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Drug Information

What is Olanzapine used for?

Olanzapine is used for the treatment of mental conditions, such as schizophrenia and bipolar disorder.

Olanzapine may also be prescribed for other conditions as determined by the doctor.

How does Olanzapine work?

Olanzapine belongs to the class of drugs called anti-psychotics. This drug acts by inhibiting certain receptors in the brain, which results in relieving positive and negative symptoms of schizophrenia.

How to take Olanzapine?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Olanzapine as prescribed by your doctor.

Swallow the tablet whole. Do not crush or chew the tablet. Take Olanzapine tablets with or without food.

If you miss a dose of Olanzapine, take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

The overdose symptoms of Olanzapine include the following:

  • Severe drowsiness
  • Irregular heartbeat
  • Seizures
  • Uncontrolled muscle movements
  • Confusion
  • Aggression

You must seek immediate medical care if you experience any of the above symptoms.

What are the drugs that interact with Olanzapine?

Drugs that interact with Olanzapine include the following:

  • Bupropion
  • Chlordiazepoxide
  • Clozapine
  • Fentanyl
  • Hydrocodone
  • Lorazepam
  • Metrizamide
  • Morphine
  • Naltrexone
  • Pentazocine
  • Topiramate
  • Tramadol
  • Zonisamide

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Olanzapine?

The following are the most common side effects of Olanzapine:

  • Dizziness
  • Drowsiness
  • Constipation
  • Weight gain
  • Increased appetite
  • Dry mouth

The following are the severe side effects and you may require immediate medical attention:

  • Diabetes
  • Decreased heartbeat
  • Mental/mood alterations
  • Yellow skin/eyes
  • Numbness in feet/arms
  • Abdominal pain
  • Trouble urinating
  • Difficulty in swallowing

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Olanzapine?

  • Avoid using the medicine if you are allergic to Olanzapine or similar drugs.
  • Avoid consumption of alcohol as it may worsen the side effects of Olanzapine.
  • Do not drive or operate heavy machinery if Olanzapine causes dizziness or blurred vision.
  • Avoid Olanzapine during breastfeeding because the safe use of the drug is not yet established.
  • Do not stop using the medication abruptly unless instructed by the doctor. Stopping the medication suddenly may cause the illness to return.
  • Be cautious while taking Olanzapine if you have stomach or intestinal diseases.
  • Keep the medication out of reach of children.

You are advised not to take Olanzapine if:

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Olanzapine?

  • Tell your doctor if you have any history of diabetes, seizures, liver problems, difficulty swallowing, difficulty breathing, dementia, seizures, heart disease or trouble breathing.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Notify your doctor if you are pregnant or breastfeeding.

Frequently asked questions about Olanzapine

  1. Do I need to be monitored for any laboratory parameters while taking Olanzapine?
  2. Yes, it is advised to monitor your blood glucose levels and complete blood picture regularly while taking Olanzapine medication.

  3. How should Olanzapine be stored?
  4. Olanzapine should be stored at room temperature (15 – 30O C). Protect from light, heat, and moisture.

  5. Can I take Olanzapine medication to treat dementia?
  6. No. Olanzapine is not prescribed to treat dementia. Please consult your doctor for appropriate medication in case of dementia.  

  7. What are the contraindications of Olanzapine?
  8. Olanzapine is contraindicated in patients with glaucoma.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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