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INTRODUCTION ABOUT NEXOCAINE ORAL SUSPENSION

NEXOCAINE ORAL SUSPENSION is a combination of Aluminium hydroxide, Magnesium hydroxide, and Oxetacaine, which belong to the group of medicines called Antacids, Laxatives, and Anaesthetics, respectively. It is indicated in the management of gastritis (inflammation of the lining of the stomach), esophagitis (inflammation of the food pipe), hiatus hernia, heartburn during pregnancy, and peptic ulcers.

Along with management with NEXOCAINE ORAL SUSPENSION, your doctor might ask you to make some lifestyle changes, such as eating bland food and having a good liquid diet. Prior to the management of NEXOCAINE ORAL SUSPENSION, your doctor might ask you to take some diagnostic tests to understand the existing condition.

Before taking NEXOCAINE ORAL SUSPENSION, inform your doctor if you have any liver, heart, or lung disease. It should be used with caution in patients with impaired kidney function. NEXOCAINE ORAL SUSPENSION should be used with caution in pregnant and breast-feeding women only if clearly advised by the doctor.

The most common side effects of taking NEXOCAINE ORAL SUSPENSION are nausea, vomiting, constipation, diarrhea, stomach pain, and dizziness. Ask for your doctor’s advice if any of these worsen or don’t improve.

USES OF NEXOCAINE ORAL SUSPENSION

Manages,

Gastritis
Esophagitis (inflammation of the food pipe)
Hiatus hernia
Heartburn from pregnancy
Peptic ulcer

HOW NEXOCAINE ORAL SUSPENSION WORKS

NEXOCAINE ORAL SUSPENSION helps in the management of various gastrointestinal problems, where aluminium hydroxide is an antacid that acts by neutralizing the hydrochloric acid produced by the stomach. It also decreases the pH level in the stomach, stabilizing the acidity. Magnesium hydroxide is a laxative that works by drawing in more water into the intestinal tract. This increases intestinal movements and helps with easy bowel emptying. Oxetacaine is an anaesthetic agent that blocks the nerve pathways and helps in relieving pain and inflammation.

DIRECTIONS FOR USE

Take NEXOCAINE ORAL SUSPENSION as advised by your physician. Shake well before use. Take NEXOCAINE ORAL SUSPENSION, preferably 15 minutes before meals. It is preferable to take it without diluting it. However, a sip of water may be taken if required. Your doctor will decide the correct dose and duration for you depending on your age, disease condition, and body weight.

SIDE EFFECTS OF NEXOCAINE ORAL SUSPENSION

COMMON

Nausea, vomiting
Constipation, diarrhoea
Stomach pain
Drowsiness, dizziness
Rash or redness of the skin
Swelling on the eyes, lips, and tongue

HOW TO MANAGE SIDE EFFECTS

Constipation

Increase fiber intake through fruits, vegetables, and whole grains. Stay hydrated by drinking plenty of water. Maintain regular meal times and avoid skipping meals. Exercise regularly to promote bowel movements. Establish a bathroom routine and avoid ignoring the urge to go. Avoid processed foods and prioritize probiotic-rich foods for gut health. Consult your doctor if constipation persists.

Diarrhea

Drink plenty of clear fluids, like water, diluted fruit juices, or oral rehydration solutions, to stay hydrated. Avoid caffeinated or alcoholic beverages, as they can worsen dehydration. Gradually take bland, low-fiber foods like bananas, rice, applesauce, and toast to help firm up stools. Probiotics, found in yogurt or supplements, may help restore the balance of gut bacteria. Practice good hand hygiene to prevent the spread of infection. Consult your doctor if diarrhea worsens.

Nausea And Vomiting

Stay hydrated with small sips of clear fluids like water, ginger ale, or electrolyte solutions. Avoid consuming large meals; instead, opt for bland, easy-to-digest foods. Ginger, peppermint, or chamomile tea may help soothe the stomach. Rest in a comfortable position, preferably with your head elevated, to ease symptoms. Consult your doctor if nausea and vomiting persist.

Stomach Pain

Avoid spicy or fatty foods, caffeine, or alcohol that may exacerbate symptoms. Eat a bland diet consisting of easily digestible foods like rice, bananas, applesauce, and toast. Applying a heating pad or taking a warm bath can also help soothe abdominal muscles and alleviate discomfort. Drink plenty of fluids to stay hydrated but avoid excessive consumption to prevent further irritation. If stomach pain persists, consult your doctor.

WARNING & PRECAUTIONS

PREGNANCY

Use with Caution

There are no well-controlled studies on the use of NEXOCAINE ORAL SUSPENSION in pregnant women. It should be used with caution by pregnant women only if clearly necessary. Consult your doctor before taking it.

BREASTFEEDING

Use with Caution

There are no well-controlled studies on the use of NEXOCAINE ORAL SUSPENSION in breast-feeding women. It should be used with caution in breast-feeding women only if considered clearly necessary. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Consult your doctor

There is no data available on the effects of NEXOCAINE ORAL SUSPENSION on driving or using machines.

KIDNEY

Use with Caution

NEXOCAINE ORAL SUSPENSION should be used with caution in patients with impaired kidney function. Consult your doctor before taking it.

ALLERGY

Contraindicated

Do not take NEXOCAINE ORAL SUSPENSION if you are allergic to Aluminium hydroxide, Magnesium hydroxide, or Oxetacaine.

USE IN PEDIATRICS

Consult your doctor

The dose requirements of NEXOCAINE ORAL SUSPENSION for young children have not been extensively evaluated. Your child’s doctor will decide the correct dose and duration of the management with NEXOCAINE ORAL SUSPENSION for your child depending upon your child’s age, body weight, and health condition. Consult your child’s doctor for advice.

OTHERS

NEXOCAINE ORAL SUSPENSION is not recommended for use if you have:

Low levels of phosphate in the blood (hypophosphatemia)

INTERACTIONS

A. Drug-Drug Interactions:

Before taking NEXOCAINE ORAL SUSPENSION, inform your doctor if you are taking any of these medicines:

Beta-blocking agents such as propranolol, metoprolol (used to manage high blood pressure), digoxin, and quinidine (used to manage irregular heartbeats)
Cimetidine (used to manage stomach disturbances)
Chloroquine (used to manage malaria)
NSAIDs such as ibuprofen and celecoxib (used to manage pain and inflammation)
Phenytoin (used to manage epilepsy)
Tetracyclines and fluoroquinolones such as levofloxacin (used to manage infections)
Iron preparations

B. Drug-food interactions:

Avoid drinking anything immediately after the consumption of NEXOCAINE ORAL SUSPENSION.

Overdosage:

If you or anyone else accidentally takes too much of NEXOCAINE ORAL SUSPENSION, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of NEXOCAINE ORAL SUSPENSION include electrolyte disturbances, glossitis, dizziness, faintness, and drowsiness.

SYNOPSIS

Drug	:	Aluminium Hydroxide, Magnesium Hydroxide, and Oxetacaine
Pharmacological Category	:	Antacids, Laxatives, and Anaesthetics
Therapeutic Indication	:	Gastritis, esophagitis, hiatus hernia, heartburn during pregnancy, and peptic ulcer
Dosage Forms	:	Oral gel, suspension, syrup

MORE INFORMATION

STORAGE

Keep NEXOCAINE ORAL SUSPENSION out of reach of children
Store at room temperature

FAQs ABOUT NEXOCAINE ORAL SUSPENSION

Q: What is NEXOCAINE ORAL SUSPENSION and why is it prescribed?

A: NEXOCAINE ORAL SUSPENSION is a combination of Aluminium hydroxide, Magnesium hydroxide, and Oxetacaine, which belongs to the group of medicines called Antacids, Laxatives, and Anaesthetics. It is indicated in the management of gastritis, esophagitis (inflammation of the food pipe), hiatus hernia, heartburn during pregnancy, and peptic ulcers.

Q: What are the precautions that I need to take care of while taking NEXOCAINE ORAL SUSPENSION?

A: Avoid the long-term use of NEXOCAINE ORAL SUSPENSION, as it may lead to hypophosphatemia. You should avoid drinking anything immediately after taking NEXOCAINE ORAL SUSPENSION, as it can cause the anaesthetic agent to wash away without exerting its desired effect. Also, you should avoid taking any other oral medication within 1 to 2 hours of consuming NEXOCAINE ORAL SUSPENSION. If you have any further questions, ask for your doctor’s advice.

Q: Can NEXOCAINE ORAL SUSPENSION be used in pregnant and breast-feeding women?

A: There are no well-controlled studies on the use of NEXOCAINE ORAL SUSPENSION in pregnant and breast-feeding women. It should be used with caution if the potential benefit outweighs the potential risk to the baby. Consult your doctor before taking it.

Q: Is NEXOCAINE ORAL SUSPENSION safe to use with children?

A: The dose requirements of NEXOCAINE ORAL SUSPENSION for young children have not been extensively evaluated. A proper diagnosis must be made before taking NEXOCAINE ORAL SUSPENSION. Your doctor will decide the correct dose and duration of the management with NEXOCAINE ORAL SUSPENSION for your child depending upon your child’s age, weight, and health condition. Consult your doctor before taking it.

Q: How do I take NEXOCAINE ORAL SUSPENSION?

A: Take NEXOCAINE ORAL SUSPENSION as advised by your physician. Shake well before use. Take NEXOCAINE ORAL SUSPENSION, preferably 15 minutes before meals. It is preferable to take it without diluting it. However, a sip of water may be taken if required. Your doctor will decide the correct dose and duration for you depending on your age, disease condition, and body weight.

Q: What are the side effects of taking NEXOCAINE ORAL SUSPENSION?

A: The most common side effects of taking NEXOCAINE ORAL SUSPENSION are nausea, vomiting, constipation, diarrhea, stomach pain, and dizziness. Ask for your doctor’s advice if any of these worsen or don’t improve.

Q: How does NEXOCAINE ORAL SUSPENSION work?

A: NEXOCAINE ORAL SUSPENSION helps in the management of various gastrointestinal problems, where aluminium hydroxide is an antacid that acts by neutralizing the hydrochloric acid produced by the stomach. It also decreases the pH level in the stomach, stabilizing the acidity. Magnesium hydroxide is a laxative that works by drawing in more water into the intestinal tract. This increases intestinal movements and helps with easy bowel emptying. Oxetacaine is an anaesthetic agent that blocks the nerve pathways and helps in relieving pain and inflammation.

Q: Who should not take NEXOCAINE ORAL SUSPENSION?

A: Do not take NEXOCAINE ORAL SUSPENSION if you are allergic to Aluminium hydroxide, Magnesium hydroxide, or Oxetacaine or if you have low levels of phosphate in the blood (hypophosphatemia). Consult your doctor before taking it.

Q: Does NEXOCAINE ORAL SUSPENSION cause constipation?

A: Yes, NEXOCAINE ORAL SUSPENSION may cause constipation. Increase fiber intake through fruits, vegetables, and whole grains. Stay hydrated by drinking plenty of water. Maintain regular meal times and avoid skipping meals. Exercise regularly to promote bowel movements. Establish a bathroom routine and avoid ignoring the urge to go. Avoid processed foods and prioritize probiotic-rich foods for gut health. Consult your doctor if constipation persists.

Q: Can I use other medicines along with NEXOCAINE ORAL SUSPENSION?

A: Before taking NEXOCAINE ORAL SUSPENSION, inform your doctor if you are taking prescription, non-prescription, or herbal medicines.

REFERENCES

1. K.D. Tripathi. Drugs for Peptic Ulcer and GERD. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 649.

2. Aluminium Hydroxide. NIH National Library of Medicine, National Center for Biotechnology Information. PubChem. [Accessed on 4th July 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Aluminum-hydroxide

3. Oxetacaine. NIH National Library of Medicine, National Center for Biotechnology Information. PubChem. [Accessed on 4th July 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Oxethazaine

4. Iacono G, Carroccio A, Montalto G, Cavataio F, Ippolito S, Kazmierska I, and Balsamo V. Magnesium hydroxide and aluminium hydroxide in the treatment of gastroesophageal reflux. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed.gov. December 1991 [Accessed on 4th July 2024] https://pubmed.ncbi.nlm.nih.gov/1798406/

5. Leeford Healthcare Ltd. Dynacaine Liquid Gel (Aluminium Hydroxide, Magnesium Hydroxide, and Oxetacaine). [Accessed on 4th July 2024] https://www.leeford.in/product/269/dynacaine

6. Saar Biotech. Oxetacaine, Aluminium, Magnesium Suspension. [Accessed on 4th July 2024] https://saarbiotech.in/Oxetacaine%20+%20Aluminum%20hydroxide%20+%20Magnesium%20hydroxide.html

7. Pfizer Ltd. Mucaine Gel (Aluminium Hydroxide, Magnesium Hydroxide, and Oxetacaine). [Accessed on 4th July 2024] https://labeling.pfizer.com/ShowLabeling.aspx?id=14808

USEFUL DIAGNOSTIC TESTS

Complete Blood Count (CBC)/ Hemogram
Monsoon Gastro Infection Panel
Gastro / Gut Health Panel
Healthy Midlife Checkup
Men Health Checkup – Advanced
Complete Women Checkup
Full Body Checkup - Gold
Elderly Checkup - Female
Elderly Checkup - Male

AUTHOR DETAILS

Written By Dr. N. Sai Swaroop - Pharm.D

Last updated on 05 Jul 2024 | 03:35 PM(IST)

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