INTRODUCTION

PREGEB 75MG contains Pregabalin which belongs to a group of medicines known as anticonvulsants. It is used to treat epilepsy, neuropathic pain and generalized anxiety disorder (GAD). Epilepsy is a disorder in which nerve cell activity in brain is disturbed, causing seizures. This medicine is used to treat the certain form of epilepsy (partial seizures with or without secondary generalization) in adults. Damage to nerves outside of the brain and spinal cord leads to peripheral and central neuropathic pain. This medicine is used to treat pain caused by damaged nerves. Neuropathic pain may have an impact on physical and social functioning and overall quality of life associated with the mood changes, disturbances in sleep and fatigue.

Generalized Anxiety Disorder (GAD) is characterized by the persistent and excessive worry about a number of different things. PREGEB 75MG efficiently helps in reducing the psychological symptoms of this disorder. Always take PREGEB 75MG exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water. Do not drive or operate any machinery while taking this medicine, it may make you feel drowsy. This medicine is not recommended for children and adolescents below 18 years of age, pregnant or breastfeeding. Before taking, tell your doctor if you have liver, kidney or heart problems. The common side effects are dizziness, drowsiness, headache and diarrhea.

USES OF PREGEB 75MG

• Treat epilepsy, neuropathic pain and Generalized Anxiety Disorder (GAD) in adults

HOW PREGEB 75MG WORKS

Pregabalin works by reducing abnormal electrical activity in the brain and stops seizures. In neuropathic pain, it interferes with pain messages travelling through the brain and down the spine and blocks the pain.

DIRECTIONS FOR USE

Always take PREGEB 75MG exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water.

SIDE EFFECTS OF PREGEB 75MG

HOW TO MANAGE SIDE EFFECTS

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Diarrhea:

Drink lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicines without consulting your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking:

• other medicines which have or had sedative effects (including opioids)
• oxycodone (used as a painkiller)
• lorazepam (used for treating anxiety)

SYNOPSIS

MORE INFORMATION

Store at room temperature 15-25°C and keep out of reach of children.

FAQs ABOUT PREGEB 75MG

Can PREGEB 75MG be used in pregnant women?

No. It is not recommended for use in the pregnant women. Consult your doctor before taking this medicine.

How does PREGEB 75MG work for pain?

It works by changing the way that nerves send messages to your brain. If the messages are reduced, then pain will be reduced.

REFERENCES

1. Goodman and Gilman’s: The Pharmacological Basis of Therapeutics. Chapter - 21 - Pharmacotherapy of the epilepsies; 12th ed. New York, New York: McGraw-Hill Medical, 2011. Page – 599.

2. Charles P Taylor, Timothy Angelotti, Eric Fauman; Pharmacology and mechanism of action of pregabalin: the calcium channel alpha2-delta (alpha2-delta) subunit as a target for antiepileptic drug discovery; [Published on 2007] https://pubmed.ncbi.nlm.nih.gov/17126531/

3. Parke-Davis Div of Pfizer Inc; U.S. Food & Drug Administration; [Revised on 06/2020] [Accessed 19 Oct 2020] http://labeling.pfizer.com/ShowLabeling.aspx?id=9678

4. Accord Healthcare Limited; Electronic Medicines Compendium (EMC); [Revised on 07/2020] [Accessed 19 Oct 2020] https://www.medicines.org.uk/emc/files/pil.7448.pdf

5. Pfizer Pharmaceuticals LLC; Parke-Davis Div of Pfizer Inc;U.S. Food & Drug Administration; [Revised on 06/2011] [Accessed 19 Oct 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021446s026,022488s005lbl.pdf