INTRODUCTION

NICARDIA RETARD 20MG contains Nifedipine which belongs to a group of medicines called calcium antagonists. It is used to treat high blood pressure and to control angina (chest pain). It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard. It controls chest pain by increasing the supply of blood and oxygen to the heart.

Always take this medicine exactly as your doctor has directed you. Take this medicine with or without food. Swallow the medicine whole. Before using the medicine, tell your doctor know if you have any heart, liver, or kidney problems. Monitor your blood pressure regularly to make sure that this medicine is working properly. It is not suitable for use in children and adolescents below 18 years of age. Do not drive or handle any machines while taking this medicine. In addition to this medicine, lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes. The most common side effects are headache, nausea, vomiting, dizziness, flushing, etc.

USES OF NICARDIA RETARD 20MG

• High blood pressure
• Angina (chest pain)
• Raynaud’s phenomenon which causes discolouration (often whitening) of the fingers and toes

HOW NICARDIA RETARD 20MG WORKS

For high blood pressure: It works by relaxing and expanding the blood vessels. This makes the blood flow more easily and lowers blood pressure. Lower blood pressure reduces the strain on your heart.

For angina: It works by relaxing and expanding the arteries supplying the heart. This allows more blood and oxygen to reach the heart and decreases the strain on it.

For Raynaud’s phenomenon: It works by relaxing and expanding the blood vessels in the fingers and toes. This helps ensure a good blood supply.

DIRECTIONS FOR USE

Always take this medicine exactly as your doctor has directed you. Take this medicine with or without food. Swallow the medicine whole. Do not bite, chew or break them. Take your dose at the same time each day, preferably in the morning with a glass of water. Avoid taking with grapefruit juice. Do not stop taking this medicine without consulting your doctor.

SIDE EFFECTS OF NICARDIA RETARD 20MG

HOW TO MANAGE SIDE EFFECTS

Feeling sick (nausea) or indigestion:

Stick to simple meals and do not eat rich or spicy foods.

Headache:

Rest and drink plenty of fluids. Ask your doctor to recommend a painkiller.

Dizziness or lightheadedness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Constipation:

Drink sufficient quantity of water every day. Add fruits, vegetables whole grains and other high-fiber foods to your diet.

Cough:

Drink fluids which helps thin the mucus in your throat. Suck on cough drops or hard candies.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

• rifampicin, erythromycin (antibiotic)
• cimetidine (to treat stomach ulcers)
• digoxin, diltiazem, quinidine or beta-blockers (used to treat heart conditions)
• quinupristin/dalfopristin (a combination antibiotic)
• phenytoin, carbamazepine phenobarbital orvalproic acid (to treat epilepsy)
• cisapride (used to treat reduced movements of the gullet and stomach)
• magnesium sulphate injections
• ketoconazole, itraconazole or fluconazole (antifungal medicines)
• indinavir, nelfinavir, ritonavir, saquinavir or amprenavir (used to treat HIV)
• fluoxetine or nefazodone (to treat depression)
• tacrolimus (to prevent the rejection of transplanted organs)
• phenobarbital (treats insomnia or anxiety)
• other medicines to treat high blood pressure

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT NICARDIA RETARD 20MG

Can NICARDIA RETARD 20MG be used in pregnancy and nursing mothers?

Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant or breastfeeding. It should be used only if prescribed by the doctor in case of pregnancy.

Do I need to change my diet while taking NICARDIA RETARD 20MG?

Yes, making small changes to your diet can help your medicine work well. You must take a low sodium and low-fat diet and adhere to the lifestyle changes as advised by your doctor.

Does NICARDIA RETARD 20MG affect blood sugar?

No, it does not cause any change in blood sugar levels. It has been observed that it has no effect on the release of insulin or change in blood sugar levels.

REFERENCES

1. KD Tripathi MD. Anti-anginal and other anti-ischaemic drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 549.

2. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12thed. New York, New York: McGraw-Hill Medical; 2011. Page 757-758.

3. Opie LH. Calcium Channel Blockers. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. Page 84-86.

4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page 978-979.

5. Jenny Bryan, Nifedipine: from the treatment of angina to the treatment of hypertension: The Pharmaceutical Journal; 20 May 2010, [Accessed on Oct 3, 2020] https://www.pharmaceutical-journal.com/opinion/comment/nifedipine-from-the-treatment-of-angina-to-the-treatment-of-hypertension/11011713.article?firstPass=false

6. Morningside Healthcare Ltd; Electronic Medicines Compendium (EMC); [Revised on Sep 2020] [Accessed Oct 3, 2020] https://www.medicines.org.uk/emc/files/pil.9566.pdf

7. Lagaay International BV; [Accessed on Oct 3, 2020] https://www.lagaay.com/Catalogus/Product%20information/018380/Adalat%20capsules%20leaflet.pdf

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count
• Kidney Function Test
• Electrocardiogram