosphodiesterase) in the respiratory tract that triggers the allergic and inflammatory response. It also loosens the mucus and manages the narrowing of the airway tract which makes breathing easier.
Q: What will happen if I consume a high dose of PULMOCLEAR TABLET than prescribed by my doctor?
A: Do not consume a higher dose of PULMOCLEAR TABLET than the one prescribed by your doctor, as it may lead to unwanted side effects. Your doctor will decide the correct dose for you, depending on your age and disease condition. If the prescribed dose, is not working for you, consult your doctor for advice.
Q: Is PULMOCLEAR TABLET safe?
A: PULMOCLEAR TABLET is considered safe at doses prescribed by the physician. However, it may cause few side effects such as epigastric pain, stomach discomfort, nausea, vomiting, dizziness, drowsiness, diarrhea and constipation in some individuals. Consult your doctor if any of these side effects trouble you.
Q: What should I do if I forgot to take a dose of PULMOCLEAR TABLET?
A: If you forgot to take a dose of PULMOCLEAR TABLET, take it as soon as possible. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of PULMOCLEAR TABLET to compensate the missed dose.
Q: Will taking a higher dose of PULMOCLEAR TABLET be more effective?
A: No. Do not take a higher dose of PULMOCLEAR TABLET than prescribed by your doctor, as it could lead to toxicity. Always consume the dose prescribed by your doctor. If you feel that the prescribed dose is not working for you, consult your doctor for advice.
Q: Can the use of PULMOCLEAR TABLET make me feel dizzy?
A: PULMOCLEAR TABLET may cause dizziness in some individuals. If you experience dizziness, try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Q: I’m pregnant. Can I take PULMOCLEAR TABLET?
A: PULMOCLEAR TABLET is generally not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
Q: Can PULMOCLEAR TABLET be used in children?
A: PULMOCLEAR TABLET is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Q: Can PULMOCLEAR TABLET make you sleepy?
A: Yes. This medicine may make you feel sleepy or drowsy. Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Q: Can PULMOCLEAR TABLET be used on an asthma attack?
A: No. PULMOCLEAR TABLET is only used to manage or manage the symptoms of asthma. If your asthma or breathing gets worse suddenly, contact your doctor immediately or go to the hospital straight away to avoid further exacerbation of the attack. Meanwhile use a fast-acting rescue inhaler along with PULMOCLEAR TABLET.
Q: Can I stop using PULMOCLEAR TABLET once my symptoms subside?
A: No. Continue to use PULMOCLEAR TABLET as long as your doctor prescribes it to you. Do not stop using this medicine or reduce the dose suddenly without consulting your doctor as it may make it less effective.
References
1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 219 & 224.
2. Sumit Roy Tapadar, Maumita Das, Arunabha Datta Chaudhuri, Santanu Basak, and Anil Baran Singha Mahapatra. The Effect of Acebrophylline vs Sustained Release Theophylline in Patients of COPD- A Comparative Study. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. September 2014. [Accessed on 11th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225926/
3. Pureun-Haneul Lee, Jisu Hong, and An-Soo Jang. N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. February 2020. [Accessed on 11th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487305/
4. Cipla Ltd. Mucophylin Capsules (Acebrophylline). [Revised in November 2013] [Accessed on 11th January 2023] https://www.ciplamed.com/print-product-pdf/24147
5. Ennogen Healthcare Limited. Acetylcysteine 600mg Capsules. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 1th January 2023] https://www.medicines.org.uk/emc/files/pil.11586.pdf
6. LaRenon Healthcare Pvt Ltd. Aphyren-N. Acetylcysteine 600mg+Acebrophylline 100mg Tablets. 2019. [Accessed on 11th January 2023] https://www.larenon.com/wp-content/uploads/2020/06/1.-Aphyren-N-LBL_ctc.pdf
7. Leeford Healthcare Pvt Ltd. Broncofil-N. [Accessed on 11th January 2023] https://www.leeford.in/product/566/broncofil-n
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