Lyxumia 10mcg Pen Injection 3ml
Netmeds First Membership
INTRODUCTION ABOUT LYXUMIA 10MCG PEN INJECTION
LYXUMIA 10MCG PEN INJECTION contains Lixisenatide which belongs to the group of medicines called Antidiabetic agents. It is indicated for use as an adjunct to diet and exercise to improve glycemic control in adult patients with type 2 diabetes mellitus in combination with metformin, sulfonylurea (alone or with metformin), pioglitazone (alone or with metformin), and a basal insulin (alone or with metformin).
Diabetes mellitus is a chronic, metabolic disease characterized by elevated levels of blood glucose (or blood sugar), which leads over time to serious damage to the heart, blood vessels, eyes, kidneys, and nerves. Lixisenatide belongs to a class of medicines called glucagon-like peptide-1 (GLP-1) receptor agonists. It helps your body release more insulin when your blood sugar level is high. This helps to improve control of your blood sugar levels
LYXUMIA 10MCG PEN INJECTION is not recommended for patients with type 1 diabetes and diabetic ketoacidosis (a serious complication of diabetes). Before taking inform your doctor if you have pancreatitis, gallstones, hypertriglyceridemia, gastroparesis or inflammatory bowel disease (Crohn disease or ulcerative colitis). It is not recommended for pregnant and breastfeeding women. Consult your doctor for advice.
The common side effects of taking this medicine are hypoglycaemia, headache, nausea, vomiting, diarrhoea. Consult your doctor if any of the above side persists for a longer duration.
USES OF LYXUMIA 10MCG PEN INJECTION
It is used:
- along with diet and exercise to improve control of blood sugar levels in adults with type 2 diabetes
- in combination with (metformin, pioglitazone and basal insulin) when these medicines no longer provide enough control of blood sugar levels on their own
HOW LYXUMIA 10MCG PEN INJECTION WORKS
LYXUMIA 10MCG PEN INJECTION is a selective GLP-1 receptor agonist. It increases glucose-dependent insulin release, decreases glucagon secretion, and slows gastric emptying, thereby reducing the rate at which meal-derived glucose appears in the circulation.
DIRECTIONS FOR USE
Always use LYXUMIA 10MCG PEN INJECTION as advised by your doctor or nurse. Do not inject LYXUMIA 10MCG PEN INJECTION into a vein or muscle. It should only be injected under the skin. Your doctor will prescribe the correct dose and duration depending upon your age, body weight and disease condition.
SIDE EFFECTS OF LYXUMIA 10MCG PEN INJECTION
COMMON
- nausea, vomiting
- diarrhea
- bloating, gas
- constipation
- decreased appetite
- dry mouth
- abdominal pain
- upset stomach, heartburn
- dry mouth
- excessive sweating
- bruising, itching, redness or pain of the injection area
- weakness, tiredness
- headache, dizziness
- motion sickness
- tremor
- nervousness
- cough
Stop using LYXUMIA 10MCG PEN INJECTION and consult your doctor immediately if you experience,
- change in mood, change in vision, confusion, dizziness, fast heartbeat, feeling faint, headache, hunger, shaking, sweating, weakness (Hypoglycemia)
- prolonged severe abdominal pain which may be accompanied by vomiting, pain may spread out towards the back (inflammation of the pancreas)
- difficulty breathing or swallowing, itching, hives, fainting, sudden swelling of the face, lips, tongue or throat, rash, very fast heartbeat (severe allergic reactions including anaphylaxis and angioedema)
- light-headedness and fainting particularly upon standing (Dehydration from prolonged nausea, vomiting or diarrhea, or from not taking enough liquids by mouth)
- any change in the amount, frequency or colour (pale or dark) of urine (kidney problems including kidney failure)
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink lot of fluids, such as water to keep yourself hydrated. Do not take any medicine on your own to manage diarrhoea. Consult your doctor if the symptom has not improved.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Consult your doctor if your headache worsens.
Hypoglycemia
Have foods rich in sugars such as fruit juices, glucose drinks, candies, honey or biscuits. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or a drink and check the blood sugar again. Consult your doctor if there is no improvement in your condition.
Nausea And Vomiting
Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your vomiting worsens.
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedLYXUMIA 10MCG PEN INJECTION is not recommended for use in pregnant women. Consult your doctor before taking this medicine.
BREASTFEEDING
ContraindicatedLYXUMIA 10MCG PEN INJECTION is not recommended for use in breastfeeding women. Consult your doctor before taking this medicine.
DRIVING AND USING MACHINES
Use with CautionDo not drive or operate any machines if you experience any signs of hypoglycemia.
ALCOHOL
Use with CautionAvoid consumption of alcohol while taking LYXUMIA 10MCG PEN INJECTION.
KIDNEY
Use with CautionLYXUMIA 10MCG PEN INJECTION should be used with caution in patients with severe kidney problems or end-stage renal disease (ESRD) or if you are on dialysis.
LIVER
Consult your doctorNo dosage adjustment is necessary for patients with hepatic impairment. Consult your doctor before taking the medicine.
ALLERGY
ContraindicatedDo not take LYXUMIA 10MCG PEN INJECTION if you are allergic or hypersensitive to Lixisenatide or any other ingredients of this medicine.
USE IN PEDIATRICS
ContraindicatedLYXUMIA 10MCG PEN INJECTION is not recommended for children and adolescents below 18 years of age. Consult your doctor for advice.
USE IN GERIATRICS
Use with CautionLYXUMIA 10MCG PEN INJECTION should be used with caution if you are a elderly patient above 65 years of age or older. Consult your doctor for advice.
OTHERS
LYXUMIA 10MCG PEN INJECTION is not recommended in patients with:
- type 1 diabetes
- diabetic ketoacidosis (a serious complication of diabetes)
Before LYXUMIA 10MCG PEN INJECTION inform your doctor if you have:
- inflammation of the pancreas known as pancreatitis
- stones in gallbladder (gallstones)
- high levels of fat in the blood (hypertriglyceridemia)
- severe gastrointestinal disease including a condition called gastroparesis
- or had an inflammatory bowel disease like Crohn disease or ulcerative colitis
- or had or will have surgery on stomach or intestines
- or had a type of thyroid cancer called medullary thyroid carcinoma
- or have had an inherited disorder of your endocrine glands called multiple endocrine neoplasia syndrome type 2
INTERACTIONS
Before taking LYXUMIA 10MCG PEN INJECTION, inform your doctor if you are taking any prescription, non-prescription and herbal supplements or the following:
- medicines used to control blood sugar levels (glyburide, gliclazide and glimepiride)
- a basal insulin used to control blood sugar levels such as insulin glargine and NPH insulin
- medicines that increase the heart rate or that affect the heart rhythm
- warfarin (blood thinner)
- birth control pills
- acetaminophen (used to manage pain and fever)
- atorvastatin (used to lower cholesterol)
- antibiotics (used to manage infection)
Overdosage:
If you or anyone else accidentally uses more of LYXUMIA 10MCG PEN INJECTION consult your doctor immediately or visit nearby hospital.
SYNOPSIS
| Drug | : | Lixisenatide |
| Pharmacological Category | : | Selective GLP-1 receptor agonist |
| Therapeutic Indication | : | Type 2 diabetes mellitus along with diet and exercise |
| Dosage Forms | : | Injection |
MORE INFORMATION
- Keep LYXUMIA 10MCG PEN INJECTION out of reach of children
- Store LYXUMIA 10MCG PEN INJECTION at temperature 2-8°C
FAQs ABOUT LYXUMIA 10MCG PEN INJECTION
Q: What is LYXUMIA 10MCG PEN INJECTION used for?
A: It is indicated for use as an adjunct to diet and exercise to improve glycemic control in adult patients with type 2 diabetes mellitus in combination with metformin, sulfonylurea (alone or with metformin), pioglitazone (alone or with metformin), and a basal insulin (alone or with metformin).
Q: How and when to use LYXUMIA 10MCG PEN INJECTION?
A: Always use LYXUMIA 10MCG PEN INJECTION as advised by your doctor or nurse. Do not inject LYXUMIA 10MCG PEN INJECTION into a vein or muscle. It should only be injected under the skin. Your doctor will prescribe the correct dose and duration depending upon your age, body weight and disease condition.
Q: What to do if I forgot a dose of LYXUMIA 10MCG PEN INJECTION?
A: If you miss a dose of LYXUMIA 10MCG PEN INJECTION, use it within the hour before your next meal. Never take two doses on the same day to make up for a missed dose. Do not stop using LYXUMIA 10MCG PEN INJECTION without talking to your doctor.
Q: Will taking a higher dose of LYXUMIA 10MCG PEN INJECTION be more effective?
A: No, taking a higher dose of LYXUMIA 10MCG PEN INJECTION will not be effective. Always stick to the dose and duration prescribed by your doctor.
Q: What precautions do I need to follow while using LYXUMIA 10MCG PEN INJECTION?
A: LYXUMIA 10MCG PEN INJECTION is not recommended for patients with type 1 diabetes and diabetic ketoacidosis (a serious complication of diabetes). Before using inform your doctor if you have pancreatitis, gallstones, hypertriglyceridemia, gastroparesis or inflammatory bowel disease (Crohn disease or ulcerative colitis).
REFERENCES
1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 270.
2. J Pharm Technol. Lixisenatide: A New Option for Managing Type 2 Diabetes. National Library of Medicine. June 07, 2017. [Accessed on January 19th, 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998422/
3. Sanofi-Aventis Canada Inc. May 23, 2017. [Accessed on January 19th, 2024] https://pdf.hres.ca/dpd_pm/00039567.PDF
4. Lixisenatide (Lyxumia®). October 30th, 2020. [Accessed on January 19th, 2024] https://medicines.bedfordshirelutonandmiltonkeynes.icb.nhs.uk/wp-content/uploads/2021/01/Lixisenatide-Prescribing-fact-sheet-Updated-November-2020-final.pdf
5. Sanofi. [Accessed on January 19th, 2024] https://www.campus.sanofi/dam/jcr:53fd29ba-1ff1-4722-b0d1-f3bab11bb70b/lyxumia-pi-gb-nov-2022.pdf
6. CDSCO. Lixisenatide. [Accessed on January 19th, 2024] https://cdscoonline.gov.in/CDSCO/Drugs
USEFUL DIAGNOSTIC TESTS
- HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
- Blood Glucose Fasting (FBS)
- Post Prandial Blood Sugar (PPBS)
- Insulin - Fasting
- Netmeds Diabetic Checkup
- Advance Diabetes Monitoring (Senior Female)
- Jaanch Diabetic Profile Basic
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