INTRODUCTION

MOTILIUM M contain domperidone which belongs to a group of medicine called dopamine antagonists. It is used to treat nausea and vomiting in adults and adolescents. It increases the movement of food through the stomach and the digestive tract more quickly, thus reducing the feeling of bloating, fullness and indigestion. It works by blocking the action of a chemical in your brain which causes the feeling of nausea and vomiting.

It must be taken 15 to 30 minutes before a meal. Try to take MOTILIUM M at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine. It is strictly not recommended for use in children and adolescents under 12 years of age and older with a body weight of less than 35kg. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine. The most common side effect of this medicine is dry mouth.

USES OF MOTILIUM M

• Treat nausea and vomiting

HOW MOTILIUM M WORKS

MOTILIUM M increases the movement of food through the stomach and the digestive tract more quickly, thus reducing the feeling of bloating, fullness and indigestion. It also works by blocking the action of a chemical in your brain which causes the feeling of nausea and vomiting.

DIRECTIONS FOR USE

Always take MOTILIUM M exactly as your doctor has told you. This medicine must be taken 15 to 30 minutes before a meal. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF MOTILIUM M

HOW TO MANAGE SIDE EFFECTS

Itching:

Moisturize your skin. Apply cooling agents such as menthol and calamine or apply a cold, wet cloth, or ice pack on the itching area.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking,

• azole anti-fungals, specifically oral ketoconazole, fluconazole or voriconazole (used to treat fungal infections)
• antibiotics such as erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine (used to treat bacterial infections)
• amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol, diltiazem, verapamil (used to treat heart problems or high blood pressure)
• haloperidol, pimozide, sertindole (used to treat psychoses)
• citalopram, escitalopram (used to treat depression)
• cisapride, dolasetron, prucalopride (used to treat Gastro-intestinal disorders)
• mequitazine, mizolastine (used to treat allergy)
• halofantrine (used to treat malaria)
• protease inhibitors (used to treat AIDS/HIV)
• toremifene, vandetanib, vincamine (used to treat cancer)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT MOTILIUM M

Is MOTILIUM M an over-the-counter drug?

No, it is not an over the counter (OTC) medicine and it is not advisable to take without a prescription.

Does MOTILIUM M raise the blood pressure?

The increase in blood pressure is generally not seen with the use of this medicine. But if you experience an increase in blood pressure while using this medicine, please consult your doctor.

Can I take MOTILIUM M for morning sickness?

No, it is not indicated or recommended for treating morning sickness.

REFERENCES

1. KD Tripathi. Antiemetic, Prokinetic and Digestant Drugs. Essentials of Medical Pharmacology. Seventh Edition,2013. Page - 666-667.

2. A J Reyntjens, C J Niemegeers, J M Van Nueten, P Laduron, J Heykants, K H Schellekens, R Marsboom, A Jageneau, A Broekaert, P A Janssen. Domperidone, a novel and safe gastrokinetic anti-nauseant for the treatment of dyspepsia and vomiting. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov.1978. [Accessed 06 Feb 2021] https://pubmed.ncbi.nlm.nih.gov/582708/

3. S.C. Zentiva S.A; Electronic Medicines Compendium (EMC); [Revised on Mar 2020] [Accessed 06 Feb 2021] https://www.medicines.org.uk/emc/files/pil.4177.pdf