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Introduction About PROPYSALIC NF OINTMENT
PROPYSALIC NF OINTMENT is a combination of Clobetasol propionate and Salicylic acid which belongs to a group of medicines called Topical Corticosteroids and Keratolytic agents, respectively. PROPYSALIC NF OINTMENT is used to manage and provide relief from inflammatory manifestations of skin conditions such as psoriasis (skin condition marked by rash and itchiness), and eczema (skin inflammation) in affected individuals. PROPYSALIC NF OINTMENT is also used to provide relief from skin redness, itching, and/or swelling due to various skin conditions. It is also indicated for use to manage other skin conditions such as dermatoses (skin lesion), seborrheic dermatitis of scalp and/or ichthyosis vulgaris (inherited skin condition marked by dry & scaly skin) in affected individuals.
PROPYSALIC NF OINTMENT is generally not recommended for use in patients allergic to Clobetasol, and/or Salicylic acid. PROPYSALIC NF OINTMENT is advised to be used in pregnant and breastfeeding women only if it is clearly necessary. PROPYSALIC NF OINTMENT is not recommended for use in children and adolescents (aged below 12 years). The medicine is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor.
The most common side-effects associated with the use of PROPYSALIC NF OINTMENT are irritation, burning, redness, and/or stinging sensation (at the site of application), skin rash, itching, and/or peeling/ thinning of skin. Consult your doctor if any of these side effects worsens.
Uses Of PROPYSALIC NF OINTMENT
It is used to:
- manage and provide relief from inflammatory manifestations of skin conditions such as psoriasis and eczema
- provide relief from skin redness, itching, and/or swelling due to various skin conditions
- manage other skin conditions such as dermatoses, seborrheic dermatitis of scalp, and/or ichthyosis vulgaris in affected individuals
How PROPYSALIC NF OINTMENT Works
PROPYSALIC NF OINTMENT provides relief from psoriasis and eczema, where Clobetasol propionate manages inflammation by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and/or itchy. Salicylic acid softens the skin by removing dead skin cells and breaking down keratin clumps which results in reducing itchiness and redness of skin, thus providing relief from psoriasis and eczema in affected individuals.
How to use PROPYSALIC NF OINTMENT
Always apply PROPYSALIC NF OINTMENT as directed by your physician. It is for external use only. Wash your hands and apply a thin layer of medicine on the affected area. Avoid covering the affected area with airtight dressings unless recommended. Avoid applying the medicine on face, groin, or axillae. Your doctor will decide the correct dose. and duration for you depending upon your age, body weight and disease condition.
Side Effects Of PROPYSALIC NF OINTMENT
Common
- irritation, burning, redness, and/or stinging sensation at the site of application
- peeling/thinning of skin
Uncommon
- erythema (skin redness)
- telangiectasia (condition marked by small, widened blood vessels on the skin)
Stop applying PROPYSALIC NF OINTMENT and contact your doctor immediately if you experience any of the following side effects:
- blurred vision, dizziness, fainting, and/or irregular heartbeat
- irritation, and/or sensitization
How To Manage Side Effects

Skin rash Or Itching
Try to pat/tap your skin instead of scratching it. Hold a damp towel to cool your skin. Wear loose clothing and avoid tight clothes, or clothes made from wool or synthetic fabrics. Avoid using perfumed soaps, deodorants, and/or moisturizers and use a skin softener regularly. Consult your doctor if the symptom does not improve or gets worse.
Warning & Precautions

Pregnancy
Monitoring requiredPROPYSALIC NF OINTMENT should be used with caution in pregnant women only if it is clearly necessary. Consult your doctor before applying the medicine.

Breastfeeding
Monitoring requiredPROPYSALIC NF OINTMENT should be used with caution in breastfeeding women only if it is clearly necessary. Consult your doctor before applying the medicine.

Allergy
ContraindicatedDo not use PROPYSALIC NF OINTMENT if you are allergic to Clobetasol, Salicylic acid, and/or any other ingredients of this medicine.

Use In Pediatrics
ContraindicatedPROPYSALIC NF OINTMENT is not recommended for use in children and adolescents (aged below 12 years). Consult your doctor before using the medicine.

Use In Geriatrics
Use with CautionPROPYSALIC NF OINTMENT should be used with caution in elderly patients (over 65 years of age). Consult your doctor before using the medicine.
Interactions
A. Drug-Drug interactions:
Inform your doctor if you are taking any ayurvedic, homeopathic, and/or any other medicines before using PROPYSALIC NF OINTMENT.
Overdosage:
If you or anyone else applies too much of PROPYSALIC NF OINTMENT or accidentally swallows it, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
Synopsis
Drug | : | Clobetasol propionate, Salicylic acid |
Pharmacological Category | : | Topical Corticosteroids, Keratolytic agent |
Therapeutic Indication | : | Psoriasis, Eczema, Other skin conditions (such as dermatoses, seborrheic dermatitis of scalp, and/or ichthyosis vulgaris) |
Dosage Forms | : | Cream, Lotion, Ointment |
More Information
Storage
- Keep PROPYSALIC NF OINTMENT out of reach of children
- Store PROPYSALIC NF OINTMENT below 30°C
FAQs About PROPYSALIC NF OINTMENT
Q: What is PROPYSALIC NF OINTMENT used for?
A: PROPYSALIC NF OINTMENT is used to manage and provide relief from inflammatory manifestations of skin conditions such as psoriasis and eczema. It is also used to provide relief from skin redness, itching, and/or swelling which is also indicated for use to manage other skin conditions such as dermatoses, seborrheic dermatitis of scalp, and/or ichthyosis vulgaris in affected individuals.
Q: What are the side effects of PROPYSALIC NF OINTMENT?
A: The most common side-effects associated with the use of PROPYSALIC NF OINTMENT are irritation, burning, redness, and/or stinging sensation (at the site of application), skin rash, itching, and/or peeling/ thinning of skin. Consult your doctor if any of these symptoms worsens.
Q: How PROPYSALIC NF OINTMENT works?
A: PROPYSALIC NF OINTMENT provides relief from psoriasis and eczema, where Clobetasol propionate manages inflammation by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and/or itchy. Salicylic acid softens the skin by removing dead skin cells and breaking down keratin clumps which results in reducing itchiness and redness of skin, thus providing relief from psoriasis and eczema in affected individuals.
Q: How PROPYSALIC NF OINTMENT is applied?
A: Always apply PROPYSALIC NF OINTMENT as directed by your physician. It is for external use only. Wash your hands and apply a thin layer of medicine on the affected area. Avoid covering the affected area with airtight dressings unless recommended. Avoid applying the medicine on face, groin, or axillae. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Q: Can PROPYSALIC NF OINTMENT be used in pregnant and breastfeeding women?
A: Yes, PROPYSALIC NF OINTMENT can be used but with caution in pregnant and breastfeeding women only if it is clearly necessary. Consult your doctor before applying PROPYSALIC NF OINTMENT.
References
1. KD. Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page-889, 889.
2. Jana Petersen, Claudia Garbe, Sandra Wolf, Brigitte Stephan, Matthias Augustin, Kristina Hagenström. Medicinal Treatment of Elderly Psoriasis Patients before and after Entering a Nursing Home. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in September 2022] [Accessed on 16th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498407/
3. Lilit Garibyan, Albert S. Chiou, Sarina B. Elmariah. Advanced Aging Skin and Itch: Addressing an Unmet Need. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in June 2014] [Accessed on 16th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051285/
4. Ziska Pharmaceuticals Ltd. Closalic Ointment. [Accessed on 16th November 2022] http://ziskapharma.com/uploads/products/Closalic_Insert_Size.pdf
5. Sangrose Laboratories Pvt. Ltd. Closal. [Accessed on 16th November 2022] https://sangroselaboratories.com/products/
6. Swisschem Dermacare. CLOBSOL-S. [Accessed on 16th November 2022] https://www.swisscosmed.in/product/clobetasol-salicylic-acid-3
7. Care Formulation Labs Pvt. Ltd. MYSELIC. [Accessed on 16th November 2022] https://careformulationlabs.com/product/myselic/
8. Velite. CLOBISOL-S LOTION. [Accessed on 16th November 2022] https://velite.in/index.php?route=product/product&product_id=183
9. Ederma Pharma India Pvt Ltd. ECZIVATE-S 6% LOTION. [Accessed on 16th November 2022] https://edermapharma.com/product/eczivate-s-6-lotion/
10. QndQ Derma. Comply-S. [Accessed on 16th November 2022] https://www.qndqdermacare.com/product/comply-s
11. Hanuchem Laboratories. Comply-S. [Accessed on 16th November 2022] https://www.hanuchemlabs.com/ointemnts
12. Innovative Pharmaceuticals Pvt Ltd. Clotrol-S Ointment. [Accessed on 16th November 2022] https://www.innovativepharma.in/product/clotrol-s-ointment/
Useful Diagnostic Tests
- Patch test
- Skin biopsy