Nodosis DS Tablet 15'S

Introduction About NODOSIS DS TABLET

Nodosis DS Tablet is a fast-acting alkalinizing formulation containing sodium bicarbonate, ideally used in conditions where the body produces too much acid or finds it difficult to eliminate it naturally. It is commonly advised to support metabolic balance, especially in individuals with high acid levels in the blood or urine. Whether recommended as part of a specialized plan for urine alkalinization or to support digestive comfort during bouts of heartburn or indigestion, this tablet provides versatile support under medical guidance.  

This tablet is ideally suited for patients with conditions associated with metabolic acidosis, excessive stomach acid, or those on medications that require urinary pH adjustment. Nodosis DS may also be used in critical care settings, including during cardiac support in specific acute cases under professional supervision. The medicine should be used exactly as directed, usually after meals, and swallowed whole with water. Dosage depends on the individual’s metabolic status and must be prescribed by a healthcare provider based on diagnostic assessments such as blood pH or electrolyte levels.

Patients should follow specific precautions while using Nodosis DS Tablet. Individuals with kidney or heart conditions, sodium-restricted diets, or those prone to electrolyte imbalances should discuss their full medical history before use. Regular monitoring may be advised for people with chronic health conditions or those taking medications like diuretics, corticosteroids, or certain antibiotics. Common side effects may include stomach cramps, gas, or nausea. Rarely, one may experience more serious reactions like swelling, shortness of breath, or muscle twitching, which require prompt medical attention.

For pregnant or breastfeeding women, the use of Nodosis DS should only occur if recommended by a doctor after evaluating potential risks and benefits. Excess sodium intake should be avoided unless clinically indicated, and healthcare providers may advise dose adjustments or periodic lab monitoring. Elderly patients and children should use this medicine strictly under medical supervision. For best results, always follow your doctor’s instructions closely, avoid self-adjusting doses, and seek timely guidance if discomfort arises.

Uses Of NODOSIS DS TABLET

• To manage metabolic acidosis
• Certain intoxications (Ex. methyl alcohol, phenobarbital, salicylates)
• Severe diarrhoea
• Haemolytic reactions requiring alkalinization of the urine
• As an adjunct in hyperkalemia
• In advanced cardiac life support (ACLS) during cardiopulmonary resuscitation (CPR)

Benefits of NODOSIS DS TABLET

Nodosis DS Tablet for Metabolic Acidosis

Nodosis DS Tablet is often prescribed for conditions where the body produces excess acid or is unable to remove it effectively, a state known as metabolic acidosis. It helps correct the acid-base imbalance by neutralizing the extra acid in the blood. By supporting normal pH levels, it allows vital organs and metabolic processes to function optimally. This tablet is typically recommended under medical supervision based on blood test results.

Nodosis DS for Urine Alkalinization

Nodosis DS can be used to increase urine pH, a process known as urine alkalinization. This helps in creating a less acidic environment in the urinary tract, which improves solubility of certain substances and supports kidney function. It is commonly advised in certain urinary conditions or during specific medication therapies that benefit from higher urine pH. Ensure it is taken as directed and keep hydration levels optimal.   

Nodosis DS for Heartburn or Indigestion

Nodosis DS Tablet may offer relief in cases of heartburn, sour stomach, or indigestion caused by excess stomach acid. By neutralizing gastric acid, it helps soothe discomfort caused by acidity. It is often recommended after meals for maximum benefit. Regular symptoms should be reported to a healthcare professional for proper evaluation.  

Nodosis DS for Cardiac Life Support

Nodosis DS (sodium bicarbonate) may be used in emergency settings as part of cardiac life support protocols. In specific conditions such as severe acid-base disturbances during resuscitation, it may be administered to balance blood pH levels. This usage is highly specialized and performed by medical professionals in critical care settings. It is not intended for home or routine use without medical supervision.

How NODOSIS DS TABLET Works

Mechanism of Action of Nodosis DS Tablet

Nodosis DS Tablet works by using sodium bicarbonate, an alkalizing agent, to balance excess acidity in the body. Once ingested, sodium bicarbonate reacts with acids in the stomach or bloodstream to form water and carbon dioxide, helping to neutralize high acid levels.

• Neutralizes acid: Sodium bicarbonate raises the pH level of acidic fluids, making them less acidic.
• Supports metabolic balance: It helps maintain a stable acid-base balance in the blood and tissues, especially when acid levels rise due to health conditions or diet.
• Promotes urinary alkalization: It increases the pH of urine, which can enhance the elimination of waste products and reduce irritation in the urinary tract.
• Fast-acting relief: Its action begins quickly and is often used to relieve acid build-up or discomfort.  

This mechanism makes Nodosis DS useful in conditions requiring acid-base correction, urinary pH management, or stomach acid neutralization, all while supporting the body’s natural balance.

How to use NODOSIS DS TABLET

How to Take Nodosis DS Tablet

• Follow your doctor’s instructions regarding dose and duration. Do not self-adjust the dosage.
• Take the tablet after meals to reduce the chance of stomach discomfort.
• Swallow the tablet whole with a glass of water. Do not crush or chew unless advised by your physician.
• Use at the same time daily to maintain consistent benefits and reduce the risk of missing a dose.
• Avoid taking it with acidic beverages like cola, citrus juices, or vinegar-based drinks as they can reduce its effectiveness.
• Do not exceed the recommended dose. High doses may cause excess sodium or electrolyte imbalance.
• If you are taking other medicines, especially antibiotics, diuretics, or antacids, check with your doctor to avoid interactions.
• Stay hydrated while using this medicine, especially if prescribed for urinary alkalization.
• Continue using it even if you feel better unless your doctor advises you to stop.

What if I forgot to take NODOSIS DS TABLET

• If you forget to take a dose of Nodosis DS Tablet, take it as soon as you remember.
• However, if it’s nearly time for your next dose, skip the missed dose and go back to your regular schedule.
• Do not take two doses at the same time to make up for the missed dose.
• Missing a dose occasionally is unlikely to cause problems but try to take the tablet consistently for best results.
• If you frequently forget doses, consider setting reminders or using a pill organizer.
• If you’re unsure about what to do, it's best to check with your doctor or pharmacist for guidance.

Overdose

Symptoms of an overdose of Nodosis DS Tablet may include severe muscle twitching, confusion, extreme irritability, frequent urination, and an unusually fast breathing rate. You may also experience swelling of the legs, persistent headaches, or irregular heartbeat. In severe cases, it may lead to seizures or loss of consciousness. If you suspect an overdose, seek immediate medical attention or visit the nearest hospital without delay.

Side Effects Of NODOSIS DS TABLET

Common side effects of Nodosis DS tablet:

• Gas and bloating
• Stomach cramps or pain
• Increased urination
• Nausea or vomiting
• Headache

When to Seek Medical Attention?

Stop taking Nodosis DS Tablet and contact your doctor immediately if you experience any of the following side effects:

• Severe stomach pain or persistent abdominal discomfort
• Vomiting or nausea that does not improve
• Muscle twitching, cramps, or unusual weakness
• Swelling in the legs, ankles, or sudden weight gain
• Shortness of breath, chest discomfort, or racing heartbeat
• Severe headache, confusion, or unusual tiredness
• Skin rash, itching, swelling of the face or throat
• Changes in urine output or difficulty urinating

How To Manage Side Effects

Warning & Precautions

Other Warnings for NODOSIS DS TABLET

Before taking Nodosis DS Tablet, inform your physician if you:

• Are on a sodium-restricted diet
• Have low calcium levels or conditions affecting electrolyte balance
• Are taking any other medications, including diuretics, corticosteroids, or antacids

Safety Advice

• Low Calcium Levels: Nodosis DS may worsen low calcium levels in the blood (hypocalcaemia). If you have conditions like hypoparathyroidism or vitamin D deficiency, make sure your doctor is aware before starting this medication.
• Special Dietary Restrictions: This medicine contains significant sodium, which may not be suitable for people on a salt-restricted diet. Individuals with kidney or heart issues should avoid additional hidden salt sources while using it.
• Gastrointestinal Disorders: If you have chronic digestive issues like colitis or severe constipation, using this medication may worsen discomfort or change bowel habits. Monitoring is recommended.
• Surgery: If you are scheduled for a surgery or procedure, inform your healthcare provider if you are taking Nodosis DS, as sudden shifts in acid-base balance may interfere with certain anaesthetic drugs.

Diet and Lifestyle Advice

• Stay Hydrated: Drink plenty of water throughout the day. Adequate fluid intake helps maintain a healthy electrolyte balance and supports kidney function, especially during alkalinization of urine.
• Balanced, Low-Acid Diet: Include alkaline-promoting foods like bananas, leafy vegetables, sweet potatoes, and coconut water. Limit acidic foods and beverages such as citrus fruits, tomatoes, vinegar, cola drinks, and processed foods, as they can counteract the benefits of the medication.
• Limit High-Sodium Foods: Nodosis DS contains sodium bicarbonate, which contributes to total sodium intake. Avoid salty snacks, canned foods, and processed meats to reduce the risk of fluid retention or increased blood pressure.
• Avoid Alcohol and Caffeine: These can irritate the stomach lining and may increase acid production, reducing the effectiveness of the medicine. Caffeine may also disturb electrolyte levels.
• Maintain a Healthy Weight: Excess weight puts pressure on the digestive system, potentially worsening acid-related conditions. Regular exercise (like walking, yoga, or swimming) can help.
• Avoid Eating Large Meals: Opt for smaller, frequent meals instead of heavy meals. Overeating can trigger acid imbalance and digestive discomfort.
• Monitor Urine Colour: Clear to light yellow urine is generally a sign of adequate hydration. Dark or strong-smelling urine may indicate dehydration or imbalance.
• Stress Management: Stress can affect digestion and acidity levels. Engage in relaxation techniques like deep breathing, meditation, or light stretching for better overall metabolic balance.

1. Nodosis DS Tablet vs Citravescent – Urinary Alkalinization

Feature	Nodosis DS Tablet	Citravescent
Active Ingredient	Sodium Bicarbonate	Sodium Citrate + Citric Acid
Pharmacological Action	Systemic alkalinizer, neutralizes excess acid	Converts into alkaline substances in the body
Primary Use	Supports management of metabolic acidosis and urinary alkalinization	Helps maintain alkaline urine, supports urinary comfort
Form	Tablet	Effervescent powder/sachet
Administration	Swallowed with water, usually after meals	Dissolved in water before consumption
Onset of Action	Quick and reliable acid neutralizing effect	Fast action due to effervescent nature
Sodium Content	Contains sodium – caution advised in heart or kidney conditions	Contains sodium & citrate – monitor salt intake
Taste/Palatability	Neutral taste, tablet-based	Citrus flavour, may be more palatable for some
Convenience	Portable, easy to carry	Requires water and mixing before use
Suitability	May be preferred for those who want fixed dosing and neutral taste	Suitable for users preferring flavoured alkaline drink
Use in Kidney Conditions	Can be used under medical supervision	Used under doctor’s advice, especially in urinary issues
Storage	Easy to store, no mixing needed	Requires dry storage to prevent clumping

2. Nodosis DS Tablet vs Alkasol Syrup – Acid Balance

Feature	Nodosis DS Tablet	Alkasol Oral Solution / Syrup
Active Ingredient	Sodium Bicarbonate	Disodium Hydrogen Citrate
Pharmacological Action	Acts as a systemic alkalizer; neutralizes excess acid	Citrate converts to bicarbonate in the body, raising systemic and urinary pH
Primary Use	Supports acid-base balance (e.g., metabolic acidosis)	Used to alkalize urine and manage conditions like kidney stones, gout, or acidic urine
Form	Tablet	Liquid (syrup / oral solution)
Administration Method	Swallowed with water	Diluted in water before taking; shake before use
Onset of Action	Rapid neutralization of acid	Moderate depends on metabolism of citrate to bicarbonate
Sodium Load	Contains sodium may require monitoring in sodium-sensitive conditions	Lower direct sodium, but metabolizes to bicarbonate; still needs monitoring in some conditions
Convenience	Easy to carry, fixed-dose tablet	Syrup form may be more suitable for patients who prefer liquids or have difficulty swallowing tablets
Taste / Palatability	Neutral, no strong flavour	More palatable; flavour and dilution may make it easier to take for some people
Use in Renal / Heart Conditions	Use under medical supervision due to sodium content	Also requires supervision; used in kidney-related acid balance conditions
Storage	Simple, dry storage	Liquid; needs to be kept tightly closed and stored as per label to avoid contamination or degradation

Drug - Drug interaction

1. Antifungal Medicines (e.g., Ketoconazole, Itraconazole)

Interaction: Nodosis DS can lower the acidity in the stomach, reducing the absorption of antifungal drugs that require acidic environments to work well.
Management: Maintain a gap of at least 2 hours between Nodosis DS and antifungal medication. Consult the doctor before starting or stopping any medicine.

2. Antibiotics (e.g., Tetracyclines, Ciprofloxacin)

Interaction: Sodium bicarbonate can reduce the absorption of certain antibiotics, making them less effective.
Management: Take these antibiotics at least 2–3 hours before or after Nodosis DS. Inform your doctor if you're on both medications.

3. Aspirin and Other Salicylates

Interaction: Nodosis DS may increase the excretion of salicylates, reducing their effectiveness.
Management: Doctors may adjust your dose or recommend an alternative. Avoid taking high doses of aspirin without medical guidance if also taking this tablet.

4. Heart Medicines (e.g., Quinidine)

Interaction: Sodium bicarbonate may increase the levels of certain heart medications, potentially affecting heart rhythm.
Management: Regular monitoring and dosage adjustments may be required. Inform your doctor if you’re experiencing chest discomfort or palpitations.

5. Diuretics (Water Pills)

Thiazide Diuretics: May cause low potassium when combined with sodium bicarbonate.

Potassium-Sparing Diuretics: May increase the risk of too much sodium or potassium in blood.

Management: Blood tests and renal function monitoring may be required. Your doctor may adjust your dose or suggest dietary changes.

6. Lithium

Interaction: Sodium bicarbonate can reduce lithium levels in the blood, reducing its effect.
Management: Dose adjustments and regular blood level monitoring are recommended. Do not alter any lithium dose without medical advice.

7. Corticosteroids (e.g., Prednisone)

Interaction: May increase sodium retention and fluid buildup when used with sodium bicarbonate.
Management: Ask your doctor if additional monitoring or dietary modifications are needed. Proper hydration and moderation of salt intake may be suggested.

8. Vitamin D or Calcium Supplements

Interaction: May increase the risk of kidney stones or high calcium levels.
Management: Take these supplements under guidance and follow your doctor’s dietary and medication advice. Regular health and lab check-ups may be recommended.

9. Methenamine (Urinary Antiseptic)

Interaction: The effect of methenamine may be reduced because it works better in acidic urine.
Management: Discuss alternatives or timing adjustments with your doctor. Do not take both without proper medical supervision.

Drug - Food interaction

1. High Sodium Foods

Interaction: Since Nodosis DS contains sodium, eating high-sodium foods like salted snacks, processed meats, pickles, or canned soups may increase total sodium levels in the body. This can affect blood pressure and water retention.
Management: Choose low-salt or no-added-salt foods. Monitor your salt intake, especially if you have kidney or heart conditions. Talk to your doctor or dietitian for personalized dietary advice.

2. Acidic Foods and Beverages

Interaction: Consuming acidic foods like citrus fruits (lemon, oranges), tomatoes, and vinegar-based products may increase acidity levels in the stomach. This could reduce the neutralizing effect of the tablet.
Management: Limit acidic foods and choose alkaline or neutral options like bananas, melons, and oats. Maintain balance as per your doctor's dietary guidance. Avoid consuming acidic drinks close to your medication dose.

3. Caffeine-Containing Beverages (Coffee, Tea, Energy Drinks)

Interaction: Caffeine can increase stomach acid secretion, which may counteract the effect of Nodosis DS in managing acidity.
Management: Moderate your caffeine intake and have these drinks in small quantities. Avoid taking them immediately before or after your dose. Discuss with your doctor if you’re a frequent caffeine user.

4. Milk and Dairy Products

Interaction: In some cases, combining dairy products with sodium bicarbonate may contribute to stomach discomfort or bloating.
Management: Take Nodosis DS Tablet at least 1–2 hours apart from heavy dairy intake if you notice discomfort. Monitor for bloating or gas and adjust timing under medical guidance.

5. High-Potassium Foods

Interaction: While Nodosis DS itself doesn’t add potassium, high-potassium foods (like bananas, avocados, spinach) could affect electrolyte balance if combined with other medicines or diets recommended for kidney issues.
Management: Your doctor may recommend a balanced potassium intake based on your health. Always follow dietary guidance suited for your condition.

6. Large, Heavy Meals

Interaction: Taking Nodosis DS immediately after a very heavy meal may cause bloating or excessive gas due to increased bicarbonate breakdown in the stomach.
Management: Opt for smaller, balanced meals and take the tablet after light to moderate meals unless otherwise advised. Track how meals affect your comfort and inform your doctor.

Synopsis

Drug	Sodium Bicarbonate
Pharmacological Category	Systemic alkalinizes, Antacid
Therapeutic Indication	Management of metabolic acidosis and support for urinary alkalinization
Dosage Forms	Tablet, Injection

More Information

FAQs About NODOSIS DS TABLET

Q: What is Nodosis DS Tablet used for?

A: Nodosis DS Tablet contains Sodium Bicarbonate, a compound that helps balance acid levels in the body. It is commonly used to manage conditions linked to high acidity. This tablet supports the body’s natural mechanisms by helping neutralize excess acid. It is often advised by doctors when the body’s acid levels need careful control. It can also be used in certain kidney-related conditions. Always take it as recommended by a healthcare provider.

Q: How should I take Nodosis DS Tablet?

A: This tablet should be taken exactly as prescribed by your doctor. It’s usually consumed with water and may be taken after meals to avoid stomach discomfort. Swallow the tablet whole do not crush or chew it unless directed. Timing and dose depend on your medical condition. Follow all dosing instructions carefully. Avoid self-adjusting the dose without medical advice.

Q: Can I take Nodosis DS Tablet on an empty stomach?

A: It’s generally advised to take Nodosis DS Tablet after meals to reduce the risk of stomach discomfort. Taking it on an empty stomach may increase the chances of bloating or gas. However, always follow your doctor’s instructions based on your condition. If you experience discomfort, talk to your healthcare provider. Do not alter how you take it without medical guidance. Keep track of any unusual symptoms.

Q: Can I take Nodosis DS Tablet daily?

A: Nodosis DS may be taken daily if your doctor has prescribed it that way. It depends on your condition and response to treatment. Some people may need it long-term under medical supervision. Always follow the prescribed dosage and schedule. Do not make changes without consulting your healthcare provider. Regular monitoring may be required if you’re taking it long-term.

Q: Are there any common side effects of Nodosis DS Tablet?

A: Some people may experience bloating, gas, or increased thirst. Mild stomach upset or nausea can also occur. High doses may cause increased sodium levels in the blood. If you experience swelling, headache, or confusion, seek medical help. Most side effects are temporary and mild. Always report persistent or worsening symptoms to your doctor.

Q: Is Nodosis DS Tablet habit-forming?

A: No, Nodosis DS Tablet is not known to be habit-forming. It is used to support internal balance and does not affect the brain or nervous system. You can stop using it once your doctor advises. Continue taking it only as long as medically necessary. Always complete the recommended course. Follow-up checks may be required if used for long periods.

Q: Can Nodosis DS Tablet be used for acidity?

A: Yes, it may be used to help control acidity by neutralizing stomach acid. It helps in managing discomfort related to acid imbalance. However, it should not be used casually like antacids without medical advice. Proper diagnosis is important in acid-related symptoms. Follow your doctor’s instructions for correct usage. Self-medication may not be safe in all cases.

Q: How long does it take for Nodosis DS to work?

A: The effects usually begin within a short time of consumption. It works by quickly neutralizing excess acid in the body. However, the time may vary depending on your condition. Give the medicine time to show its full effect. Consistency is important for best results. If you don’t notice improvement, talk to your healthcare provider.

Q: Can I take Nodosis DS Tablet with other medications?

A: Some drugs may interact with sodium bicarbonate, especially those affecting electrolyte balance. Always inform your doctor about all medicines you are taking. They may advise you on timing or dose adjustments. Avoid combining it with over-the-counter antacids without guidance. Certain antibiotics may also be affected. Always keep your healthcare provider informed.

Q: Does Nodosis DS Tablet affect blood pressure?

A: Since it contains sodium, it may raise blood pressure in some individuals. People with existing hypertension should use it cautiously. Regular monitoring is advised if you have heart or blood pressure issues. Always notify your doctor if you notice unusual swelling or headaches. They may adjust your dose or suggest alternatives. Follow medical advice strictly.

Q: What diet should I follow while taking Nodosis DS Tablet?

A: Follow a diet that’s low in sodium and balanced in minerals. Avoid excessive salt or processed foods. Stay well-hydrated unless otherwise advised. Your doctor may also guide you on limiting acidic foods. Regularly monitoring your diet helps improve its effectiveness. Always follow medical or dietary guidance.

Q: What happens if I take too much Nodosis DS Tablet?

A: Overdose may lead to symptoms like confusion, severe bloating, muscle twitching, or irregular heartbeat. Some people may experience breathing difficulties or swelling due to high sodium levels. Always seek immediate medical help if an overdose is suspected. Do not wait for symptoms to worsen. Keep out of children’s reach to prevent accidental use. Follow instructions carefully to avoid overdose.

Q: Does Nodosis DS Tablet work immediately for acidity?

A: It may provide quick relief in some cases as it neutralizes excess acid. However, the exact response depends on individual health and acidity level. It’s best used under medical advice rather than as an on-the-spot antacid. Give it time and take it as directed. If symptoms persist, consult your doctor. It’s intended for controlled relief in specific situations.

Q: Can Nodosis DS Tablet cause gas or bloating?

A: Yes, bloating and gas can occur as it releases carbon dioxide when neutralizing acid. These are generally mild and temporary. Taking the tablet after meals may reduce discomfort. If bloating is severe or persistent, inform your doctor. Adjustments in diet may also help reduce these effects. Do not stop the medicine without medical advice.

Q: Can I stop taking Nodosis DS once I feel better?

A: Always follow through the course as advised by your doctor. Stopping too early may disrupt acid balance again. Some conditions require a gradual reduction instead of sudden stopping. Talk to your healthcare provider before making changes. They may modify your dose based on progress. Never adjust dosage without guidance.

References

1.Steadfast Medishield.Nodosis DS tablet. [Accessed on 16th November 2025]

2. Niluk Leon Senewiratne; Allison Woodall; Ahmet S. Can. Nododsis (Sodium bicarbonate). NIH National Library of Medicine, National centre for biotechnology information. [Revised in 12th February 2024][Accessed on 16th November 2025]

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