INTRODUCTION
PENTATE IT CAPSULE is a combination of Itopride and Pantoprazole which belongs to the group of medicines called Gastrokinetic agent and Proton pump inhibitors. It is used in the treatment of Gastroesophageal Reflux Disease when monotherapy alone is not enough for some patients. PENTATE IT CAPSULE also treats Zollinger-Ellison syndrome and stomach and duodenal ulcers.
Along with PENTATE IT CAPSULE your doctor might want you to make some lifestyle changes such as having a balanced diet and exercising.
PENTATE IT CAPSULE is not recommended for use in patients having gastrointestinal haemorrhage, obstruction, or perforation. Consult your doctor before taking.
PENTATE IT CAPSULE should be used with caution in patients having severe liver disease, osteoporosis, cancer. PENTATE IT CAPSULE should be used with caution in pregnant women and is contraindicated in breastfeeding women. Consult your doctor before taking.
PENTATE IT CAPSULE is not recommended for use in children and adolescents below 12 years of age. Consult your doctor before taking.
The most common side effects of using PENTATE IT CAPSULE are headache, nausea, vomiting, flatulence, joint pain, diarrhoea and dizziness. Contact your doctor if any of these side effects worsen or doesn’t improve.
USES OF PENTATE IT CAPSULE
It is used to treat:
- gastroesophageal reflux disease
- stomach and duodenal ulcers
- Zollinger-Ellison syndrome
HOW PENTATE IT CAPSULE WORKS
PENTATE IT CAPSULE is a combination of Itopride and Pantoprazole where Itopride acts by increasing the movement (peristalsis) in the gastrointestinal tract and Pantoprazole works by stopping the production of acid by inhibiting certain enzymes (H+/K+ ATPase) at the surface of the cells present in the gastric lining.
DIRECTIONS FOR USE
Take this medicine as advised by your doctor. Swallow the medicine with a glass of water as a whole and do not crush or chew the medicine. Your doctor will prescribe the right dose depending on your age, body weight and disease condition.
SIDE EFFECTS OF PENTATE IT CAPSULE
COMMON
- headache
- nausea
- vomiting
- flatulence
- joint pain
- diarrhoea
- dizziness
HOW TO MANAGE SIDE EFFECTS
Nausea or Vomiting:
Take this medicine with, or just after meals. Stick to simple meals. Avoid eating rich or spicy food. Drink clear or ice-cold drinks, eat light, bland foods and avoid fried, oily, or sweet foods.
Headache:
Try to rest and relax. Do not involve yourself in rigorous activities. Apply a pain-relieving balm on your forehead.
Diarrhea:
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
WARNING & PRECAUTIONS
PREGNANCY
PENTATE IT CAPSULE should be used with caution in pregnant women. Consult your doctor before taking it.
BREASTFEEDING
PENTATE IT CAPSULE is not recommended for use in breastfeeding women. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or use machinery if you feel dizziness and disturbed vision after taking PENTATE IT CAPSULE.
LIVER
PENTATE IT CAPSULE should be taken with caution in patients having severe liver diseases. Consult your doctor before taking.
ALLERGY
Do not take PENTATE IT CAPSULE if you are allergic to Itopride, Pantoprazole or any other ingredients of this medicine.
OTHERS
PENTATE IT CAPSULE is not recommended for use if you:
- have gastrointestinal haemorrhage, obstruction or perforation
Use in pediatrics:
PENTATE IT CAPSULE is not recommended for use in children and adolescents below 12 years of age. Consult your doctor before taking.
Use in geriatrics:
Your doctor will decide the correct dose, duration depends on your age, body weight and health condition. Consult your doctor before taking PENTATE IT CAPSULE.
INTERACTIONS
A. Drug - Drug Interactions:
Before taking PENTATE IT CAPSULE, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, non-prescription or any herbal medicine.
Overdosage
If you or anyone else accidentally takes too much of PENTATE IT CAPSULE, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Itopride, Pantoprazole |
| Pharmacological Category | : | Prokinetic Drug, Proton Pump Inhibitor |
| Therapeutic Indication | : | Gastroesophageal Reflux Disease, Zollinger-Ellison syndrome and Stomach and Duodenal ulcers |
| Dosage Forms | : | Tablet, Capsule |
MORE INFORMATION
- Keep PENTATE IT CAPSULE out of reach of children
- Store below 25°C
FAQs ABOUT PENTATE IT CAPSULE
Is PENTATE IT CAPSULE safe to use during pregnancy and lactation?
PENTATE IT CAPSULE should be used with caution in pregnant women and is contraindicated in lactating mothers. Consult your doctor before taking PENTATE IT CAPSULE.
Can PENTATE IT CAPSULE cause nausea and vomiting?
Yes. Nausea and Vomiting are common side effects of PENTATE IT CAPSULE. To manage this, take this medicine with, or just after meals. Stick to simple meals. Avoid eating rich or spicy food. Drink clear or ice-cold drinks, eat light, bland foods and avoid fried, oily, or sweet foods.
Is PENTATE IT CAPSULE suitable for children?
PENTATE IT CAPSULE is not recommended for use in children and adolescents below 12 years of age. Contact your doctor before taking.
REFERENCES
1. KD. Tripathi. Antiemetic, Prokinetic and Digestant Drugs & Drugs for Peptic Ulcer and GERD. Essentials of medical pharmacology. Seventh edition. 2013. Page – 667 & 653.
2. Itopride. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Accessed on 28th May 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Itopride
3. Takeda GmbH. Electronic Medicines Compendium (EMC). [Revised in Feb 2020] [Accessed on 28th May 2022] https://www.medicines.org.uk/emc/files/pil.484.pdf
4. Leeford Healthcare. Pantafol – IT. [Accessed on 28th May 2022] https://www.leeford.in/product/24/pantafol-it
5. Tas Med (India) Pvt Ltd. Itorax – OD. [Accessed on 28th May 2022] https://tasmedlab.com/allproduct/itorax-range/#indications
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