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OPTRA OZ Tablet 10's

OPTRA OZ Tablet 10's

Name: OPTRA OZ Tablet 10's
Brand: Reliance Formulation Pvt Ltd
SKU: 888882
Price: 85 INR

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Bacterial Infections Rx required

Ofloxacin 200 mg+Ornidazole 500 mg

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MRP ₹85.00

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*10 Tablet(s) in a Strip * Mkt: Reliance Formulation Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

INTRODUCTION

OPTRA OZ TABLET is a combination of Ornidazole and Ofloxacin which belongs to the group of medicines called Antibiotics. OPTRA OZ TABLET is used to treat various bacterial infections involving the blood (such as septicemia), brain (such as meningitis), lungs (such as pneumonia, bronchitis), ear and nose (such as sinusitis), urinary tract (such as cystitis), genital infections (including both the male and female genital organs), wound (post-operative infections), reproductive system (such as puerperal sepsis, septic abortion and endometritis) and stomach (such as peritonitis).

OPTRA OZ TABLET is also used as prophylaxis to prevent bacterial infections during surgical interventions (particularly involving the colon and in gynaecological operations).

Before initiating the treatment with OPTRA OZ TABLET, your doctor may recommend you to take relevant medical tests to understand your existing condition and to properly use this medicine.

Before taking OPTRA OZ TABLET inform your doctor if have heart disease (such as irregular heartbeat, valve disorder, poor heart function), kidney diseases (such as kidney failure or kidney injury), inflammation of the intestine, fits/seizure, autoimmune disease (such as multiple sclerosis), muscle-weakening diseases (such as myasthenia gravis), weak tendons (tendonitis, tendon rupture, rotator cuff), nerve pain (neuropathy), liver disease, psychiatric illness or emotional imbalances.

OPTRA OZ TABLET is not recommended for use in pregnant and breastfeeding women. OPTRA OZ TABLET is not recommended for use in children and adolescents (under 18 years of age) and it should be used with caution in elderly patients.

The common side effects of taking OPTRA OZ TABLET are nausea, vomiting, diarrhea, headache, itching and changes in taste sensation. Consult your doctor immediately if any of the side effects worsen during or after treatment with OPTRA OZ TABLET.

USES OF OPTRA OZ TABLET

To treat bacterial infections such as:

lungs infections (Ex. pneumonia, bronchitis)
sinus infections
urinary tract infections
meningitis
septicemia
puerperal sepsis, septic abortion and endometritis
peritonitis
post-operative wound infections
gonorrhoea and some other genital infections (both the male and female genital organs)
prophylaxis during surgical interventions (particularly involving the colon and in gynaecological operations)

HOW OPTRA OZ TABLET WORKS

OPTRA OZ TABLET is a combination of Ornidazole and Ofloxacin where Ornidazole kills parasites and bacteria that live in the absence of oxygen by generating harmful molecule which damages the DNA of the parasites and bacteria and ofloxacin is a quinolone antibiotic that kills bacteria by inhibiting the synthesis of bacterial DNA, hence helps to treat various infections.

DIRECTIONS FOR USE

Take OPTRA OZ TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose, duration and frequency of OPTRA OZ TABLET for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF OPTRA OZ TABLET

COMMON

headache, dizziness
nausea, vomiting
diarrhea
itching
sleep problems
external genital itching in women
vaginal inflammation
changes in taste sensation

UNCOMMON

stomach pain or discomfort
dry mouth
loss of appetite
fungal infection
agitation, restlessness
burning or irritation of the eye
cough and inflamed sore nose or throat
spinning sensation of the head (vertigo)

RARE

fast heartbeat
drowsiness
confusion, nightmare
decrease in blood sugar levels
depression or hallucination (feeling or hearing things not there)
changes in sensation of smell
shortness of breath or wheezing
excessive sweating
feeling faint, lightheadedness due to low blood pressure
hives
rash with pimples
pain or swelling around joints (tendonitis)
excessive sweating, hot flushes

Stop taking OPTRA OZ TABLET and contact your doctor immediately if you experience any of the following side effects:

severe allergic reactions (such as skin rash, itching, swelling of the face, lips, tongue and other parts of the body, difficulty in breathing or wheezing, blisters on the skin, sore throat, fever, headache)
painful skin rashes with blisters and peeling or scaling of the skin in conditions such as steven-johnson syndrome and toxic epidural necrolysis
abnormal heartbeat
changes in behavior, psychosis, depression, hallucination, disorientation or fainting
impaired vision or hearing
severe fever, body chills or muscle pain
swelling or rupture of tendons
numbness or tingling sensation of the skin
abnormal bleeding
abnormal body movements like fits or seizure
severe loose stools or diarrhea
difficulty in passing urine or urine discoloration
loss of consciousness
abnormal body sugar level
pain, burning, numbness and/or weakness especially in the feet and legs or hands and arms which indicates nerve damage
stomach pain, itching, dark urine or yellowish discoloration of the skin and in the white part of the eye (jaundice)

HOW TO MANAGE SIDE EFFECTS

Diarrhea

Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.

Dry Mouth

Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.

Headache

OPTRA OZ TABLET is not recommended for use in children and adolescents under 18 years of age. Consult your child’s doctor for advice.

USE IN GERIATRICS

Use with Caution

OPTRA OZ TABLET should be used with caution in elderly patients. Your doctor will decide the dose, duration and frequency of OPTRA OZ TABLET depending on the severity of your existing condition and other comorbidity conditions.

OTHERS

OPTRA OZ TABLET is not recommended for use if you:

have epilepsy or at risk of fits
have any pre-exisiting central nervous system (CNS) disorders
have history of inflammation and swelling of the tendons (tendonitis) especially after the treatment with quinolone antibiotics such as ciprofloxacin, norfloxacin or nadifloxacin
are suffering from or have a family history of glucose-6-phosphate dehydrogenase deficiency (an inherited disorder that affects the red blood cells)

Before taking OPTRA OZ TABLET, inform your physician if you:

have an enlargement or bulge of a large blood vessel (aortic aneurysm or large vessel peripheral aneurysm)
experienced a previous episode of aortic dissection (a tear in the aorta wall)
have a family history of aortic aneurysm or aortic dissection
have other risk factors or predisposing conditions (Ex. connective tissue disorders such as marfan syndrome or ehlers- danlos syndrome, turner syndrome, sjogren’s syndrome (an inflammatory autoimmune disease)
have vascular disorders such as takayasu arteritis, giant cell arteritis, behcet’s disease and high blood pressure or atherosclerosis, rheumatoid arthritis
have or ever had a history of mental illness
have salt imbalance in the blood (especially low level of potassium or magnesium in the blood)
illness of the nervous system called myasthenia gravis (muscle weakness)
are diabetic or suffer from low blood sugar
have due to urine tests for porphyrin (a pigment in the blood) or for opiates (strong painkillers)

INTERACTIONS

A. Drug-Drug interactions:

Before taking OPTRA OZ TABLET, inform your doctor if you are taking any of the following medicines:

antipsychotics such as olanzapine, clozapine (used to treat psychosis)
cyclosporin (used to prevent organ rejection after transplant)
quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide, pentoxifylline (used to treat irregular heart rhythm)
lithium or tricyclic antidepressants such as clomipramine, amitriptyline (used to treat depression)
macrolides such as erythromycin, clarithromycin, azithromycin (used to treat bacterial infection)
vecuronium bromide (used to relax muscles)
phenytoin, phenobarbital (used to treat epilepsy)
didanosine (used in the treatment of HIV infection)
furosemide (used to treat body fluid retention)
sucralfate, cimetidine (used to treat stomach ulcer)
antacids containing magnesium or aluminium (used for indigestion)
corticosteroids such as prednisolone, dexamethasone (used to treat inflammation)
non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or diclofenac (used to pain and inflammation)
theophylline (used to treat asthma)
insulin, glibenclamide (used to treat diabetes)
probenecid (used to treat gout)
methotrexate (used for rheumatism)
warfarin, acenocoumarin, phenprocoumon (used to treat or prevent blood clot)
medicines or dietary supplements that contain iron (for anemia) or zinc
herbal medicines

Overdosage:

If you or anyone else accidentally takes too much of OPTRA OZ TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of OPTRA OZ TABLET include confusion, dizziness, loss of consciousness, seizure or fit and nausea.

SYNOPSIS

Drug	:	Ornidazole and Ofloxacin
Pharmacological Category	:	Nitroimidazole and Fluoroquinolones
Therapeutic Indication	:	Various bacterial infections
Dosage Forms	:	Tablet, Capsule, Infusion, Injection, Syrup, Oral Suspension

MORE INFORMATION

Keep OPTRA OZ TABLET out of reach from children
Store OPTRA OZ TABLET at room temperature

FAQs ABOUT OPTRA OZ TABLET

Q: Can [GBBNKEYWORD] be used by pregnant women?

A: OPTRA OZ TABLET is not recommended for use in pregnant women. However, consult your doctor for advice before taking OPTRA OZ TABLET, as your doctor may outweigh the risks and benefits during life-threatening situations for use.

Q: Does OPTRA OZ TABLET cause diarrhea?

A: Yes, OPTRA OZ TABLET may cause side effects like diarrhea. Drink lot of fluids such as water or fruit juice to keep yourself hydrated. Avoid taking any medicine on your own to treat diarrhea. Consult your doctor immediately if the symptoms worsen or persists during treatment with OPTRA OZ TABLET.

Q: Can OPTRA OZ TABLET cause tendon weakness?

A: OPTRA OZ TABLET can increase the risk of tendon weakness or rupture. Stop taking OPTRA OZ TABLET and consult your doctor immediately if you experience symptoms like tendon pain in joints, swelling, hearing or feeling a snap or pop in a tendon area, bruising right after an injury in a tendon area, unable to move the affected area or bear weight, etc.

Q: Is OPTRA OZ TABLET safe to use in patients with heart problems?

A: OPTRA OZ TABLET should be used with caution if you have heart disease such as irregular heartbeat, poor functioning of the heart, heart attack, poor blood supply to the heart. Your doctor will study your existing heart condition and recommend relevant tests to outweigh the benefits to risks before suggesting you OPTRA OZ TABLET. If you experience any symptoms such as abnormal heartbeat, sweating, severe loose stools and dizziness after taking OPTRA OZ TABLET consult your doctor immediately. Also, inform your doctor of the medications you are taking to treat your heart or other conditions.

Q: Is OPTRA OZ TABLET safe for use in diabetic patients?

A: OPTRA OZ TABLET should be used with caution if you are having diabetes as this medicine may alter your body’s sugar level. Your doctor may suggest monitoring your body sugar level periodically. Consult your doctor for advice during treatment with OPTRA OZ TABLET.

REFERENCES

1. KD. Tripathi. Antimicrobial drugs, antiamoebic and other antiprotozoal drugs. Essentials of medical pharmacology. 8th Edition. 2019. Page – 763 & 897.

2. A. Soni, M. Chaudhary, A. Tamta, R. Sehgal, S.M. Shrivastava and V.K. Dwivedi. Science Alert. Therapeutic Efficacy of Ofloxacin and Ornidazole vs Mebatic: Toxicity Profile and Antioxidant Defense Study. [Revised in 2009] [Accessed on 3rd May 2022] https://scialert.net/fulltext/?doi=jp.2009.79.86

3. David G. Bailey, George Dresser and J. Malcolm O. Arnold, MB. National Library of Medicine (NIH). Grapefruit–medication interactions: Forbidden fruit or avoidable consequences. [Revised in 18th October 2018] [Accessed on 3rd May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589309/

4. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG). National Library of Medicine (NIH). Using medication: Using antibiotics correctly and avoiding resistance. [Revised in 13th December 2013] [Accessed on 3rd May 2022] https://www.ncbi.nlm.nih.gov/books/NBK361005

5. Teva Pharma (New Zealand) Limited, Inc. Medsafe. Ornidazole 500 mg, film coated tablet. [Revised in 18th October 2018] [Accessed on 3rd May 2022] https://www.medsafe.govt.nz/profs/Datasheet/a/arrowornidazoletab.pdf

6. Gerard Laboratories. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 3rd May 2022] https://www.medicines.org.uk/emc/files/pil.8481.pdf

7. Dr Reddy's Laboratories Limited. Ofloxacin tablet. DailyMed; National Library of Medicine; National Institute of Health. [Revised in December 2018] [Accessed on 3rd May 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=1d19a6db-6da5-e7de-f929-2d18bdfa2cf5&type=display#war

USEFUL DIAGNOSTIC TESTS

Complete blood count
Liver function test
Kidney function test
Bacterial Culture sensitivity test

AUTHOR DETAILS

Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 24 Feb 2023 | 09:49 AM(IST)

PRODUCT DETAILS

Net Qty

1 N

Shelf Life

720

Item Weight

17.5 g

Ingredient

Ofloxacin 200 mg+Ornidazole 500 mg

Hsn Code

30042034

Generic Name

Ofloxacin 200 mg+Ornidazole 500 mg

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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.