PRAMI 0.25 Tablet 10's

Parkinsonism Rx required
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Best Price*  ₹ 50.16
MRP ₹62.70
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: D D Pharmaceuticals Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

PRAMI 0.25 contain Pramipexole dihydrochloride which belongs to a group of medicine called dopamine agonists. Stimulation of the dopamine receptors triggers nerve impulses in the brain that help to control body movements. It is used to treat the symptoms of primary Parkinson’s disease in adults. It can be used alone or in combination with levodopa (another medicine for Parkinson’s disease). It works by increasing the action of dopamine, a chemical messenger that is needed to control movement in the brain.

Parkinson's disease is a disorder of the central nervous system that affects movement, often including tremors. Nerve cell damage in the brain causes dopamine levels to drop, leading to the symptoms of Parkinson's. Parkinson's often starts with a tremor in one hand. Other symptoms are slow movement, stiffness, and loss of balance.

Always take PRAMI 0.25 exactly as your doctor has told you. This medicine must be taken with or without food. The most common side effects are dizziness, nausea, hallucinations, sleeplessness (insomnia), peripheral oedema, constipation, vomiting and headache. This medicine is strictly not recommended for use in children and adolescents under 18 years. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.

USES OF PRAMI 0.25

  • Treat the symptoms of primary Parkinson’s disease in adults

HOW PRAMI 0.25 WORKS

PRAMI 0.25 works by increasing the action of dopamine, a chemical messenger that is needed to control movement in the brain.

DIRECTIONS FOR USE

Always take PRAMI 0.25 exactly as your doctor has told you. This medicine must be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF PRAMI 0.25

COMMON

  • dyskinesia
  • dizziness, tiredness, confusion
  • nausea
  • urge to behave in an unusual way
  • hallucinations
  • sleeplessness (insomnia)
  • peripheral oedema
  • headache
  • hypotension 
  • abnormal dreams
  • constipation
  • visual impairment
  • vomiting 
  • weight loss including decreased appetite

RARE

  • mania

HOW TO MANAGE SIDE EFFECTS

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Nausea:

Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Constipation: 

Take fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

WARNING & PRECAUTIONS

PREGNANCY

PRAMI 0.25 is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

PRAMI 0.25 is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machine while taking this medicine since it may cause hallucinations, sleepiness.

ALCOHOL

Consumption of alcohol is not recommended during treatment with PRAMI 0.25.

KIDNEY

PRAMI 0.25 should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.

LIVER

PRAMI 0.25 should be used with caution in patients suffering from liver function impairment or active liver diseases.

ALLERGY

Do not take PRAMI 0.25 if you are allergic (hypersensitive) to Pramipexole dihydrochloride or any other ingredients in this medicine.

OTHERS

Tell your doctor if you have or had a condition such as,

  • hallucinations (seeing, hearing, or feeling things that are not there)
  • dyskinesia (e.g. abnormal, uncontrolled movements of the limbs)
  • have advanced Parkinson’s disease
  • dystonia, axial dystonia (inability of keeping your body and neck straight and upright)
  • experience forward flexion of the head and neck (also called antecollis), forward bending of the lower back (also called camptocormia) or sidewards bending of the back (also called pleurothotonus or Pisa Syndrome)
  • sleepiness and episodes of suddenly falling asleep
  • psychosis (e.g. comparable with symptoms of schizophrenia)
  • vision impairment

INTERACTIONS

Talk to your doctor if you are taking,

  • cimetidine (used to treat excess stomach acid and stomach ulcers)
  • amantadine (used to treat Parkinson’s disease)
  • mexiletine (used to treat irregular heartbeats)
  • zidovudine (used to treat AIDS)
  • cisplatin (used to treat various types of cancers)
  • quinine (used to prevent painful night-time leg cramps and for the treatment of a type of malaria known as falciparum malaria (malignant malaria))
  • procainamide (used to treat irregular heartbeat)
  • levodopa

SYNOPSIS

Drug :   Pramipexole
Pharmacological Category :   Dopamine agonists
Therapeutic Indication :   Parkinson’s disease
Dosage Forms :   Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT PRAMI 0.25

Is PRAMI 0.25 a muscle relaxant?

No, it is not a muscle relaxant. It helps in improving movements and muscle control in Parkinson’s disease. It is a dopamine agonist and acts on dopamine receptors.

Does PRAMI 0.25 make you sleepy?

Yes, it may cause sleepiness. You may also experience sudden episodes of falling asleep. If it occurs, restrict driving and using heavy machinery, consult your doctor.

Can I take PRAMI 0.25 during breast feeding?

No, it is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

REFERENCES

1. Bertram G. Katzung, Pharmacologic Management of Parkinsonism & Other Movement Disorders, Basic & Clinical Pharmacology, Fourteenth Edition, 2015. Page – 498.

2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page – 3202-3204.

3. Radu Constantinescu. Update on the use of pramipexole in the treatment of Parkinson’s disease. US National Library of Medicines, National Institutes of Health. Apr 2008. [Accessed 26 Nov 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518382/

4. Accord Healthcare Limited; Electronic Medicines Compendium (EMC); [Revised on Nov 2020] [Accessed 26 Nov 2020] https://www.medicines.org.uk/emc/files/pil.7307.pdf

PRODUCT DETAILS

    Net Qty
    1
    Item Weight
    17.5
    Ingredient
    PRAMIPEXOLE 0.25 mg
    Hsn Code
    30049099
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