MYOSTIGMIN 0.5mg Injection 1ml

Urinary Retention Rx required

MRP  ₹ 4.35
(Inclusive of all taxes) * Mkt: Neon Laboratories Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

MYOSTIGMIN 0.5MG INJECTION contain Neostigmine which belongs to a group of medicine called Cholinergic drugs. It is mainly used for the treatment of myasthenia gravis (a chronic autoimmune disorder in which antibodies destruct the communication between nerves and muscle, characterised by weakness in the arm and leg muscles, double vision, trouble speaking and chewing).

MYOSTIGMIN 0.5MG INJECTION is also used to reverse the effects of muscle relaxants, normalise intestinal movements and treat urinary retention after surgery. MYOSTIGMIN 0.5MG INJECTION is not recommended for use if you have blockage in your intestine or face difficulty urinating, have peritonitis or any condition where your intestines may no longer be functioning.

Before receiving MYOSTIGMIN 0.5MG INJECTION tell your doctor if you have asthma, fits, stomach ulcer, Parkinson’s disease or any heart problem. MYOSTIGMIN 0.5MG INJECTION should be used with caution in pregnant and breast-feeding women.

Your doctor will prescribe the right dose of MYOSTIGMIN 0.5MG INJECTION for your child depending on their age, body weight and disease condition.The most common side effects of receiving MYOSTIGMIN 0.5MG INJECTION are slow heartbeat, nausea and vomiting. Contact your doctor if any of the symptoms get worse over time.

USES OF MYOSTIGMIN 0.5MG INJECTION

Used to:

  • Treat myasthenia gravis
  • Reverse the effect of muscle relaxants
  • Normalise intestinal movements
  • Treat urinary retention after surgery

HOW MYOSTIGMIN 0.5MG INJECTION WORKS

MYOSTIGMIN 0.5MG INJECTION increases muscle strength by blocking the action of an enzyme in the body which blocks nerve impulses to muscles. By stopping this enzyme from working, it strengthens muscles and thus helps in easing of intestinal movements and urinary retention.

DIRECTIONS FOR USE

MYOSTIGMIN 0.5MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration of treatment for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF MYOSTIGMIN 0.5MG INJECTION

COMMON

  • increased or decreased heart rate, low blood pressure
  • dry mouth, nausea, vomiting
  • throat pain, procedural complication or pain
  • dizziness, headache, postoperative shivering, prolonged neuromuscular blockade causing paralysis of the affected skeletal muscles
  • difficulty in sleeping
  • difficulty in breathing
  • pruritus (itchy skin)

RARE

Stop receiving MYOSTIGMIN 0.5MG INJECTION and contact your doctor immediately if you experience any of the following side effects:

  • angioedema or a severe allergic reaction (swelling of the face, lips or throat which makes it difficult to swallow or breathe, rash, itching, hives, dizziness)

HOW TO MANAGE SIDE EFFECTS

Nausea or Vomiting:

Take regular sips of a cold drink. Have ginger or peppermint tea. Stick to simple meals. Avoid eating oily or spicy foods. Get adequate rest. Eat when you feel like it. If symptoms persist, contact your doctor.

Dizziness:

Lie or sit down immediately when you feel dizzy. If you're feeling severe episode of spinning (vertigo), lie in a dark and quite place with eyes closed. Try to avoid vehicle driving. If symptom persists, contact your doctor.

Headache:

Apply hot or cold-water bag on your head. Try to take rest in a quiet and dark room. Drink tea or coffee. Massage on scalp or head with mild pressure. If symptom persists, contact your doctor.

Dry mouth:

Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. If symptom persists, contact your doctor.

Skin rash:

Avoid hot showers because hot water can irritate the skin. Do not rub or scratch the rash area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If symptom persists, contact your doctor.

WARNING & PRECAUTIONS

PREGNANCY

MYOSTIGMIN 0.5MG INJECTION should be used with caution in women who are pregnant or planning to become pregnant. Consult your doctor for advice.

BREASTFEEDING

MYOSTIGMIN 0.5MG INJECTION should be used with caution in breastfeeding women. Consult your doctor for advice.

DRIVING AND USING MACHINES

Do not drive or handle any machines if you are affected in any way after receiving MYOSTIGMIN 0.5MG INJECTION.

KIDNEY

No dose adjustment of MYOSTIGMIN 0.5MG INJECTION is required in patients having kidney disease, although, close monitoring maybe needed. Consult your doctor for advice.

LIVER

No dose adjustment of MYOSTIGMIN 0.5MG INJECTION is required in patients having liver disease, although, close monitoring maybe needed. Consult your doctor for advice.

ALLERGY

Do not receive MYOSTIGMIN 0.5MG INJECTION if you are allergic to Neostigmine or any of the other ingredients of this medicine.

LUNGS

MYOSTIGMIN 0.5MG INJECTION should be used with caution in patients having asthma. Consult your doctor for advice.

HEART DISEASE

MYOSTIGMIN 0.5MG INJECTION should be used with caution in patients having heart disease or a slow pulse. Consult your doctor for advice.

OTHERS

MYOSTIGMIN 0.5MG INJECTION is not recommended for use if you have:

  • an intestinal obstruction or difficulty urinating
  • peritonitis (infection or inflammation of the outer layer of your stomach or bowel)
  • improper bowel functioning

Before receiving MYOSTIGMIN 0.5MG INJECTION, inform your doctor if you have:

  • epilepsy (fits)
  • vagotonia (sweating, constipation, involuntary movements)
  • an overactive thyroid gland
  • stomach ulcer
  • Parkinson’s Disease
  • an anastomosis (an opening made by surgery, trauma or disease) in your intestine

Use in Pediatrics:

Your doctor will prescribe the right dose of MYOSTIGMIN 0.5MG INJECTION for your child depending on their age, body weight and disease condition.

Use in Geriatrics:

MYOSTIGMIN 0.5MG INJECTION should be received with caution in elderly patients. Consult your doctor for advice.

INTERACTIONS

A. Drug - Drug interactions:

Before receiving MYOSTIGMIN 0.5MG INJECTION, inform your doctor if you are taking any of the following medicines:

  • certain group of medicines used to treat bacterial infections (Ex. amikacin, gentamycin)
  • suxamethonium (used to relax muscle during surgery)

Overdosage:

MYOSTIGMIN 0.5MG INJECTION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms like nausea, vomiting, diarrhea, sweating, increased bronchial and salivary secretions and slow heartbeat.

SYNOPSIS

Drug :   Neostigmine
Pharmacological Category :   Anticholinesterases
Therapeutic Indication :   Myasthenia gravis, To increase muscle strength
Dosage Forms :   Tablet, Injection

MORE INFORMATION

  • Keep MYOSTIGMIN 0.5MG INJECTION out of reach of children
  • Store MYOSTIGMIN 0.5MG INJECTION below 25°C

FAQs ABOUT MYOSTIGMIN 0.5MG INJECTION

What should I do if I forget to receive a dose of MYOSTIGMIN 0.5MG INJECTION?

Please stick to the prescribed schedule as agreed with your doctor for optimal efficacy of MYOSTIGMIN 0.5MG INJECTION treatment. Tell your doctor whenever you forget to receive any dose.

Can MYOSTIGMIN 0.5MG INJECTION be taken in pregnancy?

Please tell your doctor if you are or think you may be pregnant or are planning to become pregnant before receiving MYOSTIGMIN 0.5MG INJECTION. Although there are no known untoward effects of this medicine, your doctor will advise the correct course of treatment.

Can MYOSTIGMIN 0.5MG INJECTION be stopped?

Continue receiving MYOSTIGMIN 0.5MG INJECTION until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. Call your doctor in such case.

Can MYOSTIGMIN 0.5MG INJECTION be used in asthmatic patients?

MYOSTIGMIN 0.5MG INJECTION should be used with caution in patients having a lung disease called asthma. Consult your doctor for advice. Your doctor will determine a proper dose or select a suitable alternative treatment for you.

Can I take other medicines with MYOSTIGMIN 0.5MG INJECTION?

Before receiving MYOSTIGMIN 0.5MG INJECTION, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, over the counter or any herbal medicine, as these might lead to serious side effects by interacting with each other.

REFERENCES

1. KD. Tripathi. Cholinomimetic Alkaloids. Essentials of medical pharmacology. Eighth edition. 2019. Page – 119.

2. Ji W, Zhang X, Liu J, et al. Efficacy and safety of neostigmine for neuromuscular blockade reversal in patients under general anesthesia: a systematic review and meta-analysis. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. November 2021. [Accessed on 2nd July 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667102/

3. Jie Luo , Shuting Chen , Su Min , Lihua Peng.  Reevaluation and update on efficacy and safety.  of neostigmine for reversal of neuromuscular blockade. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. December 2018. [Accessed on 2nd July 2022]. https://pubmed.ncbi.nlm.nih.gov/30573962/

4. Siegfried Hameln GmbH. Electronic Medicines Compendium (EMC) [Revised in November 2021]. [Accessed on 2nd July 2022].    https://www.medicines.org.uk/emc/files/pil.6268.pdf

5. Dr. Reddy’s Laboratories Inc. Neostigmine injection. [Revised in February 2021] [Accessed on 2nd July 2022]. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=81243f47-bd25-bd02-518a-087badcca755&type=display

PRODUCT DETAILS

    Net Qty
    1 N
    Ingredient
    Neostigmine Methyl Sulphate 0.5 MG
    Hsn Code
    30039034
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

MYOSTIGMIN 0.5mg Injection 1ml

MYOSTIGMIN 0.5mg Injection 1ml Mkt: Neon Laboratories Ltd

M.R.P.: Rs.4.83
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