Oliza Injection 1's

Schizophrenia Rx required

Best Price* ₹ 77.20 MRP ₹ 96.50
(Inclusive of all taxes) * Mkt: Intas Pharmaceuticals Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

OLIZA INJECTION contains Olanzapine which belongs to the group of medicines called Antipsychotics. It is used in the treatment and control of agitation, disturbed behavior in adult patients with schizophrenia. Schizophrenia is characterized by hearing, seeing or sensing things which are not there, mistaken beliefs, unusual suspiciousness, may also feel depressed, anxious.

Along with this treatment, your doctor might ask you to make certain lifestyle changes such as eating a healthy diet, regular exercise, quitting alcohol. Prior to the treatment, your doctor may want you to take several blood tests to understand your existing condition. Avoid consumption of alcohol during treatment with OLIZA INJECTION as it can make you feel drowsy.

OLIZA INJECTION is not recommended for use in patients previously diagnosed with eye problems like glaucoma. Before receiving OLIZA INJECTION, inform your doctor if you have a history of blood clotting, stroke, Parkinson’s disease, prostate, intestine, heart, liver or kidney disease, diabetes, and seizures.

OLIZA INJECTION should be used with caution among women who are pregnant. OLIZA INJECTION is not recommended for use in breastfeeding women and in children below 18 years of age. OLIZA INJECTION should be used with caution in elderly patients with dementia as it can cause death. Consult your doctor before receiving OLIZA INJECTION.

The most common side effects of receiving OLIZA INJECTION are changes in the levels of some blood cells, weight gain, sleepiness and feeling dizzy.

USES OF OLIZA INJECTION

  • For rapid control of agitation, disturbed behavior in patients with schizophrenia

HOW OLIZA INJECTION WORKS

OLIZA INJECTION exerts its action primarily on certain chemical messengers in the nervous system (dopamine and serotonin). It blocks the action of dopamine, allowing for normal dopamine neurotransmission, which leads to a decrease in positive symptoms in patients like hallucinations, delusions, and disorganized speech, thought, and behavior. It also blocks the action of serotonin helping in the decrease of negative symptoms like poor speech, being unable to express emotions, low motivation, and poor attention.

DIRECTIONS FOR USE

OLIZA INJECTION will be given to you only by a doctor or a nurse into the muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF OLIZA INJECTION

COMMON

  • weight gain
  • slower or faster heart rate, low blood pressure
  • sleepiness and pain at the site of injection
  • increases in levels of prolactin in the blood, changes in the levels of some blood cells, circulating fats and liver enzymes
  • feel dizzy (with a slow heart rate), especially while getting up from a lying or sitting position
  • increases in the level of sugars in the blood and urine and of uric acid and creatine phosphokinase in the blood
  • restlessness, tremor, unusual movements (dyskinesias)
  • constipation, dry mouth
  • rashes
  • loss of strength, extreme tiredness, feeling more hungry
  • water retention leading to swelling of the hands, ankles, or feet
  • fever, joint pain
  • sexual dysfunctions (decreased libido in males and females or erectile dysfunction in males)

UNCOMMON

  • hypersensitivity (swelling in the mouth and throat, itching, rash)
  • slow breathing, abnormal rhythms of heart
  • worsening of diabetes, at times associated with ketoacidosis (ketones in the blood, urine) or coma
  • seizures, muscle stiffness (even eye movements)
  • syndrome of restless legs, problems with speech (stuttering)
  • slow heart rate
  • sensitivity to sunlight
  • bleeding from the nose
  • abdominal distension
  • drooling
  • memory loss or forgetfulness
  • lack of ability to urinate
  • hair loss
  • absence or decrease in menstrual periods
  • changes in breasts in males and females like an abnormal production of breast milk or abnormal growth

RARE

  • lowering of normal body temperature
  • sudden unexplained death
  • inflammation of the pancreas with severe stomach pain and fever
  • liver disease(jaundice)
  • muscle disease presenting as aches and pains and painful erection

Stop receiving OLIZA INJECTION and contact your doctor immediately if you experience any of the following side effects:

  • unusual movement of face or tongue
  • blood clots in the veins especially in the legs (swelling, pain, and redness in the leg), which may travel through blood vessels to the lungs causing chest pain and difficulty in breathing
  • a combination of fever, faster breathing, sweating, muscle stiffness and drowsiness                                                                                                                                                                

HOW TO MANAGE SIDE EFFECTS

Dizziness:

Lie down until dizziness is resolved, then get up slowly. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol, and drugs. Consult your doctor if your symptom gets worse or persist.

Dry mouth:

Sip water regularly and other sugar free liquids. Do not use alcohol-containing mouthwashes because they can make your mouth dry, use the one that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if your symptom gets worse or persist.

Constipation:

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. Consult your doctor if your symptom gets worse or persist.

Stomach pain:

Try to rest and relax. Try to have smaller and more frequent meals and have them slowly. Keep a heat pad on your stomach. Consult your doctor if your symptom gets worse or persist.

WARNING & PRECAUTIONS

PREGNANCY

OLIZA INJECTION should be used with caution in pregnant women. Consult your doctor before receiving it.

BREASTFEEDING

OLIZA INJECTION is not recommended for use in breastfeeding women as it can pass through breast milk. Consult your doctor before receiving it.

DRIVING AND USING MACHINES

Do not drive and use machines after receiving OLIZA INJECTION, as it can make you feel drowsy.

ALCOHOL

Do not drink alcohol while receiving OLIZA INJECTION, as it can make you feel drowsy.

KIDNEY

OLIZA INJECTION should be used with caution in patients with kidney disease. Consult your doctor before receiving OLIZA INJECTION.

LIVER

OLIZA INJECTION should be used with caution in patients with liver disease. Consult your doctor before receiving OLIZA INJECTION.

ALLERGY

Inform your doctor before receiving OLIZA INJECTION if you are allergic to Olanzapine.

HEART DISEASE

OLIZA INJECTION should be used with caution in patients with heart disease, heart attack, sick sinus syndrome (abnormal heart rhythms), unstable angina or low blood pressure. Consult your doctor before receiving OLIZA INJECTION.

OTHERS

OLIZA INJECTION is not recommended for use if you:

  • have been previously diagnosed with eye problems such as certain kinds of glaucoma (increased pressure in eye)
  • have dementia (especially elderly patients)

Before receiving OLIZA INJECTION, inform your doctor if you:

  • you or your family has a history of blood clots or blood disorders
  • have stroke/mini stroke (temporary symptoms of stroke)
  • have Parkinson’s disease   
  • have prostate problems, blocked intestine (paralytic ileus)
  • have diabetes  
  • have seizures        
  • have salt depletion because of prolonged severe diarrhea and vomiting
  • are intolerant to some sugars

Use in pediatrics:

OLIZA INJECTION is not recommended for children under 18 years of age. Consult your doctor before receiving it.

Use in geriatrics:

OLIZA INJECTION should be used with caution in elderly patients. Especially in patients with dementia may suffer from stroke, pneumonia, urinary incontinence, tiredness, visual hallucinations, rise in body temperature, redness of the skin and trouble walking. Some fatal cases have been reported among the elderly. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Consult your doctor before receiving OLIZA INJECTION.

INTERACTIONS

A. Drug-Drug interactions:

Before receiving OLIZA INJECTION, inform your doctor if you are taking any of the following medicine:

  • diuretics (water tablets)
  • antidepressants or medicines for anxiety or to help you sleep (tranquillizers like benzodiazepines)
  • medicines for Parkinson’s disease (Ex. carbamazepine, fluvoxamine, or ciprofloxacin)

Overdosage:

OLIZA INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms like rapid beating of the heart, agitation, problems with speech, unusual movements (especially of the face or tongue), reduced level of consciousness, acute confusion, seizures, and coma, contact your doctor immediately.

SYNOPSIS

Drug :  

Olanzapine

Pharmacological Category :  

Antipsychotics

Therapeutic Indication :  

Treatment and control of agitation, disturbed behaviors in individuals with Schizophrenia

Dosage Forms :  

Injection

MORE INFORMATION

  • Keep OLIZA INJECTION out of reach from children
  • Do not store above 25°C

FAQs ABOUT OLIZA INJECTION

Is it safe to drink alcohol while taking OLIZA INJECTION?

Always avoid alcohol while receiving OLIZA INJECTION, it may cause drowsiness and worsen your condition.

What are the signs and symptoms of  OLIZA INJECTION overdose?

Overdosage of OLIZA INJECTION can cause rapid beating of the heart, aggressiveness, problems with speech, unusual movements (especially of the face or tongue) and reduced level of consciousness, acute confusion, seizures, coma, a combination of fever, faster breathing, sweating, muscle stiffness, and sleepiness, slower breathing, aspiration, high or low blood pressure and abnormal rhythms of the heart. 

Is OLIZA INJECTION a sleeping medicine?

No, OLIZA INJECTION is an antipsychotic used to treat schizophrenia which causes episodes of depression, mania, and other abnormal moods.

Can I receive OLIZA INJECTION during pregnancy?

OLIZA INJECTION should be avoided during pregnancy and should only be given if benefits outweigh the risk. Using it in last 3 months of pregnancy may cause unwanted symptoms in the unborn baby like shaking, muscle stiffness and/or weakness, sleepiness, agitation, breathing problems, and difficulty in feeding. Consult your doctor for advice.

REFERENCES

1. K D Tripathi. Drugs Used in Mental Illness: Antipsychotic and Antimanic Drugs. Essentials of Medical Pharmacology. 8th Edition. 2019. Page –469.

2. Kristina Thomas; Abdolreza Saadabadi. Olanzapine. [Revised on May 2022] [Accessed on 20th May 2022] https://www.ncbi.nlm.nih.gov/books/NBK532903/

3. Lilly S.A. Electronic Medicines Compendium (EMC). [Revised in September 2006] [Accessed on 20th May 2022] https://www.ema.europa.eu/en/documents/product-information/zyprexa-epar-product-information_en.pdf

4. Olanzapine. Mayoclinic. [Revised in January 2020] [Accessed on 20th May 2022] https://www.mayoclinic.org/diseases-conditions/schizophrenia/diagnosis-treatment/drc-20354449

5. Olanzapine. CDSCO. [Revised in August 2006] [Accessed on 20th May 2022] https://cdscoonline.gov.in/CDSCO/Drugs

USEFUL DIAGNOSTIC TESTS

  • MRI & CT scan
  • Blood tests

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    20 g
    Ingredient
    OLANZAPINE 10MG
    Hsn Code
    30049089
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Oliza Injection 1's

Oliza Injection 1's Mkt: Intas Pharmaceuticals Ltd

M.R.P.: Rs.96.50
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