Best Price* ₹ 436.00 MRP ₹ 545.00
(Inclusive of all taxes) * Mkt: Overseas Pharma Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

Check Availability & Expiry

PINCODE:


INTRODUCTION

OPIZONE S INJECTION is a combination of Cefoperazone and Sulbactam which belongs to the group of medicines called Antibiotics. It is used to treat various bacterial infections such as respiratory tract infections, urinary tract infections (upper and lower), intra-abdominal infections, septicemia (serious bloodstream infection), meningitis (inflammation of brain and spinal cord membranes, typically caused by an infection), skin and soft tissue infections.

It is also used to treat bone and joint infections, gonorrhea (sexually transmitted bacterial infection), endometritis (inflammation of the uterine lining due to infection), pelvic inflammatory disease (infection of the female reproductive organs) and other infections of the genital tract.

Bacterial infections are caused by multiplication of specific harmful strain of bacteria anywhere in the body. It is characterized by symptoms such as fever, nausea, vomiting, headache tiredness and swollen lymph nodes in the neck, armpits, groin or elsewhere.

Before receiving OPIZONE S INJECTION, inform your doctor if you have impaired kidney function, severe biliary obstruction (blockage of the bile ducts), severe liver disease, malabsorption conditions and have schedule for laboratory tests (such as measuring glucose in the urine).

OPIZONE S INJECTION should be used with caution in pregnant and breastfeeding women only if advised by the doctor. Also, it should be used with caution in children and elderly patients.

The most common side effects of receiving OPIZONE S INJECTION are diarrhea, nausea and vomiting. Inform your doctor if any of these side effects bothers you.

USES OF OPIZONE S INJECTION

Treats bacterial infections such as:

  • respiratory tract infections
  • urinary tract infections (upper and lower)
  • intra-abdominal infections
  • septicemia
  • meningitis
  • skin and soft tissue infections
  • bone and joint infections
  • pelvic inflammatory disease
  • endometritis
  • gonorrhea
  • other infections of the genital tract

HOW OPIZONE S INJECTION WORKS

OPIZONE S INJECTION contains cefoperazone and sulbactam. Cefoperazone works by stopping the formation of bacterial cell coverings, which makes the bacteria susceptible for killing. Sulbactam works by reducing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, they helps to treat various bacterial infections.

DIRECTIONS FOR USE

OPIZONE S INJECTION will be given to you only by a doctor or a nurse, either into the vein (intravenously) or muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of the infection.

SIDE EFFECTS OF OPIZONE S INJECTION

COMMON

  • diarrhea
  • nausea, vomiting
  • coagulopathy (impairment in the blood's ability to clot)

UNCOMMON

  • headache
  • itching
  • raised red rashes (urticaria)
  • pain or inflammation of a vein at the site of injection
  • fever, chills

RARE

Inform your doctor immediately if you experience any of the following side effects after receiving OPIZONE S INJECTION:

  • allergic reactions
  • skin reactions such as toxic epidermal necrolysis, stevens-johnson syndrome, dermatitis exfoliative (signs include blistering and peeling of the skin)
  • persistent bleeding

HOW TO MANAGE SIDE EFFECTS

Nausea:

Take regular sips of cold drink. Stick to simple meals. Avoid eating oily, fried or spicy foods. Do not lie down or sleep immediately after eating. If nausea does not improve, inform your doctor.

Headache:

Apply hot or cold-water bag on your head. Drink plenty of fluids. Try taking rest in a quiet and dark room. Apply pain relieving balm on your forehead if necessary. Inform your doctor if the headache does not reduce.

Diarrhea:

Keep yourself hydrated by drinking lot of fluids such as water or fruit juices. If the symptom does not improve, inform your doctor.

WARNING & PRECAUTIONS

PREGNANCY

OPIZONE S INJECTION should be used during pregnancy only if considered clearly necessary Consult your doctor before receiving OPIZONE S INJECTION.

BREASTFEEDING

OPIZONE S INJECTION should be used with caution in breast-feeding women as small amount of this medicine is excreted in the breast milk. Consult your doctor before receiving OPIZONE S INJECTION.

DRIVING AND USING MACHINES

OPIZONE S INJECTION does not affect your ability to drive or use machinery.

ALCOHOL

Avoid consuming alcohol while receiving OPIZONE S INJECTION because it may cause flushing, sweating, headache and increase in the heartbeat.

KIDNEY

OPIZONE S INJECTION should be used with caution in patients with impaired kidney function. Consult your doctor before receiving OPIZONE S INJECTION.

LIVER

OPIZONE S INJECTION should be used with caution in patients with severe biliary obstruction (blockage of the bile ducts) and severe liver disease. Consult your doctor before receiving OPIZONE S INJECTION.

ALLERGY

Do not receive OPIZONE S INJECTION if you are allergic to cefoperazone, sulbactam, beta-lactam antibiotics (such as penicillins and cephalosporins (Ex. cefuroxime)) or any other ingredients of this medicine.

OTHERS

Before receiving OPIZONE S INJECTION, inform your doctor if you:

  • have poor diet and malabsorption conditions
  • have any scheduled laboratory tests (such as measuring glucose in the urine)

Use in pediatrics:

OPIZONE S INJECTION should be used with caution in children. Your child’s doctor may adjust the dose depending upon child’s body weight. Consult your child’s doctor for advice.

Use in geriatrics:

OPIZONE S INJECTION should be used with caution in elderly patients. Consult your doctor before receiving it.

INTERACTIONS

A. Drug-Drug interactions:

Before receiving OPIZONE S INJECTION, inform your doctor if you are taking any of the following medicines:

  • medicines used to treat bacterial infections such as aminoglycosides (Ex. gentamicin, tobramycin, amikacin and streptomycin)
  • oral anti-coagulants (Ex. warfarin) (used to prevent or treat blood clots)

Overdosage:

OPIZONE S INJECTION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor if you experience any unusual symptoms such as neurologic effects (such as fits).

SYNOPSIS

Drug :   Cefoperazone, Sulbactam
Pharmacological Category :   Cephalosporin; Beta-lactamase inhibitors
Therapeutic Indication :   Various bacterial infections
Dosage Forms :   Injection

MORE INFORMATION

  • Store below 25°C and protect from light

FAQs ABOUT OPIZONE S INJECTION

What is OPIZONE S INJECTION used for?

OPIZONE S INJECTION is a combination of Cefoperazone and Sulbactam which belongs to the group of medicines called antibiotics. It is used to treat several bacterial infections such as respiratory tract infections, urinary tract infections (upper and lower), intra-abdominal infections, septicemia, meningitis, skin and soft tissue infections, bone and joint infections, gonorrhea, endometritis, pelvic inflammatory disease and other infections of the genital tract.

How does OPIZONE S INJECTION work?

OPIZONE S INJECTION contains cefoperazone and sulbactam. Cefoperazone works by stopping the formation of bacterial cell coverings, which makes the bacteria susceptible for killing. Sulbactam works by reducing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, they helps to treat various bacterial infections.

How OPIZONE S INJECTION is administered?

OPIZONE S INJECTION will be given to you only by a doctor or a nurse, either into the vein (intravenously) or muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of the infection.

Is OPIZONE S INJECTION safe to use in patients with liver disease?

OPIZONE S INJECTION should be used with caution in patients with severe biliary obstruction (blockage of the bile ducts) and severe liver disease. Consult your doctor for advice before receiving OPIZONE S INJECTION.

What are the common side effects of OPIZONE S INJECTION?

The most common side effects of receiving OPIZONE S INJECTION are diarrhea, nausea, vomiting and coagulopathy (impairment in the blood's ability to clot). Inform your doctor if any of these side effects bothers you.

REFERENCES

1. Conan MacDougall. Penicillins, Cephalosporins and Other Beta-Lactam Antibiotics. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical, 2018. Page – 1023-1038.

2. Lan, Shao-Huan, Shen-Peng Chang, Chih-Cheng Lai, Li-Chin Lu and Hung-Jen Tang. Efficacy and safety of cefoperazone-sulbactam in empiric therapy for febrile neutropenia: A systemic review and meta-analysis. National Library of Medicine. February 2020. [Accessed on 4th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034635/

3. Chiang, Tsung-Ta, Hung-Jen Tang, Cheng-Hsun Chiu, Te-Li Chen, Mao-Wang Ho, Chen-Hsiang Lee, Wang-Huei Sheng and Ya-Sung Yang.Antimicrobial activities of cefoperazone-sulbactam in comparison to cefoperazone against clinical organisms from medical centers in Taiwan. Journal of Medical Sciences. December 2016. [Accessed on 4th June 2022] https://www.jmedscindmc.com/article.asp?issn=1011-4564;year=2016;volume=36;issue=6;spage=229;epage=233;aulast=Chiang;aid=JMedSci_2016_36_6_229_196365

4. Pfizer Limited. Electronic Medicines Compendium (EMC). [Revised in April 2020] [Accessed on 4th June 2022] https://labeling.pfizer.com/ShowLabeling.aspx?id=14800#:~:text=mEq)%20per%20gram.-,Sulbactam%20is%20an%20off%2Dwhite%20crystalline%20powder%20which%20is%20highly,(1.5%20mEq)%20per%20gram.

USEFUL DIAGNOSTIC TESTS

  • Complete Blood Count
  • Bacterial culture test

PRODUCT DETAILS

    Country Of Origin
    India
GET EXTRA DISCOUNT
Get upto 20%

Additional Discount on this product

Please get a call back from our expert

ALTERNATE BRANDS View All
PERAZONE S 1gm Injection 1's
Prescription Bacterial Infections Rx required
Rs.19.00
PERAZONE S 1.5gm Injection 1's
Prescription Bacterial Infections Rx required
Rs.27.90
HINEX Injection 1's
Prescription Infection Rx required
Rs.131.00
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

OPIZONE S Injection 1.5gm

OPIZONE S Injection 1.5gm Mkt: Overseas Pharma Pvt Ltd

M.R.P.: Rs.545.00
Copyright© 2022. All Rights Reserved.