NEXTRIL contains Tofisopam which belongs to the group of medicines called as Benzodiazepine derivatives. It is used in the treatment of anxiety and depression. Anxiety is an intense, excessive, persistent worry and fear about everyday situations which is characterized by symptoms such as fast heart rate, rapid breathing, sweating and tiredness. Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest that affects the way you feel, think, and behave which can lead to variety of emotional and physical problems such as back pain or headache.
Tofisopam works by increasing the action of a chemical messenger in the brain known as GABA (gamma-amino-butyric-acid), which suppresses the excessive and abnormal activity of nerve cells in the brain that results in reducing depression and anxiety.
NEXTRIL is not recommended for use in patients having decompensated respiratory insufficiency (shortness of breath and wheezing), history of coma and sleep apnoea, increased pressure in the eye, chronic psychosis, and obsessive-compulsive phobic disorders. Before taking NEXTRIL, inform your doctor if you have mental illness, personality disorders, atherosclerosis, epilepsy, liver, and kidney disease.
NEXTRIL is not recommended for use in first trimester during pregnancy and in breast-feeding women. It should be used with caution in children and adolescents (below 18 years). The most common side effects of taking NEXTRIL are loss of appetite, vomiting, nausea, constipation, flatulence, dry mouth, and rash. Consult your doctor if any of the symptoms worsen.
NEXTRIL works by increasing the action of a chemical messenger in the brain known as GABA (gamma-amino-butyric-acid), which suppresses the excessive and abnormal activity of nerve cells in the brain that results in reducing depression and anxiety.
Take NEXTRIL as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of NEXTRIL for you depending upon your age, body weight and disease condition.
Constipation:
Try to eat high-fiber foods such as vegetables, cereals, fresh fruits, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate treatments for constipation.
Nausea and vomiting:
Try to take NEXTRIL with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if symptom gets worse.
Flatulence:
Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If it does not improve, contact your doctor.
Loss of appetite:
Eat when you feel hungry. Eat smaller meals frequently than usual. Snack only when you're hungry. Eat a nutritious snack which is rich in calories and protein, such as dried fruit and nuts. Consult your doctor if the symptom does not improve.
NEXTRIL is not recommended for use in pregnant women in the first trimester. It should be used with caution after first three months of pregnancy only if it is clearly necessary. Consult your doctor before taking it.
NEXTRIL is not recommended for use in breastfeeding women as it passes through breast milk. Consult your doctor before taking it.
NEXTRIL might cause hyperactivity and aggressiveness at high doses which might affect your ability to drive and using machines. Consult your doctor before taking NEXTRIL.
Avoid the use of alcohol with NEXTRIL as it may reduce therapeutic efficacy.
[GBNKEYWORD should be used with caution in patients having kidney disease. Consult your doctor before taking NEXTRIL.
NEXTRIL should be used with caution in patients having liver disease. Consult your doctor before taking NEXTRIL.
Do not take NEXTRIL if you are allergic to Tofisopam.
NEXTRIL is not recommended for use in patients having lung diseases such as decompensated respiratory insufficiency (shortness of breath and wheezing). Consult your doctor before taking NEXTRIL.
NEXTRIL is not recommended for use if you:
Before taking NEXTRIL inform your doctor if you:
Use in Pediatrics:
NEXTRIL should be used with caution in children and adolescents (below 18 years). Consult child’s doctor for advice.
Use in Geriatrics:
NEXTRIL should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before taking [GBNKEYORD].
A. Drug – Drug Interactions:
Before taking NEXTRIL inform your doctor if you are taking any of the following medicines:
Overdosage:
If you or anyone else accidentally take too much of NEXTRIL, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of NEXTRIL include vomiting, confusion, coma, respiratory depression, and seizures.
Drug | : | Tofisopam |
Pharmacological Category | : | Benzodiazepine derivative |
Therapeutic Indication | : | Anxiety, Depression |
Dosage Forms | : | Tablet |
What is NEXTRIL and why is it prescribed?
NEXTRIL contains Tofisopam which belongs to the group of medicines called as Benzodiazepine derivatives which is used in the treatment of anxiety and depression. Consult your doctor for advice before taking NEXTRIL.
Is NEXTRIL safe in pregnant and breast-feeding women?
NEXTRIL is not recommended for use in pregnant women in the first trimester. It should be used with caution after first three months of pregnancy. NEXTRIL is not recommended for use in breastfeeding women as it is passed in the breast milk. Consult your doctor before taking NEXTRIL.
Can NEXTRIL affect the ability to drive?
NEXTRIL might cause hyperactivity and aggressiveness at high doses which might affect your ability to drive and using machines. Consult your doctor before taking NEXTRIL.
What if someone takes more NEXTRIL than recommended dose?
If you or anyone else accidentally take too much of NEXTRIL, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are vomiting, confusion, coma, respiratory depression, and seizures.
Can NEXTRIL be given to children?
NEXTRIL should be used with caution in children and adolescents (below 18 years of age) since safety and efficacy not established. Consult child’s doctor for advice before giving NEXTRIL to your children.
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