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Drug Information

What is Lercanidipine used for?

Lercanidipine is used in the treatment of hypertension.

Lercanidipine may also be prescribed for other conditions as determined by the doctor.

How does Lercanidipine work?

Lercanidipine belongs to the class of drugs called calcium channel blockers. It works by inhibiting the influx of extracellular calcium across the myocardial and vascular smooth muscle cell membranes. This helps in the dilation of coronary and systemic arteries and reduces the blood pressure.

How to take Lercanidipine?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Lercanidipine as prescribed by your doctor.

Swallow the tablet whole. Do not crush or chew the tablet. Take the drug with or without food. However, taking the drug with food prevents stomach upset.

If you miss a dose of Lercanidipine, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

What are the drugs that interact with Lercanidipine?

Drugs that interact with Lercanidipine include the following:

  • Amiodarone
  • Carbamazepine
  • Cimetidine
  • Digoxin
  • Hydralazine
  • Levodopa
  • Metoprolol
  • Midazolam
  • Minoxidil
  • Moxisylyte
  • Moxonidine
  • Nicorandil
  • Phenytoin
  • Quinidine
  • Rifampicin
  • Terfenadine

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Lercanidipine?

The following are the most common side effects of Lercanidipine:

  • Headache
  • Sleeplessness
  • Nausea
  • Vomiting
  • Muscle pain
  • Swollen ankles or wrists
The following are the severe side effects and you may require immediate medical attention:

  • Dizziness
  • Fast heartbeat
  • Mild swelling of the gum
  • Increased urinary frequency

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Lercanidipine?

  • Avoid using the medicine if you are allergic to Lercanidipine or similar drugs.
  • Seek doctor’s advice before taking any other drug or herbal products while on Lercanidipine.
  • Avoid consumption of alcohol as it may worsen the side effects of Lercanidipine.
  • Do not exceed the dose more than what is prescribed.
  • Do not stop using the medication abruptly unless instructed by the doctor. Stopping the medication suddenly may cause the illness to return.
  • Avoid Lercanidipine during pregnancy or breastfeeding because the safe use of the drug is not yet established.
  • Be cautious while taking Lercanidipine if you have any liver or kidney impairment.

You are advised not to take Lercanidipine if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discoloration.

What should you tell your doctor before taking  Lercanidipine?

  • Tell your doctor if you have had a pacemaker implant.
  • Inform the doctor if you have liver or kidney problems.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.

Frequently asked questions about Lercanidipine


  1. Does Lercanidipine interfere with laboratory tests?
  2. Use of Lercanidipine may cause alteration in the results of liver function tests. You must consult your doctor before undergoing any tests.

  3. How should Lercanidipine be stored?
  4. Store the drug at room temperature and avoid exposure to sunlight and moisture.

  5. Do I need to be monitored for any laboratory parameters while taking Lercanidipine?
  6. Yes. Blood pressure of the patient should be monitored while taking Lercanidipine.

  7. Should I follow any dietary recommendations while using Lercanidipine?
  8. You must avoid taking grapefruit or grapefruit juice while using Lercanidipine. Consult your doctor for further information.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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