Perinorm Injection 2ml

Vomitting/Emesis Rx required

MRP  ₹ 5.22
(Inclusive of all taxes) * Mkt: Ipca Laboratories Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

PERINORM INJECTION contains Metoclopramide which belongs to the group of medicines called Anti-emetics. It is indicated for both adults and children (aged 1 to 18 years) to prevent nausea and vomiting which may occur after surgery, chemotherapy or radiotherapy. It can also be used to treat nausea and vomiting which is associated with migraine in adults.

Migraine is a headache which causes severe throbbing pain or pulsing sensation particularly on one side of the head and it is characterized by symptoms such as nausea, vomiting and sensitivity to light.   

Your doctor may perform blood tests during treatment with PERINORM INJECTION to monitor your blood pigment (haemoglobin) levels. Your doctor may immediately or permanently stop your treatment if there are any abnormalities in the levels of blood pigment.

Before receiving PERINORM INJECTION, inform your doctor if you are having liver, kidney or heart diseases, porphyria (rare blood disorder), brain problems and also if you are using any other medicines that may affect your heartbeat.

PERINORM INJECTION is not recommended for use in patients with epilepsy, parkinson’s disease, bleeding, obstruction or tear in stomach or gut, tumour of adrenal gland (pheochromocytoma) and involuntary muscle spasms or if you are taking a medicine used to treat parkinson’s diseases (levodopa).

PERINORM INJECTION is not recommend for use during the first 3 months of pregnancy and it should be used with caution during pregnancy only if clearly advised by the doctor. It is not recommended for use in breastfeeding women as it may pass through the breast milk.

PERINORM INJECTION is not recommended for use in children (below 1 year of age) and should be cautiously used among elderly patients, hence consult your doctor before receiving it. The most common side effects of receiving PERINORM INJECTION are drowsiness, uncontrollable body movements, diarrhoea, restlessness and feeling weak. Inform your physician immediately if any of the side effect worsens.  

USES OF PERINORM INJECTION

  • Prevents nausea and vomiting (that occurs after surgery in adults and children)
  • Prevents delayed nausea and vomiting (that occurs after chemotherapy (in children) or caused by radiotherapy (in adults))
  • Treats nausea and vomiting caused due to migraine (in adults)

HOW PERINORM INJECTION WORKS

PERINORM INJECTION acts and supresses certain centres called dopamine (brain chemical) centres by decreasing the sensitivity of the nerves that transmit signals from gastrointestinal tract to the vomiting centres in the brain. It also relaxes the muscles of stomach and enhances the motility of gut and prevents nausea and vomiting.

DIRECTIONS FOR USE

PERINORM INJECTION will be given to you only by a doctor or a nurse into a vein as a slow injection (at least 3 minutes) or can be given as an injection into the muscle (intramuscularly). Your doctor will determine the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF PERINORM INJECTION

COMMON

  • drowsiness
  • uncontrollable movements of the body (such as shaking, tics, twisting movements or muscle stiffness or rigidity)
  • rigidity and tremor (similar to parkinson’s disease)
  • restlessness
  • diarrhoea
  • feeling weak
  • reduced blood pressure

UNCOMMON

  • elevated levels of hormone called prolactin (which cause milk secretion in men and women who are not breastfeeding)
  • irregular periods
  • hallucinations
  • decreased consciousness
  • slow heartbeat
  • allergy
  • visual problems and involuntary upward deviation of the eyeball

RARE

  • confusion
  • convulsions (fits) especially in patients with a history of epilepsy (seizures)

Inform your doctor if you experience any of the following side effects after receiving PERINORM INJECTION:

  • uncontrollable movements (often head or neck) which may occur in children or young adults
  • signs of a brain disorder called neuroleptic malignant syndrome (such as high fever, high blood pressure, convulsions (fits), sweating and production of saliva)
  • signs of severe allergic reactions (such as itching

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink lot of fluids such as water or fruit juice to keep yourself hydrated. Avoid eating high-fat or spicy foods. Inform your doctor if the symptom does not improve.

Feeling weak:

Drink plenty of fluids and eat a balanced diet and frequent meals. Follow a regular sleep schedule. Inform your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

PREGNANCY

PERINORM INJECTION is not recommended for use during the first 3 months of pregnancy. It should be used with caution during pregnancy only if considered clearly necessary. Consult your doctor before receiving PERINORM INJECTION.

BREASTFEEDING

PERINORM INJECTION is not recommended for use in breastfeeding women as it may pass through the breast milk and affect your baby. Consult your doctor before receiving PERINORM INJECTION.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy, drowsy or have uncontrollable twitching, jerking or writhing movements, unusual muscle tone leading to distortion of the body or vision problems after receiving PERINORM INJECTION.  

ALCOHOL

Avoid consumption of alcohol while receiving PERINORM INJECTION because it may increase the sedative effects.

KIDNEY

PERINORM INJECTION should be used with caution in patients having kidney problems. Your doctor may reduce the dose in patients with moderate or severe kidney problems. Consult with your doctor before receiving PERINORM INJECTION.

LIVER

PERINORM INJECTION should be used with caution in patients having liver problems. Your doctor may reduce the dose in patients with severe liver problems. Consult with your doctor before receiving PERINORM INJECTION.

ALLERGY

Tell your doctor before receiving PERINORM INJECTION if you are allergic to Metoclopramide or any of its constituents.

HEART DISEASE

PERINORM INJECTION should be used with caution in patients having heart diseases such as history of abnormal heartbeat (QT interval prolongation) or any other heart problems. Consult with your doctor before receiving PERINORM INJECTION.

OTHERS

PERINORM INJECTION is not recommended for use if you:

  • have bleeding, obstruction or a tear in your stomach or gut
  • have pheochromocytoma (rare tumour of adrenal gland)
  • have involuntary muscle spasms (due to other medicines)
  • have epilepsy (seizures or fits)
  • have parkinson’s disease (brain disorder causing uncontrollable movements of the body)
  • had gastrointestinal surgery (such as pyroplasty) in the last 3 to 4 days
  • have abnormal levels of blood pigments (methemoglobinemia or NADH cytochrome b5 deficiency

Before receiving PERINORM INJECTION, inform your doctor if you:

  • have problem with the levels of salts in the blood (such as potassium, sodium or magnesium)
  • have any brain problems
  • are suffering from porphyria (rare inherited blood disorder)

Use in paediatrics:

PERINORM INJECTION is not recommended for use in children (below 1 year of age) because of the increased risk of uncontrollable movements. It should be used with caution in children and adolescents aged between (1 to 18 years of age). Your child’s doctor may adjust the dose depending upon child’s age and body weight. Consult your child’s doctor for advice.  

Use in geriatrics:

PERINORM INJECTION should be used with caution in elderly patients. Your doctor might adjust your dose depending upon kidney or liver problems and overall health condition. Consult your doctor before receiving PERINORM INJECTION.

INTERACTIONS

A. Drug - Drug interactions:

Before receiving PERINORM INJECTION, inform your doctor if you have received or taking any of the following medicines:

  • medicines used to treat a brain disorder called parkinson’s disease (Ex. levodopa, carbidopa)
  • anticholinergics (medicines used to treat stomach cramps and spasms) Ex. dicyclomine, hyoscyamine
  • morphine derivatives (medicine used to treat severe pain) Ex. oxycodone, oxymorphone
  • sedative medicines (used to treat sleeping disorders, anxiety, panic attacks) Ex. diazepam, lorazepam
  • medicines used to treat mental health problems (Ex. quetiapine, risperidone), medicines used to treat depression (Ex. fluoxetine and paroxetine), neuroleptics (used to treat psychiatric disorders or nausea and vomiting) Ex. chlorpromazine
  • medicine used to treat heart failure (Ex. digoxin)
  • ciclosporin (used to treat immune problems)
  • mivacurium and suxamethonium (medicines used to relax the muscles)
  • atovaquone (used to treat pneumonia)
  • medicines used to treat pain (Ex. aspirin, paracetamol)

Overdosage:

PERINORM INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, inform your doctor if you experience any unusual symptoms such as uncontrollable movements, feeling drowsy, reduced level of consciousness, confusion, hallucinations and cardio-respiratory arrest (loss of function of heart and breathing).

SYNOPSIS

Drug :   Metoclopramide
Pharmacological Category :   Anti-emetics
Therapeutic Indication :   Nausea and Vomiting        
Dosage Forms :   Tablet, Capsule, Syrup, Injection

MORE INFORMATION

  • Store at room temperature

FAQs ABOUT PERINORM INJECTION

What are the common side effects of [GBNKWYWORD]?

The common side effects of receiving PERINORM INJECTION are drowsiness, uncontrollable body movements (such as shaking, tics, twisting movements or muscle stiffness or rigidity), tremors and rigidity similar to parkinson’s disease, restlessness, diarrhoea and feeling weak. Informs your doctor immediately if you experience any of these side effects.

How PERINORM INJECTION is administered?

PERINORM INJECTION will be given to you only by a doctor or a nurse into a vein as a slow injection (at least 3 minutes) or can be given as an injection into the muscle (intramuscularly). Your doctor will determine the correct dose and duration for you depending upon your age, body weight and disease condition.

What is PERINORM INJECTION and why is it given?

PERINORM INJECTION contains metoclopramide which belongs to the group of medicines called Anti-emetics. It is indicated for both adults and children (aged 1 to 18 years) to prevent nausea and vomiting which may occur after surgery, chemotherapy or radiotherapy. It can also be used to treat nausea and vomiting which is associated with migraine in adults.  

How long does it take for PERINORM INJECTION to act?

When PERINORM INJECTION is given intravenously, it starts acting within 1 to 3 minutes and if given intramuscularly (into a muscle) it may take up to 10 to 15 minutes. This effect lasts only for 1 to 2 hours. However, this may vary from person to person depending upon the condition. Ask for your doctor’s advice depending upon your specific condition.

Does PERINORM INJECTION increases blood pressure?

PERINORM INJECTION releases catecholamines which is a nerve chemical thought to increase the risk of high blood pressure. It must be used with caution in patients with pre-existing hypertension to prevent the risk of any unusual or serious problems. Ask for your doctor’s advice before receiving PERINORM INJECTION.

Is PERINORM INJECTION safe to use during pregnancy?

PERINORM INJECTION is not recommended for use during the first 3 months of pregnancy. It should be used with caution during pregnancy only if clearly advised by your doctor. Consult your doctor before receiving PERINORM INJECTION if you are pregnant or planning to get pregnant.

REFERENCES

1. KD Tripathi. Antiemetic, Prokinetic and Digestant Drugs. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page – 713.

2. Keith Kleinman. Metoclopramide. Science Direct. 2021. [Accessed on 3rd August 2022] https://www.sciencedirect.com/topics/medicine-and-dentistry/metoclopramide

3. Sasank Isola, Azhar Hussain, Anterpreet Dua, Karampal Singh and Ninos Adams. Metoclopramide. NIH. National Library of Medicine, National center for biotechnology information. April 2022. [Accessed on 3rd August 2022]   https://www.ncbi.nlm.nih.gov/books/NBK519517/

4. Cox, R., Newman, C.E. and Leyland, M.J. Metoclopramide in the reduction of nausea and vomiting associated with combined chemotherapy. Springer Link. April 1982. [Accessed on 3rd August 2022] https://link.springer.com/article/10.1007/BF00292884#citeas

5. Siegfried Hameln GmbH. Electronic Medicines Compendium (EMC); [Revised in November 2021] [Accessed on August 3rd 2022] 

https://www.medicines.org.uk/emc/files/pil.6283.pdf

6. Sandoz Canada Inc. Metoclopramide Hydrochloride Injection. [Revised in November 2014] [Accessed on August 3rd 2022] https://www.sandoz.ca/sites/www.sandoz.ca/files/Metoclopramide%20HCl%20PMe%2020141118.pdf

7. Pfizer Inc. Metoclopramide injection. [Revised in April 2022]. [Accessed on 3rd August 2022] https://labeling.pfizer.com/ShowLabeling.aspx?id=12225

USEFUL DIAGNOSTIC TESTS

  • Complete blood count

PRODUCT DETAILS

    Net Qty
    1 N
    Shelf Life
    24 months
    Item Weight
    15 g
    Ingredient
    Metoclopramide Hydrochloride 5 MG
    Hsn Code
    30049035
ALTERNATE BRANDS
Maxeron 5mg Injection 10ml
Prescription Vomitting/Emesis Rx required
Out of stock
Rs.14.57
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Perinorm Injection 2ml

Perinorm Injection 2ml Mkt: Ipca Laboratories Ltd

M.R.P.: Rs.5.80
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