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INTRODUCTION

PEROCLIN 2.5% GEL is a combination of Clindamycin and Benzoyl peroxide which belongs to the group of medicines called Anti-acne preparations. It is used in the treatment of mild to moderate acne in adults and in adolescents (aged 12 years or older).

Acne is a common skin problem caused due to clogging off skin pores with dead skin cells or sebum (oil produced by the skin) with or without bacterial infection. It makes the skin inflamed with redness and pustules, along with small bumps on the skin which may be whiteheads or blackheads.

Clindamycin is a topical antibiotic and benzoyl peroxide is an antibacterial agent with sebum controlling properties. Both clindamycin and benzoyl peroxide acts by stopping the growth and multiplication of the acne-causing bacteria. Additionally, benzoyl peroxide can remove the accumulated dead skin cells and excess oil from the skin pores that triggers acne breakouts.

Use PEROCLIN 2.5% GEL as directed by the physician. It is for external use only. Avoid using PEROCLIN 2.5% GEL on inflamed, irritated, or sensitive skin areas. PEROCLIN 2.5% GEL may bleach your clothes, therefore avoid the contact of PEROCLIN 2.5% GEL with coloured fabrics.

Before using PEROCLIN 2.5% GEL inform your doctor if you have recently used any medicine that contains clindamycin or erythromycin. You must also inform your doctor if you have any problems in your gut (ulcerative colitis) or are pregnant or breastfeeding as a precaution.

PEROCLIN 2.5% GEL may cause skin redness and peeling in some individuals during the first few weeks of therapy. If you experience this, stop using PEROCLIN 2.5% GEL for a short period until your skin recovers. However, consult your doctor immediately if your skin irritation becomes severe and accompanied with skin redness, dryness, itching, stinging, or burning sensation.

USES OF PEROCLIN 2.5% GEL

  • Treats mild to moderate acne in adults and in adolescents (aged 12 years or older)

HOW PEROCLIN 2.5% GEL WORKS

PEROCLIN 2.5% GEL effectively controls acne breakouts both in adults and in adolescents. It contains clindamycin and benzoyl peroxide both which acts by preventing the growth and multiplication of acne-causing bacteria. Additionally, benzoyl peroxide opens the skin pores and removes the accumulated dead skin cells and excess oil that triggers acne breakouts. Over time, it can also reduce oil production in the skin.

DIRECTIONS FOR USE

Always use PEROCLIN 2.5% GEL as directed by your physician. It is for external use only. Wash the affected area of the skin with warm water before application. Pat it dry. Apply a thin layer of PEROCLIN 2.5% GEL on the affected area. Let the medicine completely dry on your skin before applying any make-up products or cosmetics.

Do not use any cosmetics or make-up products before applying PEROCLIN 2.5% GEL. Check the label of the medicine or consult your doctor regarding the quantity of the medicine that needs to be applied.

Contact your doctor if you experience any skin dryness or irritation after using PEROCLIN 2.5% GEL. Avoid contact of PEROCLIN 2.5% GEL with eyes, ears, nose, or mouth. Your doctor will decide the duration of therapy for you depending upon your disease condition.

SIDE EFFECTS OF PEROCLIN 2.5% GEL

COMMON

  • skin redness, irritation, itching, burning or stinging sensation at the site of application
  • skin dryness, peeling of the skin, sensitivity to sunlight
  • headache

UNCOMMON

  • sensation of numbness
  • worsening of acne

RARE

Stop using PEROCLIN 2.5% GEL and contact your doctor immediately if you experience any of the following side effects:

  • signs of allergic reactions (such as swelling of your face, eyes, lips, tongue, or throat, trouble breathing, nettle rash, severe dizziness, collapse)
  • severe or prolonged diarrhea with stomach cramps
  • severe itching, or burning or peeling of the skin

HOW TO MANAGE SIDE EFFECTS

Skin rash:

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing while going outdoors. Consult your doctor for a suitable moisturizer that suits your skin. Consult your doctor if your skin condition worsens.

Sensitivity to sunlight:

Do not exposure the affected part of the skin to the direct sunlight. Use protective clothing while going outdoors. Consult your doctor if you require any sunscreen to protect your skin while going outdoors. Consult your doctor if your skin condition worsens.

WARNING & PRECAUTIONS

PREGNANCY

There are only limited data regarding the use of PEROCLIN 2.5% GEL in pregnant women. Therefore, consult your doctor before using PEROCLIN 2.5% GEL if you are pregnant or planning to become pregnant. Your doctor may prescribe you with PEROCLIN 2.5% GEL based on the risk and benefit ratio.

BREASTFEEDING

There are only limited data regarding the use of PEROCLIN 2.5% GEL in breastfeeding women. Therefore, consult your doctor before using.

ALLERGY

Do not use PEROCLIN 2.5% GEL if you are allergic to Clindamycin, Benzoyl peroxide or lincomycin.

OTHERS

Before using PEROCLIN 2.5% GEL inform your doctor if you:

  • have any skin inflammation, irritation, or photosensitivity
  • have problems in the gut (such as regional enteritis, ulcerative colitis or stomach inflammation caused due to use of antibiotics)
  • have recently used any medicine that contains clindamycin or erythromycin in it
  • have an upcoming surgery

Use in pediatrics:

PEROCLIN 2.5% GEL should be used in children and in adolescents (aged 12 years or older) only if prescribed by the physician. It is not recommended for use in children aged below12 years due to lack of safety data. Therefore, consult your doctor before using it.

Use in geriatrics:

PEROCLIN 2.5% GEL should be used with caution in elderly patients. Therefore, consult your doctor before using it.

INTERACTIONS

A. Drug-Drug Interaction:

Before using PEROCLIN 2.5% GEL inform your doctor if you are taking any of the following:

  • other medicines used for acne (such as tretinoin, isotretinoin or tazarotene)
  • erythromycin, sulfacetamide (medicines used to treat bacterial infections)
  • dapsone (a medicine used to treat leprosy)
  • general anesthetics (used for relaxing skeletal muscles before surgery) Ex. pancuronium, vercuronium
  • medicated or abrasive soaps and cleansers
  • products contain large amounts of alcohol or astringents (Ex. skin cleansers or toners)

Overdosage:

Excessive application of PEROCLIN 2.5% GEL may cause skin irritation and dryness. If this happened, rinse it off with warm water. If irritation persists, stop using PEROCLIN 2.5% GEL for a few days or until irritation subsides or consult your doctor if necessary.

SYNOPSIS

Drug :  

Clindamycin, Benzoyl peroxide

Pharmacological Category :  

Lincomycin antibiotics, Antibacterial agents

Therapeutic Indication :   Acne
Dosage Forms :  

Gel, Cream, Gel (Topical)

MORE INFORMATION

  • Keep PEROCLIN 2.5% GEL out of reach of children
  • Store PEROCLIN 2.5% GEL in a cool, dry place or in a refrigerator (2-8?) depending upon the instructions mentioned in the label
  • Avoid contact of PEROCLIN 2.5% GEL with eyes, ears, nose, or mouth. If contact happens accidentally, rinse it off with warm water
  • Avoid contact of PEROCLIN 2.5% GEL with coloured fabrics, including clothing, towels, bed linen, furniture or carpeting as it may bleach them

FAQs ABOUT PEROCLIN 2.5% GEL

How long does it take for PEROCLIN 2.5% GEL to show the results?

It may take up to 2-3 weeks for PEROCLIN 2.5% GEL to improve your acne. However, this period may vary from patient-to-patient depending upon the severity of acne. Therefore, regularly use PEROCLIN 2.5% GEL for the stipulated duration mentioned by your doctor.

Will PEROCLIN 2.5% GEL be more effective if I overuse it?

Do not overuse PEROCLIN 2.5% GEL. Excessive application of PEROCLIN 2.5% GEL may cause skin irritation and dryness. Therefore, use PEROCLIN 2.5% GEL only directed by your physician.

What precautions do I need to follow while using PEROCLIN 2.5% GEL?

Use PEROCLIN 2.5% GEL as directed by the physician. Avoid using PEROCLIN 2.5% GEL on inflamed, irritated, or sensitive skin areas. PEROCLIN 2.5% GEL may bleach your clothes, therefore avoid the contact of PEROCLIN 2.5% GEL with coloured fabrics. Before using PEROCLIN 2.5% GEL inform your doctor if you are pregnant or breastfeeding as a precaution. Contact your doctor if your skin condition worsens.

Can the use of PEROCLIN 2.5% GEL make my skin sensitive to sunlight?

Yes. PEROCLIN 2.5% GEL may make your skin more sensitive to sunlight. Therefore, use protective clothing while going outdoors. Do not exposure the affected part of the skin to the direct sunlight. Consult your doctor if you require any sunscreen to protect your skin while going outdoors. Consult your doctor if your skin condition worsens.

What are the common side effects of using PEROCLIN 2.5% GEL?

PEROCLIN 2.5% GEL may cause skin redness and peeling in some individuals during the first few weeks of therapy. If you experience this, stop using PEROCLIN 2.5% GEL for a short period until your skin recovers. However, consult your doctor immediately if your skin irritation becomes severe with redness, dryness, itching, stinging, or burning sensation.

Can PEROCLIN 2.5% GEL be used in children?

PEROCLIN 2.5% GEL is not recommended for use in children (aged below 12 years). It should be used in children and adolescents (aged 12 years or older) only if prescribed by the physician. Therefore, consult your doctor before using.

How does PEROCLIN 2.5% GEL works?

PEROCLIN 2.5% GEL acts by preventing the growth and multiplication of acne-causing bacteria. It can also open the skin pores and removes the accumulated dead skin cells and excess oil that triggers acne breakouts. Over time, it can also reduce oil production in the skin.

Can I use PEROCLIN 2.5% GEL to treat acne during pregnancy?

Currently, there are only limited data regarding the use of PEROCLIN 2.5% GEL in pregnant women. Therefore, consult your doctor before using PEROCLIN 2.5% GEL if you are pregnant or planning to become pregnant. Your doctor may prescribe you with PEROCLIN 2.5% GEL based on the risk and benefit ratio.

REFERENCES

1. KD. Tripathi. Macrolide, Lincosamide, Glycopeptide and Other Antibacterial Antibiotics; Urinary Antiseptics & Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 756 & 893.

2. Gregory T Warner 1, Greg L Plosker. Clindamycin/benzoyl peroxide gel: a review of its use in the management of acne. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. 2002. [Accessed 6th April 2022] https://pubmed.ncbi.nlm.nih.gov/12069641/

3. Jadran-Galenski Laboratorij d.d; Electronic Medicines Compendium (EMC) [Revised in November 2020] [Accessed 6th April 2022] https://www.medicines.org.uk/emc/files/pil.12604.pdf

4. Bausch Health Companies Inc., [Revised on Sep 2020] [Accessed 06 Apr 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=edae294f-cc8b-4f94-8d90-4c764fda307b

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    25 g
    Ingredient
    BENZOYL PEROXIDE 2.5 % w/w+CLINDAMYCIN 1 %W/W
    Hsn Code
    30049099
ALTERNATE BRANDS
Peroclin 5% Gel 15gm
Prescription Acne Rx required
Rs.520.00
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Peroclin 2.5% Gel 15gm

Peroclin 2.5% Gel 15gm Mkt: Ajanta Pharma Ltd

M.R.P.: Rs.441.00
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