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Introduction About MONOLOC 25MG INJECTION
MONOLOC 25MG INJECTION contains Ranitidine which belongs to the group of medicines called H2 receptor antagonists. It is used in the management of intestinal, benign and post-operative ulcers. Peptic or intestinal ulcers are open sores that develop on the inside lining of your stomach and the upper part of your small intestine, causing stomach pain.
MONOLOC 25MG INJECTION is also used to manage reflux oesophagitis (inflammation of lower food pipe due to backflow of acidic stomach contents) and Zollinger-Ellison Syndrome (small tumour in the first part of your intestine due to excessive gastrin secretion).
Avoid smoking during the management with MONOLOC 25MG INJECTION, as it may delay healing or worsen the ulcers. Before receiving MONOLOC 25MG INJECTION, inform your doctor if you have stomach cancer, kidney, lung, heart or immunity problems, porphyria (rare blood disorder) or diabetes.
MONOLOC 25MG INJECTION is not recommended for use in pregnant or breastfeeding women unless your doctor finds it essential. MONOLOC 25MG INJECTION is only given to children when they are unable to take the medicine by mouth. Your doctor will determine a proper dose depending on your child’s age, body weight and disease condition. Contact your doctor if you experience any side effects or if any of the symptoms worsen.
Uses Of MONOLOC 25MG INJECTION
Manage:
- and manages intestinal, benign and post-operative ulcers
- reflux oesophagitis
- Zollinger-Ellison Syndrome
How MONOLOC 25MG INJECTION Works
MONOLOC 25MG INJECTION contains ranitidine that effectively manages and heals stomach ulcers by reducing the secretion of stomach acid via inhibition of histamine (H2) receptors present in the stomach walls.
How to use MONOLOC 25MG INJECTION
MONOLOC 25MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide a proper dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of MONOLOC 25MG INJECTION
Uncommon
- stomach pain
- constipation
- nausea
Rare
- skin rashes
- increase in serum creatinine levels (kidney function test)
- changes in the liver function
Stop receiving MONOLOC 25MG INJECTION and contact your doctor immediately if you experience any of the following side effects:
- allergic reactions (rash, itching, hives, swelling of the face, lips, tongue or other body parts, chest pain, wheezing or breathing difficulties, feeling faint especially when standing up, unexplained fever)
- kidney problems (changes in the amount and colour of urine you pass leading to back pain, fever, pain when urinating, blood in urine and changes in the blood test)
- pancreatitis (severe stomach pain)
- irregular or slow heartbeat
How To Manage Side Effects
Nausea:
Take regular sips of a cold drink. Have ginger or peppermint tea. Stick to simple meals. Avoid eating oily or spicy foods. If symptom persists, contact your doctor.
Constipation:
Have enough fiber rich foods like fresh fruits, vegetables, cereals and drink ample amount of water. Exercise more regularly. If symptom persists, contact your doctor.
Stomach pain:
Try to rest and relax. Try to eat smaller meals in small breaks or eat and drink slowly. Keep a heat pad on your stomach. If symptom persists, contact your doctor.
Skin rash:
Avoid hot showers as it can further irritate your skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. If symptom persists, contact your doctor.
Warning & Precautions
Pregnancy
MONOLOC 25MG INJECTION is not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before receiving it.
Breastfeeding
MONOLOC 25MG INJECTION is not recommended for use in breastfeeding women unless considered clearly necessary. Consult your doctor before receiving it.
Driving and Using Machines
MONOLOC 25MG INJECTION has no or negligible effect on driving or using any heavy machineries.
Kidney
MONOLOC 25MG INJECTION should be used with caution in patients with kidney problems. Consult your doctor before receiving it.
Allergy
Do not receive MONOLOC 25MG INJECTION if you are allergic to Ranitidine or any of the other ingredients of this medicine.
Lungs
MONOLOC 25MG INJECTION should be used with caution in patients with lung disease. Consult your doctor before receiving it.
Heart Disease
MONOLOC 25MG INJECTION should be used with caution in patients with heart problems or a history of heart trouble. Consult your doctor before receiving it.
Others
Before receiving MONOLOC 25MG INJECTION, inform your doctor if you:
- have a history of stomach ulcers
- have stomach cancer
- have acute porphyria (a rare genetic condition)
- have diabetes (high blood sugar)
- have problems with your immune system
- experience unexpected weight loss associated with acid indigestion
Use in paediatrics:
Your doctor will prescribe the right dose of MONOLOC 25MG INJECTION depending on age, body weight and health condition of your child. Consult your child’s doctor for advice.
Use in geriatrics:
MONOLOC 25MG INJECTION should be used with caution in elderly patients (aged above 65 years). Consult your doctor before receiving it.
Interactions
A. Drug - Drug interactions:
Before receiving MONOLOC 25MG INJECTION, inform your doctor if you are taking any of the following medicines:
- medicines used to reduce pain and inflammation (Ex. aspirin, ibuprofen, naproxen)
- lidocaine (used to make you feel insensitive to pain)
- medicines used to manage heart problems (Ex. propranolol, procainamide, n-acetylprocainamide)
- diazepam (used for worrying or anxiety problems)
- phenytoin (used to manage fits)
- theophylline (used to manage breathing problems)
- warfarin (used to manage blood clots)
- glipizide (used for diabetes management)
- medicines used to manage HIV infection (Ex. atazanavir, delavirdine)
- gefitinib, erlotinib (used in cancer management)
- medicines used to manage fungal and yeast infections (Ex. itraconazole, ketoconazole)
- sucralfate (used to manage intestinal ulcers)
- medicines used to produce sleepiness and drowsiness during surgeries or to manage insomnia (Ex. midazolam, triazolam)
Overdosage:
MONOLOC 25MG INJECTION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any weird symptoms.
Synopsis
| Drug | : | Ranitidine |
| Pharmacological Category | : | H2 receptor antagonist |
| Therapeutic Indication | : | Peptic ulcer, reflux oesophagitis, Zollinger-Ellison Syndrome |
| Dosage Forms | : | Tablet, Capsule, Injection, Liquid, Oral solution, Syrup |
More Information
- Keep MONOLOC 25MG INJECTION out of reach of children
- Store MONOLOC 25MG INJECTION below 30°C
FAQs About MONOLOC 25MG INJECTION
What if I forget to receive a dose of MONOLOC 25MG INJECTION?
Please stick to the prescribed schedule as agreed with your doctor for optimal efficacy of MONOLOC 25MG INJECTION management. Notify your doctor whenever you forget to receive any dose.
Can MONOLOC 25MG INJECTION cause erectile dysfunction?
Certain acid reflux medicines (H2 blockers) can also affect histamine and cause erectile dysfunction. Whereas some medicines of this class have the highest risk for ED, MONOLOC 25MG INJECTION have a lower risk. Consult your doctor for further queries.
Can MONOLOC 25MG INJECTION cause stomach pain?
MONOLOC 25MG INJECTION may sometimes cause stomach pain. In such case, try to rest and relax. Try to eat smaller meals in small breaks or eat and drink slowly. Keep a heat pad on your stomach. If stomach pain persists, contact your doctor.
Is MONOLOC 25MG INJECTION good for acid reflux?
Yes. MONOLOC 25MG INJECTION heals and stops problems caused by acid in the food pipe or too much acid in the stomach and thus relieves acid reflux or heartburn. Consult your doctor for further queries.
Can I take other medicines with MONOLOC 25MG INJECTION?
Before receiving MONOLOC 25MG INJECTION, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, over the counter or any herbal medicine, as these might cause serious side effects by interacting with each other.
References
1. KD Tripathi. Gastrointestinal Drugs. Essentials of Medical Pharmacology. Eighth Edition, 2019. Page – 698.
2. Morgan KA, Ahlawat R. Ranitidine. NIH: National Library of Medicine, National center of biotechnology Information. StatPearls [Internet]. December 2021. [Accessed on 28th October 2022]. https://www.ncbi.nlm.nih.gov/books/NBK532989/
3. Mark D. Tasch, Olivier Langeron. Aspiration Prevention and Prophylaxis: Preoperative Considerations. Benumof and Hagberg’s Airway Management. Third edition. 2013. Pages 265-279. https://www.sciencedirect.com/topics/neuroscience/ranitidine
4. C van Rensburg, A N Barkun, I Racz, R Fedorak, P C Bornman, C Beglinger, J Balanzó, J Devière, L Kupcinskas, R Luehmann, H Doerfler, S Schäfer-Preuss. Clinical trial: intravenous pantoprazole vs. ranitidine for the prevention of peptic ulcer rebleeding: a multicentre, multinational, randomized trial. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. March 2009. [Accessed 28th October 2022]. https://pubmed.ncbi.nlm.nih.gov/19053987/
5. Delpharm Tours. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed 28th October 2022]. https://www.medicines.org.uk/emc/files/pil.6559.pdf
6. GlaxoSmithKline Bangladesh Limited. Zantac (Ranitidine hydrochloride). [Revised in February 2013] [Accessed on 28th October 2022]. https://gskpro.com/content/dam/global/hcpportal/en_BD/PI/Zantac_Tablet_1_03_2019.pdf
7. Torrent Pharmaceutical Ltd. Ranitin Inj (Ranitidine). [Revised in February 2022] [Accessed on 28th October 2022]. https://www.torrentian.com/pisheet/Upload/PI_Sheet/45.pdf
Useful Diagnostic Tests
- Urea breath test
- Upper GI endoscopy
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