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Ranbaxy Laboratories Ltd

Neupent AF 450mg Tablet 10'S

Epilepsy/Convulsion
MRP ₹176.00 (Inclusive of all taxes)
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    Introduction About NEUPENT AF 450MG TABLET

    NEUPENT AF 450MG TABLET is used in the management of various forms of epilepsy alone or in combination with other medicine and manages peripheral neuropathic pain.

    It contains Gabapentin which is an anticonvulsant agent that controls seizures and neuropathic pain by altering the electrical activity in the brain.

    NEUPENT AF 450MG TABLET should be used under medical supervision only. Do not stop taking NEUPENT AF 450MG TABLET suddenly, as this may lead to increased risk of seizures.

    This medicine should be used with caution patients having kidney problems, are on hemodialysis, muscle pain and/or weakness, suffer with different types of seizures including absences, persistent stomach pain, feeling sick and being sick (symptoms of inflamed pancreas), history of drug dependence or abuse, intolerance to certain sugar, have nervous system or respiratory disorders.

    NEUPENT AF 450MG TABLET is not recommended for use in pregnant and breastfeeding women. It is not recommended for use in children aged below 6 years and should be used with caution in elder patients 65 years of age and above.

    One of the serious side effects associated with NEUPENT AF 450MG TABLET is self-harming thoughts, contact your doctor immediately if you experience such unusual reactions. The most common side effects of taking NEUPENT AF 450MG TABLET are dizziness, drowsiness, blurred vision, viral infection, lack of coordination.

    Uses Of NEUPENT AF 450MG TABLET

    It is used to manage:

    • Various forms of epilepsy (fits)
    • Peripheral neuropathic pain

    How NEUPENT AF 450MG TABLET Works

    NEUPENT AF 450MG TABLET works effectively by altering the electrical activity in the brain by inhibiting the voltage-gated calcium channels and decreasing the release of excitatory neurotransmitters, thus managing fits or seizures. It also blocks the pain signals travelling through the damaged nerves and the brain and manages nerve pain.

    How to use NEUPENT AF 450MG TABLET

    Take NEUPENT AF 450MG TABLET as directed by your physician. Swallow it as whole with a glass full of water. Do not crush or chew the medicine. Correct dosage and duration will be prescribed by your doctor depending upon your age, body weight, and health condition.

    Side Effects Of NEUPENT AF 450MG TABLET

    Common Side Effects of NEUPENT AF 450MG TABLET:

    • Fever, Chills, Runny nose, Cough
    • Drowsiness, Dizziness
    • lack of coordination, Tiredness
    • Pneumonia
    • Signs of upper respiratory tract infection (sore throat, inflamed sinuses, common cold)
    • Signs of urinary tract infection (bladder pain, foul smell, cloudy urine, frequent urination)
    • Inflammation of the ear or other infections
    • Eating disorder characterized by low body weight and increased appetite
    • Anger towards others, confusion, mood changes, depression, anxiety, nervousness, difficulty with thinking
    • Jerky movements, difficulty with speaking, loss of memory, tremor, difficulty sleeping, headache, sensitive skin, decreased sensation (numbness), difficulty with coordination, unusual eye movement, increased, decreased or absent reflexes
    • Blurred or double vision
    • High blood pressure, flushing
    • Difficulty in breathing, bronchitis
    • Vomiting, nausea  
    • Problems with teeth, inflamed gums
    • Diarrhea, stomach pain, indigestion, constipation, flatulence
    • Joint pain, back pain, twitching
    • Difficulties with erection (male)
    • Swelling in the legs and arms, difficulty with walking, weakness, pain,

    Stop taking NEUPENT AF 450MG TABLET and contact your doctor immediately if you experience any of the following side effects:

    • Yellowing of your skin or of the whites of the eyes
    • Unusual bruising or bleeding
    • Severe weakness
    • Unexplained muscle pain
    • Frequent infections

    Warning & Precautions

    Pregnancy

    Monitoring required

    NEUPENT AF 450MG TABLET is not recommended for use in pregnant woman or women planning to have a baby unless prescribed by your doctor. Effective contraception must be used by women of child-bearing potential.

    Breastfeeding

    Contraindicated

    NEUPENT AF 450MG TABLET is not recommended for use in breast-feeding women as it may pass through breast milk.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any machines, because NEUPENT AF 450MG TABLET may cause dizziness, drowsiness and tiredness.

    Kidney

    Use with Caution

    NEUPENT AF 450MG TABLET should be used with caution in patients with kidney problems or undergoing hemodialysis.

    Allergy

    Contraindicated

    Do not take NEUPENT AF 450MG TABLET if you are allergic to Gabapentin or any other ingredients of this medicine.

    Use In Pediatrics

    Contraindicated

    NEUPENT AF 450MG TABLET is not recommended for use in children aged below 6 years.

    Use In Geriatrics

    Use with Caution

    NEUPENT AF 450MG TABLET should be taken with caution in elderly patients aged 65 years or above. The dose will be adjusted by your doctor.

    Others

    Before taking NEUPENT AF 450MG TABLET, inform your doctor if you:

    • Have acute pancreatitis with signs of persistent stomach pain, feeling sick and being sick)
    • Have nervous system disorders, respiratory disorders
    • Have muscle pain and/or weakness
    • Suffer with different types of seizures including absences
    • Have history of drug dependence or abuse
    • Have intolerance to certain sugars

    Interactions

    A. Drug-Drug interactions:

    Before taking NEUPENT AF 450MG TABLET inform your doctor if you are taking any of the following medicines:

    • Medicines containing opioids such as morphine (used to manage pain)
    • Antacids such as aluminum hydroxide and magnesium hydroxide (medicines used to reduce heart burn, indigestion)
    • Other medicines for convulsions (Ex. carbamazepine, phenytoin)
    • Sleeping disorders (Ex. benzodiazepines)
    • Depression, anxiety (Ex. fluoxetine)

    Overdosage:

    If you or anyone else accidentally takes too much of NEUPENT AF 450MG TABLET, consult your doctor immediately or visit the nearby hospital. Signs of overdose includes loss of consciousness, dizziness, double vision, slurred speech, drowsiness, tiredness, and diarrhoea.

    Synopsis

    Drug :   Gabapentin
    Pharmacological Category :   Anticonvulsants
    Therapeutic Indication :   Epilepsy, Peripheral neuropathic pain
    Dosage Forms :   Tablet, Capsule

    FAQs About NEUPENT AF 450MG TABLET

    Q: What is NEUPENT AF 450MG TABLET and why is it given?

    A: NEUPENT AF 450MG TABLET contains Gabapentin which is an Antiepileptic. NEUPENT AF 450MG TABLET is used to manage epilepsy (fits) and peripheral neuropathic pain (long term pain caused by damage to the nerves).

    Q: How does NEUPENT AF 450MG TABLET work?

    A: NEUPENT AF 450MG TABLET works effectively by altering the electrical activity in the brain by inhibiting the voltage-gated calcium channels and decreasing the release of excitatory neurotransmitters, thus managing fits or seizures. NEUPENT AF 450MG TABLET also blocks the pain signals travelling through the damaged nerves and the brain and manages nerve pain.

    Q: How to take NEUPENT AF 450MG TABLET be?

    A: Take NEUPENT AF 450MG TABLET as directed by your physician. Swallow it as whole with a glass full of water. Do not crush or chew the medicine. Correct dosage and duration will be prescribed by your doctor depending upon your age, body weight, and health condition.

    Q: Can NEUPENT AF 450MG TABLET be stopped on our own?

    A: Do not stop taking NEUPENT AF 450MG TABLET suddenly on your own, as it may lead to increased risk of seizure. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

    Q: Is NEUPENT AF 450MG TABLET safe in pregnant and breast-feeding women?

    A: NEUPENT AF 450MG TABLET is not intended for use in pregnant woman unless recommended by your doctor and in breast-feeding woman as it may pass through breast milk to the baby. Consult your doctor about the risk and benefits before taking NEUPENT AF 450MG TABLET.

    Q: Is NEUPENT AF 450MG TABLET safe for use in elderly patients?

    A: NEUPENT AF 450MG TABLET is suitable for use in elderly patients aged 65years and above. Correct dosage and duration will be prescribed by your physician. Consult your doctor before taking NEUPENT AF 450MG TABLET.

    Q: Does NEUPENT AF 450MG TABLET causes dizziness?

    A: Yes, NEUPENT AF 450MG TABLET may cause dizziness. Lie, or sit down immediately when you feel dizzy. If you're feeling a severe episode of vertigo, lie in a dark and quite place with eyes closed. Talk to your doctor if the symptom does not improve.

    References

    1. KD. Tripathi. Antiepileptics. Essentials of medical pharmacology. Eighth edition. 2019. Page – 439-442.

    2. Mariangela Panebianco, Sarah Al-Bachari, Jennifer Weston, Jane L Hutton, Anthony G Marson, Cochrane Epilepsy Group. Gabapentin add-on treatment for drug-resistant focal epilepsy. National Library of Medicine, National center for biotechnology information. PubMed Central. 2018. [Accessed 13th June 2022] click here

    3. Rama Yasaei; Shravan Katta; Abdolreza Saadabad. Gabapentin. National Library of Medicine, National center for biotechnology information. May 2022. [Accessed 13th June 2022] click here

    4. Accord, Barnstaple. Electronic Medicines Compendium (EMC). [Revised in May 2022].  [Accessed 13th June 2022] click here

    5. APL Swift Services (Malta) Limited. Electronic Medicines Compendium (EMC). [Revised in January 2021] [Accessed 13th June 2022] click here

    Author Details

    Written By Srilekha. R - B.Pharm
    Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)
    Last updated on 18 Nov 2024 | 03:36 PM(IST)
    Lab updated