INTRODUCTION

PIGOLYN 5MG TABLET contains Trioxsalen which belongs to the group of medicines called Antipsoriatic agents. It is used in the treatment of vitiligo and psoriasis along with UV light.

Vitiligo is a pigmentation disorder of the skin that causes loss of skin colour in patches. Psoriasis is a skin condition that causes rashes with itchy, scaly spots on the knees, elbows, trunk, and scalp.

Your doctor may recommend you take relevant tests to understand your existing condition. After taking the medicine avoid exposure to the sun even through a window or glass for at least 8 hours.

Before taking PIGOLYN 5MG TABLET inform your doctor if you have or had an allergic reaction to sunlight, porphyria, heart or blood vessel disease, eye problems (cataract), infections, stomach pain, skin cancer or melanoma, and lupus erythematosus.

PIGOLYN 5MG TABLET is not recommended for use in pregnant women. The safety and effectiveness of this medicine in breastfeeding women have not been established yet.

The safety and effectiveness of PIGOLYN 5MG TABLET in elderly patients had not been established yet. The most common side effects of taking PIGOLYN 5MG TABLET are itching, irritation and nausea. Consult your doctor immediately or visit a nearby hospital if any of the symptoms worsen.

USES OF PIGOLYN 5MG TABLET

• Used to treat vitiligo and psoriasis

HOW PIGOLYN 5MG TABLET WORKS

PIGOLYN 5MG TABLET works by activating certain skin cells (melanocytes) and helps repigment the discolored, white patches in vitiligo. It also slows down the rapid growth of skin cells in psoriasis. This reduces scaling and thickening of the skin.

DIRECTIONS FOR USE

Always take PIGOLYN 5MG TABLET as directed by your physician. Swallow the medicine as a whole and do not crush or chew the medicine. Cover your skin for at least 8 hours by wearing protective clothing, use a sunblock product that has a skin protection factor on your lips and on those areas of your body that cannot be covered. Your doctor will decide the correct dose, duration and frequency for you depending on your age, body weight and health condition.

SIDE EFFECTS OF PIGOLYN 5MG TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea:

Avoid oily and spicy food. Eat smaller meals. Drink lots of water. Consult your doctor if symptoms do not improve.

WARNING & PRECAUTIONS

PREGNANCY

PIGOLYN 5MG TABLET is not recommended for use in pregnant women or women planning to have a baby. Consult your doctor for advice.

BREASTFEEDING

The safety and effectiveness of PIGOLYN 5MG TABLET in breastfeeding women have not been established yet. It will be given to you by the doctor after weighing the benefits and risk ratio.

ALLERGY

Do not take PIGOLYN 5MG TABLET if you are allergic to Trioxsalen or any other ingredients of this medicine.

HEART DISEASE

PIGOLYN 5MG TABLET should be used with caution in patients with heart or blood vessel disease. Consult your doctor for advice.

INTERACTIONS

A. Drug-Drug interactions:

Before using PIGOLYN 5MG TABLET inform your doctor if you are taking any herbal supplements, prescription or nonprescription medicine.

Overdosage:

If you or anyone else accidentally took more of PIGOLYN 5MG TABLET, contact your doctor immediately or visit a nearby hospital immediately if the symptoms worsen.

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Store at room temperature

FAQs ABOUT PIGOLYN 5MG TABLET

How long should I take PIGOLYN 5MG TABLET?

Your doctor will decide the dose, duration and frequency of PIGOLYN 5MG TABLET for use depending on your age, body weight and severity of your disease condition. Consult your doctor for advice.

Can I stop taking PIGOLYN 5MG TABLET if my symptoms of the disease subside?

Though the symptoms of your disease subside, do not stop taking PIGOLYN 5MG TABLET unless recommended by your doctor as the disease and its symptoms may worsen back again. Consult your doctor for advice.

Is PIGOLYN 5MG TABLET safe for use in patients with liver disease?

PIGOLYN 5MG TABLET should be used with caution in patients with liver disease. Consult your doctor before taking PIGOLYN 5MG TABLET for more information on the safety.

Can I take PIGOLYN 5MG TABLET along with food?

Yes. PIGOLYN 5MG TABLET is recommended for use to take along with meals or milk. Consult your doctor for advice before taking the medicine.

Can PIGOLYN 5MG TABLET cause side effects?

The most common side effects of taking PIGOLYN 5MG TABLET are itching, irritation and nausea. Consult your doctor immediately or visit a nearby hospital if any of the symptoms worsen.

REFERENCES

1. KD. Tripathi. Miscellaneous drugs. Essentials of medical pharmacology. 8th Edition. 2019. Page – 950.

2. O P Salo, A Lassus, J Taskinen. NIH National Library of Medicine, National center .or biotechnology information. Trioxsalen bath plus UVA treatment of psoriasis. Plasma concentration of the drug and clinical results. 1981. [Accessed on 22nd July 2022] https://pubmed.ncbi.nlm.nih.gov/6177169/

3. M Hannuksela, J Karvonen. NIH National Library of Medicine, National center for biotechnology information. Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis. [Revised on December 1978] [Accessed on 22nd July 2022] https://pubmed.ncbi.nlm.nih.gov/737133/

4. DWD Pharmaceuticals Ltd. Med India, Trioxsalen. [Accessed on 22nd July 2022] https://www.medindia.net/drug-price/trioxsalen/dsorolen-forte.htm#Warning

5. Drugbank. Trioxsalen. [Revised on September 2007] [Accessed on 22nd July 2022]  https://go.drugbank.com/drugs/DB06267

6. Albatross Pharmaceuticals. Trioxsalen. [Accessed on 22nd July 2022] http://www.albatrosspharma.com/PDFs/Trioxen.pdf

7. Ikon Remedies Pvt Ltd. Unisorlen Tablets. [Accessed on 22nd July 2022] https://www.ikonremedies.com/product/unisorlen-25-mg-tablets/

USEFUL DIAGNOSTIC TESTS

• Skin biopsy

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 26 Nov 2022 | 05:16 PM(IST)