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Drug Information

What is Oxymetazoline Hydrochloride used for?

Oxymetazoline Hydrochloride is used for the treatment of nasal congestion caused due to common cold, sinusitis and hay fever.

Oxymetazoline Hydrochloride may also be prescribed for other conditions as determined by the doctor.

How does Oxymetazoline Hydrochloride work?

Oxymetazoline Hydrochloride belongs to the class of drugs called nasal decongestants. This drug acts by binding to certain receptors and constricts the blood vessels in the nose, which helps in decreasing swelling and nasal congestion.

How to use Oxymetazoline Hydrochloride?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Use Oxymetazoline Hydrochloride as prescribed by your doctor.

  • Gently insert the tip of Oxymetazoline Hydrochloride nasalspray into one nostril, squeeze the bottle and breathe in deeply.
  • Use Oxymetazoline Hydrochloride nasal drops as directed by your physician.

If you miss a dose of Oxymetazoline Hydrochloride, please use immediately once you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use a double dose to compensate for the missed dose.

The overdose symptoms of Oxymetazoline Hydrochloride include the following:

  • Severe drowsiness
  • Decreased heartbeat
  • Dizziness
  • Fainting

You must seek immediate medical care if you experience any of the above symptoms.

What are the drugs that interact with Oxymetazoline Hydrochloride?

Drugs that interact with Oxymetazoline Hydrochloride include the following:

  • Albuterol
  • Ergotamine
  • Formoterol
  • Furazolidone
  • Guanethidine
  • Isocarboxazid
  • Isoproterenol
  • Linezolid
  • Methylergonovine
  • Methysergide maleate
  • Milnacipran
  • Rasagiline
  • Reserpine
  • Terbutaline
  • Venlafaxine
This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Oxymetazoline Hydrochloride?

The following are the most common side effects of Oxymetazoline Hydrochloride:

  • Temporary burning
  • Stinging
  • Nose dryness
  • Runny nose
  • Sneezing

The following are the severe side effects and you may require immediate medical attention:

  • Dizziness
  • Nausea
  • Headache
  • Mental/mood alterations
  • Trouble sleeping
  • Tremors
  • Unusual weakness

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while using Oxymetazoline Hydrochloride?

  • Avoid using the medicine if you are allergic to Oxymetazoline Hydrochloride or similar drugs.
  • Blow your nose before use.
  • Keep the medication out of reach of children.
  • Do not stop using the medication abruptly unless instructed by the doctor. Stopping the medication suddenly may cause the illness to return.
  • Avoid sneezing or blowing your nose at least for few minutes after using Oxymetazoline Hydrochloride.
  • Do not exceed the dose more than what is prescribed.
  • Avoid using Oxymetazoline Hydrochloride if you are pregnant as the safe use of the drug is not yet established.
  • Do not drive or operate heavy machinery if Oxymetazoline Hydrochloride causes blurred vision or dizziness.

You are advised not to use Oxymetazoline Hydrochloride if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before using Oxymetazoline Hydrochloride?

  • Tell your doctor if you have any medical condition like diabetes, heart disorders overactive thyroid and high blood pressure.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Notify your doctor if you are pregnant or breastfeeding.

Frequently asked questions about Oxymetazoline Hydrochloride

  1. How should Oxymetazoline Hydrochloride be stored?
  2. Oxymetazoline Hydrochloride should be stored at room temperature away from heat, sunlight and radiation.

  3. What are the contraindications of Oxymetazoline Hydrochloride?
  4. Oxymetazoline Hydrochloride is contraindicated in the patients with hyperthyroidism, angina and hypertension.

  5. Do I need to be monitored for any blood parameters while using Oxymetazoline Hydrochloride?
  6. Yes, it is advised to monitor blood sugar levels regularly while using Oxymetazoline Hydrochloride.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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