INTRODUCTION

NASOMIST X contains Xylometazoline which belongs to the group of medicines called Nasal decongestants. It is used in adults and in adolescents (aged 12 years or above) to provide relief from nasal congestion. It can also be used to provide relief from unpleasant symptoms of nasal cavity (such as nasal block, itching or discomfort) caused due to sinusitis (inflammation of the sinuses) or allergic rhinitis (an allergic condition)

Always use NASOMIST X as directed by your physician. It is for intranasal use only. Do not use NASOMIST X for more than 7 days without consulting your doctor.

Before using NASOMIST X inform your doctor if you have diabetes, hypertension, glaucoma, hyperthyroidism or any heart problems. You must also inform your doctor if you have any other problems in nasal tract apart from nasal congestion such as chronic nasal inflammation with very dry nasal passages (rhinitis sicca or atrophic rhinitis).

Consult your doctor before using NASOMIST X if you are pregnant, think you may be pregnant or breastfeeding. The most common side effects of using NASOMIST X are irritation or burning sensation after application and nasal dryness. Consult your doctor if any of these side effect worsens.

USES OF NASOMIST X

It is used in adults and in adolescents (aged 12 years or above) to provide relief from:

• Nasal congestion (blocked nose)

HOW NASOMIST X WORKS

NASOMIST X opens and clears the nasal passages. It works by narrowing down the blood vessels supplying the nasal passage. This helps swollen blood vessels of the nasal tract to return to its normal size which allows the air to pass through the nostrils more freely. It also reduces the excessive nasal secretions and provides temporary relief from nasal inflammation, swelling and discomfort.

DIRECTIONS FOR USE

Always use NASOMIST X as directed by your physician. It is for intranasal use only.

For Nasal Drops: Gently instill few drops of this medicine into each nostril. Clean the dropper after application.

For Nasal Spray: Insert the spray nozzle inside the affected nostril. Press the pump to release the spray and sniff at the same time. Repeat the same to the other nostril if required. Clean the nozzle after application.

To avoid possible spread of infection, this pack should only be used by a single person. Do not use NASOMIST X for more than 7 days without consulting your doctor. Discard the unused portion after 28 days of opening it.

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Nausea

Take NASOMIST X with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before using NASOMIST X, inform your doctor if you are taking any of the following medicines:

• antidepressants (used to treat depression) such as monoamine oxidase inhibitors (Ex. moclobemide, isocarboxazid, phenelzine and tranylcypromine), tricyclic antidepressants (Ex. amitriptyline, nortriptyline), lithium, fluoxetine, sertraline, citalopram, escitalopram etc
• medicines used to control blood pressure such as alpha blockers (Ex. prazosin, terazocin) or beta blockers (Ex. propranolol, atenolol)
• timolol, betaxolol (used to treat glaucoma in the eye)

Overdosage:

If you or anyone else accidentally applied too much of NASOMIST X, consult your doctor immediately.

SYNOPSIS

MORE INFORMATION

• Keep NASOMIST X out of reach to children
• Store NASOMIST X at room temperature

FAQs ABOUT NASOMIST X

What is the use of NASOMIST X?

NASOMIST X is used to provide relief from nasal congestion caused due to common cold, sinusitis or allergic rhinitis.

Can NASOMIST X be used every day?

Use NASOMIST X for the duration prescribed by your doctor. Do not use NASOMIST X for more than 7 days without consulting your doctor. Prolonged use of NASOMIST X may worsen your condition.

Is it safe to use NASOMIST X?

Yes. NASOMIST X is one of the safe and well tolerated medicine. It does not cause any harmful side effects. It may cause local irritation or burning sensation after application which is quite normal and disappears after few minutes.

What are the side effects of NASOMIST X?

The most common side effects of using NASOMIST X are irritation or burning sensation after application and nasal dryness. Consult your doctor if they bother you.

Can NASOMIST X be used in children?

NASOMIST X can be used in children and adolescents aged 12 years or above. You must consult your doctor before using NASOMIST X if your child is aged 6 years or above. It is not recommended for use in children aged below 6 years. Therefore, consult your doctor for advice before administration.

Is NASOMIST X an antihistamine?

NASOMIST X is a sympathomimetic agonist. It directly acts on the alpha-adrenergic receptors of the blood vessels supplying the nasal tract and narrows them down. This reduces swelling of the nasal tract and allows the air to pass through the nostrils more freely.

How long it takes for NASOMIST X to work?

NASOMIST X may show its therapeutic effect after 5 to 10 minutes of application. It works by narrowing of blood vessels in the affected lining of the nose and helps to provide relief from congestion.

Can NASOMIST X cause rebound congestion?

Yes, NASOMIST X may cause rebound congestion (worsening of congestion due to nasal decongestant sprays) if you use for more than the duration recommended by your doctor.

REFERENCES

1. K.D. Tripathi. Adrenergic System and Drugs. Essential of Medical Pharmacology. 7th Edition. Page – 136.

2. Xylometazoline. ScienceDirect.com. [Accessed on 30th August 2022]. https://www.sciencedirect.com/topics/medicine-and-dentistry/xylometazoline#:~:text=Clinical%20Pharmacology%3A,Therapeutic%20Effect%3A%20Decreased%20nasal%20congestion.

3. Ronald Eccles, Kaj Martensson and Shirley C. Chen. Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold. Taylor Francis Online. January 2010. [Accessed on 30th August 2022]. https://www.tandfonline.com/doi/abs/10.1185/03007991003648015?journalCode=icmo20

4. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 30th August 2022]. https://www.medicines.org.uk/emc/files/pil.5984.pdf

5. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 30th August 2022]. https://www.medicines.org.uk/emc/files/pil.1412.pdf