INTRODUCTION

ORLEAN 60MG contain orlistat which belongs to a group of medicine called lipase inhibitors. It is used to treat obesity in conjunction with a low-calorie intake diet. Obesity is a disorder involving excessive body fat that increase the risk of health problem. It works in your digestive system to block about one-third of the fat in the food you eat from being digested. It attaches to the enzymes in your digestive system (lipases) and blocks them from breaking down some of the fat you have eaten during your meal. The undigested fat cannot be absorbed and is eliminated by your body.

Always take ORLEAN 60MG exactly as your doctor has told you. It can be taken immediately before, during a meal or up to one hour after a meal. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease or liver problems. Pregnant and breastfeeding women should consult the doctor before taking this medicine. It has no known effect on your ability to drive a car or operate machinery. This medicine is strictly not recommended for children and adolescents under 18 years. The most common side effects are headache, abdominal pain, flatulence (wind) with or without discharge, oily discharge, oily or fatty stools.

USES OF ORLEAN 60MG

• Treat obesity in conjunction with a low-calorie intake diet

HOW ORLEAN 60MG WORKS

ORLEAN 60MG blocks about one-third of the fat in the food you eat from being digested. It attaches to the enzymes in your digestive system (lipases) and blocks them from breaking down some of the fat you have eaten during your meal. The undigested fat cannot be absorbed and is eliminated by your body.

DIRECTIONS FOR USE

Always take ORLEAN 60MG exactly as your doctor has told you. It can be taken immediately before, during a meal or up to one hour after a meal. It should be taken with a well-balanced, calorie-controlled diet that is rich in fruit and vegetables and contains an average of 30% of the calories from fat.

Your daily intake of fat, carbohydrate and protein should be distributed over three meal. This mean you will usually take one capsule at breakfast time, one capsule at lunch time and one capsule at dinner time. You should avoid the intake of food containing fat between meals such as biscuits, chocolate, and savoury snacks.

SIDE EFFECTS OF ORLEAN 60MG

HOW TO MANAGE SIDE EFFECTS

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Abdominal pain:

Try to rest and relax. Eat and drink slowly and smaller and frequent meals. Applying a heat pad or covered hot water bottle on your stomach may also help. If still pain persists, speak to your doctor.

Bloating or wind:

Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If the symptom gets worse, contact your doctor straight away.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking,

• anticoagulant such as warfarin (used for thin blood)
• ciclosporin
• iodine salts and levothyroxine (used to treat thyroid gland problems)
• amiodarone (used to treat irregular heartbeat)
• medicines to treat HIV
• medicines for depression, psychiatric disorders, or anxiousness
• beta-carotene and vitamin E
• anticonvulsants medicines (used to treat convulsion)
• anti-diabetic medicine such as acarbose (used to treat type 2 diabetes mellitus)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ORLEAN 60MG

Can ORLEAN 60MG cause bloating?

Yes, this medicine may cause bloating in some individuals. Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If the symptom gets worse, contact your doctor straight away.

Can I take ORLEAN 60MG during liver disease?

It is not recommended in patients with active liver diseases(cholestasis). Before taking this medicine consult your doctor.

What is the use of ORLEAN 60MG?

It is used to treat obesity in conjunction with a low-calorie intake diet.

REFERENCES

1. KD Tripathi. Adrenergic System and Drugs. Essentials of Medical Pharmacology. Seventh Edition,2013. Page-139.

2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page -2889-2890.

3. Priya Sumithran 1, Joseph Proietto. Benefit-risk assessment of orlistat in the treatment of obesity. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. Aug 2014. [Accessed 04 Nov 2020] https://pubmed.ncbi.nlm.nih.gov/25064699/

4. Pharmaceutical Works POLPHARMA S.A; Electronic Medicines Compendium (EMC); [Revised on Aug 2016] [Accessed 04 Nov 2020] https://www.medicines.org.uk/emc/files/pil.8703.pdf

5. Pharmaceutical Works Polpharma S.A; Electronic Medicines Compendium (EMC); [Revised on Jul 2014] [Accessed 04 Nov 2020] https://webmedpharmacy.co.uk/media/pil/TEVA_Orlistat_120mg_Capsules_Hard_PIL_PL_00289_1680_July_2014.pdf

6. CHEPLAPHARM Arzneimittel GmbH. 29 July 1998; Electronic Medicines Compendium (EMC); [Revised on 17 June 2008] [Accessed 04 Nov 2020] https://www.ema.europa.eu/en/documents/product-information/xenical-epar-product-information_en.pdf

USEFUL DIAGNOSTIC TESTS

• Cholesterol - LDL