LOBULA 0.5 Tablet 10's

Introduction About LOBULA 0.5 TABLET

LOBULA 0.5 TABLET contains Lobeglitazone which belongs to the group of medicines called Antidiabetic agents. It is used to manage type 2 diabetes mellitus patients who are inadequately controlled by diet and exercise and for whom where other anti-diabetic is inappropriate. Diabetes mellitus is a chronic, metabolic disease characterized by elevated levels of blood glucose (or blood sugar), which leads over time to serious damage to the heart, blood vessels, eyes, kidneys, and nerves.

Lobeglitazone acts as an insulin sensitizer by binding and activating peroxisome proliferator-activated receptors (PPAR) gamma within fat cells. Also, by promoting the binding of insulin at fat cells, LOBULA 0.5 TABLET has been shown to reduce blood sugar levels, lower hemoglobin A1C (HbA1C) levels, and improve lipid and liver profiles.

LOBULA 0.5 TABLET is not recommended for patients with liver impairment. Dosage adjustment is not necessary for renal impairment patients. The common side effects of taking this medicine are edema and weight gain. Consult your doctor if any of the above side persists for a longer duration.

Uses Of LOBULA 0.5 TABLET

• Used to manage type 2 diabetes mellitus patients

How LOBULA 0.5 TABLET Works

LOBULA 0.5 TABLET acts as an insulin sensitizer by binding and activating peroxisome proliferator-activated receptors (PPAR) gamma within fat cells. Also, by promoting the binding of insulin at fat cells, LOBULA 0.5 TABLET has been shown to reduce blood sugar levels, lower hemoglobin A1C (HbA1C) levels, and improve lipid and liver profiles.

How to use LOBULA 0.5 TABLET

Take LOBULA 0.5 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration depending upon your age, body weight and disease condition.

Side Effects Of LOBULA 0.5 TABLET

Warning & Precautions

Pregnancy

Consult your doctor

There is limited information available regarding pregnant women. Hence, consult your doctor before taking LOBULA 0.5 TABLET.

Breastfeeding

Consult your doctor

There is limited information available regarding breastfeeding women. Hence, consult your doctor before taking LOBULA 0.5 TABLET.

Kidney

Use with Caution

LOBULA 0.5 TABLET should be used with caution in patients with kidney impairment. Dosage adjustment is not necessary for patients with mild to moderate renal impairment. Consult your doctor before taking the medicine.

Liver

Contraindicated

LOBULA 0.5 TABLET is not recommended for use in patients with acute liver diseases or increased serum transaminase levels. Consult your doctor before taking the medicine.

Allergy

Contraindicated

Do not take LOBULA 0.5 TABLET if you are allergic or hypersensitive to Lobeglitazone or any other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Before taking LOBULA 0.5 TABLET, inform your doctor if you are taking any prescription, non-prescription and herbal supplements.

Overdosage:

If you or anyone else accidentally took more LOBULA 0.5 TABLET consult your doctor immediately or nearby hospital.

Synopsis

More Information

• Keep LOBULA 0.5 TABLET out of reach of children
• Store LOBULA 0.5 TABLET at room temperature

FAQs About LOBULA 0.5 TABLET

Q: What is LOBULA 0.5 TABLET used for?

A: It is used to manage type 2 diabetes mellitus patients who are inadequately controlled by diet and exercise and for whom where other anti-diabetic is inappropriate.

Q: How and when to take LOBULA 0.5 TABLET?

A: Take LOBULA 0.5 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration depending upon your age, body weight and disease condition.

Q: What to do if I forgot to take a dose of LOBULA 0.5 TABLET?

A: If you forgot to take a dose of LOBULA 0.5 TABLET, take it as soon as you remember. However, if it is time for the next dose of LOBULA 0.5 TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of LOBULA 0.5 TABLET to compensate the missed ones.

Q: Can I stop taking LOBULA 0.5 TABLET without consulting the doctor?

A: No. You should not stop taking LOBULA 0.5 TABLET without consulting the doctor because it may cause some side effects.

Q: Will taking a higher dose of LOBULA 0.5 TABLET be more effective?

A: No, taking a higher dose of LOBULA 0.5 TABLET will not be effective. Always stick to the dose and duration prescribed by your doctor.

Q: What precautions do I need to follow while taking LOBULA 0.5 TABLET?

A: LOBULA 0.5 TABLET is not recommended for patients with liver impairment. Dosage adjustment is not necessary for renal impairment patients.

Q: How much LOBULA 0.5 TABLET should I take?

A: LOBULA 0.5 TABLET should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.

References

1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 270.

2. Joonsang Yoo, Jimin Jeon, Minyoul Baik, and Jinkwon Kim. Lobeglitazone, a novel thiazolidinedione, for secondary prevention in patients with ischemic stroke: a nationwide nested case-control study. National Library of Sceience. May 05, 2023 [Accessed on December 28th, 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163714/

3. Pubchem. [Accessed on December 28th, 2023] https://pubchem.ncbi.nlm.nih.gov/compound/Lobeglitazone

4. Drugbank.com. [Accessed on December 28th, 2023] https://go.drugbank.com/drugs/DB09198

5. WHO. Diabetes. [Accessed on December 28th, 2023] https://www.who.int/health-topics/diabetes#tab=tab_1

6. Larenon.com. [Accessed on December 28th, 2023] https://www.larenon.com/wp-content/uploads/2023/03/LOBULA-0.5-LBL.pdf

7. Jaehyun Bae, Taegyun Park, Hyeyoung Kim, Minyoung Lee, and Bong-Soo. Lobeglitazone: A Novel Thiazolidinedione for the Management of Type 2 Diabetes Mellitus. April 19, 2021 [Accessed on December 28th, 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164939/

Useful Diagnostic Tests

• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Blood Glucose Fasting (FBS)
• Post Prandial Blood Sugar (PPBS)
• Insulin - Fasting
• Netmeds Diabetic Checkup
• Advance Diabetes Monitoring (Senior Female)
• Jaanch Diabetic Profile Basic

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)

Last updated on 30 Dec 2023 | 06:10 PM(IST)