Pirahenz Injection 15ml

Introduction About PIRAHENZ INJECTION

PIRAHENZ INJECTION contains Piracetam which belongs to the group of medicines known as Nootropics. It is used in the management of myoclonus of cortical origin in combination with other anti-myoclonic therapies. Myoclonus is a sudden, involuntary muscle jerk, shake or spasm that may be caused due to disturbance in the brain and nervous system.      

Before receiving PIRAHENZ INJECTION, inform your doctor if you have severe kidney disease, liver problems, gastrointestinal ulcer, history of cerebral hemorrhage, severe bleeding and are undergoing any major surgery including dental surgery.   

PIRAHENZ INJECTION is not recommended for use in pregnant and breast-feeding women unless advised by the doctor.  

PIRAHENZ INJECTION is not recommended for use in children (below 16 years of age). It should be used with caution in elderly patients. Consult your doctor before receiving this medicine.

The common side effects of receiving PIRAHENZ INJECTION are abnormal movements, nervousness and weight gain. Inform your doctor if any of the side effects worsen.    

Uses Of PIRAHENZ INJECTION

• Manage myoclonus (sudden, involuntary muscle jerk, shake or spasm)

How PIRAHENZ INJECTION Works

PIRAHENZ INJECTION is a derivative of the neurotransmitter γ-aminobutyric acid (GABA) which improves membrane stability and fluidity in brain thereby restoring the neurotransmission via glutamatergic and cholinergic (ACh) receptors resulting in controlled movements. 

How to use PIRAHENZ INJECTION

PIRAHENZ INJECTION should be only given by a doctor or a nurse. It should be given either intravenously (in the vein) or intramuscularly (in the muscle). Your doctor will decide the correct dose and duration of PIRAHENZ INJECTION for you depending upon your age, body weight and disease condition.

Side Effects Of PIRAHENZ INJECTION

How To Manage Side Effects

Weakness: 

Drink plenty of fluid and eat balanced diet and frequent meals. Follow regular sleep schedule. Inform your doctor if the symptom does not improve.

Warning & Precautions

Pregnancy

PIRAHENZ INJECTION is not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before receiving this medicine. 

Breastfeeding

PIRAHENZ INJECTION is not recommended for use in breastfeeding woman as it is passes through breastmilk. Discuss the risks and benefits with your doctor before receiving this medicine.  

Alcohol

Avoid consumption of alcohol while receiving PIRAHENZ INJECTION.

Kidney

PIRAHENZ INJECTION is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with renal insufficiency. Consult your doctor before receiving this medicine. 

Liver

PIRAHENZ INJECTION is not recommended for use in patients having liver impairment. Consult your doctor before receiving this medicine.

Allergy

Do not receive PIRAHENZ INJECTION if you are allergic to Piracetam, other pyrrolidone derivatives (such as levetiracetam) or any other ingredients of this medicine.    

Interactions

A. Drug-Drug interactions:

Before receiving PIRAHENZ INJECTION, inform your doctor if you are taking any of the following medicines:

• thyroid hormones (medicine used to manage hypothyroidism)
• anticoagulants such as aceno-coumarol (medicine used to manage clotting of blood)
• carbamazepine, phenytoin, phenobarbitone, valproate (medicine used to control fits or seizures)

Overdosage:

PIRAHENZ INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor if you experience any unusual symptoms such as bloody diarrhea with abdominal pain.

Synopsis

More Information

• Store below 25°C

FAQs About PIRAHENZ INJECTION

What is PIRAHENZ INJECTION used for?

This medicine is used in the management of myoclonus which is a sudden, involuntary muscle jerk, shake or spasm that may be caused due to disturbance in the brain and nervous system. 

Can PIRAHENZ INJECTION be used in patients with kidney problems?

PIRAHENZ INJECTION is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with renal insufficiency. Your doctor may adjust the dose based on functioning of the kidney. Consult your doctor before receiving this medicine.  

How does PIRAHENZ INJECTION work?

PIRAHENZ INJECTION is a derivative of the neurotransmitter γ-aminobutyric acid (GABA) which improves membrane stability and fluidity in brain thereby restoring the neurotransmission via glutamatergic and cholinergic (ACh) receptors resulting in controlled movements.

Can PIRAHENZ INJECTION be used in pregnant women?

PIRAHENZ INJECTION is not recommended for use in pregnant women unless advised by the doctor. Consult your doctor before receiving this medicine if you are pregnant or planning to get pregnant.

Can PIRAHENZ INJECTION be given to children?

This medicine is not recommended for use in children below 16 years of age. Your child’s doctor may prescribe a suitable medicine for your child to manage the condition. Consult your child’s doctor for advice.

References

1. KD. Tripathi. Drugs Acting on Central Nervous System. Essentials of medical pharmacology. Eighth edition. 2013. Page – 519.

2. Bengt Winblad.  Piracetam: A Review of Pharmacological Properties and Clinical Uses. NIH National Library of Medicine, National centre for biotechnology information. PubMed Central. March 2005. [Accessed on 6th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741724/

3. Pieter A. Cohen, Igor Zakharevich, BA, and Roy Gerona. Presence of Piracetam in Cognitive Enhancement Dietary Supplements. NIH National Library of Medicine, National centre for biotechnology information. PubMed Central. March 2020. [Accessed on 6th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902196/

4. Torrent Pharmaceuticals Ltd. Normabrain Injection (Piracetam) [Revised in May 2013]. [Accessed on 6th July 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/524.pdf     

Useful Diagnostic Tests

• Kidney function test

Author Details

Written By Dr. R. Dinesh John Rajkumar - Pharm.D

Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)

Last updated on 10 Oct 2022 | 04:45 PM(IST)