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Drug Information

What is Chlorzoxazone + Paracetamol combination used for?

Chlorzoxazone + Paracetamol combination tablet is used for the treatment of pain.

Chlorzoxazone + Paracetamol combination may also be prescribed for other conditions as determined by the doctor.

How does Chlorzoxazone + Paracetamol combination work?

In Chlorzoxazone + Paracetamol combination, Chlorzoxazone belongs to the class of drugs called muscle relaxants. This drug acts by inhibiting certain spinal cord and brain refluxes, thereby helping in the reduction of muscle spasm and pain.

Paracetamol belongs to the class of drugs called analgesics. This drug acts by blocking pain impulse generation. Thus, it helps in pain reduction.

How to take Chlorzoxazone + Paracetamol combination?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Chlorzoxazone + Paracetamol combination tablet as prescribed by your doctor.

  • Swallow the tablet Do not crush or chew the tablet.

If you miss a dose of Chlorzoxazone + Paracetamol combination, please take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

What are the drugs that interact with Chlorzoxazone + Paracetamol combination?

Drugs that interact with Chlorzoxazone + Paracetamol combination include the following:

  • Codeine
  • Epinephrine
  • Fentanyl
  • Leflunomide
  • Lidocaine
  • Methadone
  • Morphine
  • Naloxone
  • Oxycodone
  • Phenylephrine

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Chlorzoxazone + Paracetamol combination?

The following are the most common side effects of Chlorzoxazone + Paracetamol combination:

  • Headache
  • Skin rash
  • Stomach pain
  • Vomiting
  • Wheezing
  • Nausea
  • Abdominal distress
  • Trouble breathing

The following are the severe side effects and you may require immediate medical attention:

  • Fever
  • Constipation
  • Loss of appetite
  • Tightness in the chest
  • Unusual tiredness 

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Chlorzoxazone + Paracetamol combination?

  • Avoid taking the medicine if you are allergic to Chlorzoxazone + Paracetamol combination or similar drugs.
  • Avoid consumption of alcohol as it may alter the absorption of Chlorzoxazone + Paracetamol combination.
  • Avoid Chlorzoxazone + Paracetamol combination during pregnancy or breastfeeding because the safe use of the drug is not yet established.
  • Do not exceed the dose prescribed by the doctor.
  • Keep the medication out of reach of children.

You are advised not to take Chlorzoxazone + Paracetamol combination if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Chlorzoxazone + Paracetamol combination?

  • Tell your doctor if you have any history of kidney or liver disorder.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.

Frequently Asked Questions about Chlorzoxazone + Paracetamol combination

  1. Is it common to experience diarrhoea while taking Chlorzoxazone + Paracetamol combination? 
  2. No. Diarrhoea is a side effect of Chlorzoxazone + Paracetamol combination. If you experience diarrhoea while Chlorzoxazone + Paracetamol combination, consult your doctor immediately.

  3. Can I use ketoconazole while taking Chlorzoxazone + Paracetamol combination?
  4. No. It is not advisable to use ketoconazole while taking Chlorzoxazone + Paracetamol combination, as these drugs interact and cause unwanted side effects.

  5. Is it safe to alter the dose of Chlorzoxazone + Paracetamol combination? 
  6. No. It is unsafe to alter the dose of the Chlorzoxazone + Paracetamol combination. It is advisable to consult the doctor before altering the dose.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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