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INTRODUCTION
PTU 50MG TABLET contains Propylthiouracil which belongs to the group of medicines called Antithyroid agents. PTU 50MG TABLET is used to treat hyperthyroidism, which occurs due to excess production of thyroxine hormone in affected individuals.
PTU 50MG TABLET is also used to treat Grave’s disease, thyrotoxic crisis, and thyrotoxicosis which are conditions that occur when thyroid hormone is produced extremely high in affected individuals. The medicine is also used to lower very high levels of thyroid hormone in patients scheduled for surgery, and/or radioactive iodine treatment.
PTU 50MG TABLET is not recommended for use in patients allergic to Propylthiouracil. Before taking PTU 50MG TABLET, inform your doctor if you are intolerant to certain sugars such as lactose, and/or have kidney/liver problems.
PTU 50MG TABLET should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. It is also advised to be used with caution in breastfeeding women.
PTU 50MG TABLET is advised to be used with caution in children and adolescents (aged 6 to 18 years) and is also advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor.
The most common side effects of taking PTU 50MG TABLET are stomach upset, and rash. Consult your doctor if any of these symptoms worsens.
USES OF PTU 50MG TABLET
- Treats hyperthyroidism
- Treats Grave’s disease, thyrotoxic crisis, and thyrotoxicosis (conditions that occur due to excess synthesis of thyroid hormone) in affected individuals
- Helps to lower very high levels of thyroid hormone in patients scheduled for surgery/radioactive iodine treatment
HOW PTU 50MG TABLET WORKS
PTU 50MG TABLET works by inhibiting the production of thyroid hormone in the thyroid gland which results in low thyroxine hormone level in the body thus treating hyperthyroidism and its associated symptoms in affected individuals.
DIRECTIONS FOR USE
Take PTU 50MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
SIDE EFFECTS OF PTU 50MG TABLET
COMMON
- stomach upset
- rash
RARE
- agranulocytosis (condition marked by extremely low white blood cells)
- aplastic anemia (condition marked by inability of the body to produce new blood cells)
- nephritis (inflammation of kidneys)
- hepatitis (inflammation of liver).
Stop taking PTU 50MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of liver disease such as nausea, vomiting, diarrhea, yellow discolorations of skin/eyes, dark urine, pale stools, bleeding easily, itching, and/or chills
- signs of infection such as fever, sore throat, rashes, and/or ulcers in mouth/throat
- fever, joint swelling, pain, muscle aches, blood in urine, shortness of breath, and/or rash
WARNING & PRECAUTIONS
PREGNANCY
PTU 50MG TABLET should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. Consult your doctor before taking the medicine.
BREASTFEEDING
PTU 50MG TABLET should be used with caution in breastfeeding women. Consult your doctor before taking the medicine.
KIDNEY
PTU 50MG TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking PTU 50MG TABLET.
LIVER
PTU 50MG TABLET should be used with caution in patients with liver problems. Consult your doctor before taking PTU 50MG TABLET.
ALLERGY
Do not take PTU 50MG TABLET if you are allergic to Propylthiouracil, and/or any other ingredients of this medicine.
OTHERS
Before taking PTU 50MG TABLET, inform your doctor if you:
- are intolerant to certain sugars such as lactose
- are above 40 years.
Use in Pediatrics:
PTU 50MG TABLET should be used with caution in children and adolescents (aged 6 to 18 years). Consult your doctor before taking PTU 50MG TABLET.
Use in Geriatrics:
PTU 50MG TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking PTU 50MG TABLET.
INTERACTIONS
A. Drug - Drug interactions:
Before taking PTU 50MG TABLET, inform your doctor if you are taking any of the following medicine:
- mineral supplements (containing iodine)
- theophylline (used to treat asthma)
- aminophylline (used to treat and prevent wheezing, shortness of breath)
- digoxin (to treat irregular heartbeats).
Overdosage:
If you or anyone else accidentally takes too much of PTU 50MG TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
SYNOPSIS
| Drug | : | Propylthiouracil |
| Pharmacological Category | : | Antithyroid agents |
| Therapeutic Indication | : | Hyperthyroidism |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep PTU 50MG TABLET out of reach of children
- Do not store PTU 50MG TABLET above 25?
FAQs ABOUT PTU 50MG TABLET
Q. What is PTU 50MG TABLET used for?
A. PTU 50MG TABLET is used to treat hyperthyroidism (condition marked by high thyroxine hormone) which is also used to treat Grave’s disease, thyrotoxic crisis, and thyrotoxicosis, (conditions that occur when thyroid hormone is produced extremely high) in affected individuals. The medicine is also used to lower very high levels of thyroid hormone in patients scheduled for surgery/radioactive iodine treatment.
Q. What are the common side effects of taking PTU 50MG TABLET?
A. The most common side effects of taking PTU 50MG TABLET are stomach upset, and rash. Consult your doctor if any of these symptoms worsens.
Q. How PTU 50MG TABLET should be taken?
A. Take PTU 50MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Q. What happens if PTU 50MG TABLET is taken more than its required dosage?
A. If you or anyone else accidentally takes too much of PTU 50MG TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
Q. How PTU 50MG TABLET works?
A. PTU 50MG TABLET works by inhibiting the production of thyroid hormone in the thyroid gland which results in low thyroxine hormone level in the body thus treating hyperthyroidism and its associated symptoms in affected individuals.
REFERENCES
1. K.D.Tripathi. Thyroid Hormones and Thyroid Inhibitors. Essentials of medical pharmacology. Seventh edition. 2013. Page – 253.
2. Fnu Amisha; Anis Rehman. Propylthiouracil (PTU). NIH National Library of Medicine. National center for biotechnology information. StatPearls [Internet]. June 2022. [Accessed on 12thMarch 2022] https://www.ncbi.nlm.nih.gov/books/NBK549828/
3. Bethesda. Propylthiouracil. NIH National Library of Medicine. National center for biotechnology information. LiverTox. February 2020. [Accessed on 12thMarch 2022] https://www.ncbi.nlm.nih.gov/books/NBK547973/
4. Recipharm Uppsala AB. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed on 15th June 2022] https://www.medicines.org.uk/emc/files/pil.9177.pdf
USEFUL DIAGNOSTIC TESTS
- Blood test
PRODUCT DETAILS
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