MESACOL 400mg Tablet 10's

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Mesalamine 400mg
By Sun Pharmaceutical Industries Ltd
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Drug Information for MESACOL 400mg Tablet 10's

What is MESACOL 400mg Tablet used for?

MESACOL 400mg Tablet is used for the treatment of ulcerative colitis. It is also recommended to treat mild to moderate Crohn’s disease.

MESACOL 400mg Tablet may also be prescribed for other conditions as determined by the doctor.

How does MESACOL 400mg Tablet work?

MESACOL 400mg Tablet belongs to the class of drugs called anti-inflammatory agents. This drug acts by increasing the mucosal production and diminishing the inflammation by inhibiting the synthesis of prostaglandins and blocking the action of cyclooxygenase enzymes. Inhibition of prostaglandins reduces the inflammation in the colon and other symptoms associated with ulcerative colitis.

How to use MESACOL 400mg Tablet?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Use MESACOL 400mg Tablet as prescribed by your doctor.

  • Mix the required amount of MESACOL 400mg Tablet powder in a glass of cold water and drink it immediately.
  • Swallow the whole tablet. Do not crush or chew the tablet. Take the drug with or without food. However, taking the drug with food prevents stomach upset.
  • Use MESACOL 400mg Tablet enema as suggested by the doctor.

If you miss a dose of MESACOL 400mg Tablet, please use it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for the missed dose.

The overdose symptoms of MESACOL 400mg Tablet may include:

  • Ringing in the ears
  • Confusion
  • Rapid breath
  • Seizures

What are the drugs that interact with MESACOL 400mg Tablet?

Drugs that interact with MESACOL 400mg Tablet include the following:

  • Cidofovir
  • Diatrizoate
  • Iodipamide
  • Iopamidol
  • Lopinavir
  • Tacrolimus

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of MESACOL 400mg Tablet?

The following are the most common side effects of MESACOL 400mg Tablet:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Itching
  • Dyspepsia

The following are the severe side effects, and you may require immediate medical attention:

  • Hair loss
  • Pancreatitis
  • Tremor
  • Gout
  • Shortness of breath
  • Chest pain

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while using MESACOL 400mg Tablet?

  • Avoid using the medicine if you are allergic to MESACOL 400mg Tablet or similar drugs.
  • Avoid consumption of alcohol as it may alter the absorption of MESACOL 400mg Tablet.
  • Monitor your uric acid levels on a regular basis while using MESACOL 400mg Tablet.
  • Avoid MESACOL 400mg Tablet during pregnancy or breastfeeding because the safe use of the drug is not yet established.
  • Do not stop using the medication abruptly unless instructed by the doctor.
  • Do not exceed the dose more than prescribed.

What should you tell your doctor before using MESACOL 400mg Tablet?

  • Tell your doctor if you have any history of heart, liver, kidney or respiratory diseases.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Inform the doctor if you are pregnant or breastfeeding.

Frequently Asked questions about MESACOL 400mg Tablet

  1. Does MESACOL 400mg Tablet enema affect male fertility?
  2. Yes. MESACOL 400mg Tablet enema may alter the sperm count and affects the male fertility. Consult your doctor for further information.

  3. Can I use mesalamine tablet and enema at the same time?
  4. Yes. You can use MESACOL 400mg Tablet tablet and enema at the same time, only when recommended by the doctor.

  5. Is it safe to use MESACOL 400mg Tablet in anaemic patients?
  6. No. It is not safe to use MESACOL 400mg Tablet in patients with anaemia.

  7. Do I need to be monitored for any laboratory parameters while using MESACOL 400mg Tablet?
  8. Blood tests and Kidney function tests must be regularly monitored while using MESACOL 400mg Tablet.

  9. What are the other formulations of MESACOL 400mg Tablet available?
  10. MESACOL 400mg Tablet is available as granules, foam enemas, rectal suppositories, and capsules.



The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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